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Rat Cytokine ELISA Kits

 
Product   Principle   Data   Literature   Price/Order   Message
 
 
 
 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers

 

Rat TNFa ELISA EA-3001


Tumour Necrosis Factor alpha (TNFa), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. The protein is also important for angiogenesis that is critical to the growth, progression, and metastasis of solid tumors. Furthermore, TNFa is associated with obesity. It is chronically elevated in adipose tissues of obese rodents and humans and may represent an important link between obesity and insulin resistance. In both obese mice and humans, TNFa is overexpressed in adipose tissue. TNFa inhibits insulin signaling, at least in part by blocking insulin receptor tyrosine kinase activity and inducing serine phosphorylation of insulin receptor substrate-1 (IRS-1). However, it is unclear what the physiological stimulator of TNFa production by adipocyte during obesity is and how IRS-1 inhibits the tyrosine kinase activity of the insulin receptor after TNFa treatment of the cells. A better understanding of the connection(s) between the TNFa and the insulin signaling pathways could be important to find a cure for the state of insulin resistance observed during obesity.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat FGFb ELISA Kit EA-3009


Fibroblast growth factor (FGF)-2, also known as basic FGF (FGFb), is a powerful stimulator of angiogenesis in vivo. It also plays an important role during prenatal developmental processes and postnatal growth, by promoting cellular proliferation and differentiation in vitro. 

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat IFNy ELISA EA-3003


Interferons (IFNs) are potent extracellular protein mediators of host defence and homoeostasis. They are cytokines produced by the cells of the immune system in response to challenges by foreign agents such as viruses, parasites and tumor cells. It is produced by a wide variety of cells in response to the presence of double-stranded RNA, a key indicator of viral infection. IFNs are divided into two major subgroups. Type I IFNs all bind to a type I IFN receptor, such as IFN-a and IFN-ß. IFN-y is the sole type II IFN, which binds to a distinct type II receptor. Almost all cell types produce type I IFNs, while the type II IFN-y is produced in T cells and natural killer (NK) cells upon immunological stimulation. IFN-y coordinates a diverse array of cellular programs through transcriptional regulation of immunologically relevant genes. Cellular effects of IFN-y includes up-regulation of pathogen recognition, antigen processing and presentation, the antiviral state, inhibition of cellular proliferation and effects on apoptosis, activation of microbicidal effector functions, immunomodulation, and leukocyte trafficking.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat IL-1a ELISA EA-3004


IL-1a and IL-1ß are prominent agonists mediating inflammatory and immunomodulatory effects. Both are produced by macrophages, monocytes and dendritic cells. They are important part of the inflammatory response against infection. They increase the expression of adhesion factors on endothelial cells to enable transmigration of leukocytes to sites of infection. IL-1a is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. It is produced by many cell types but is only secreted by monocytes and macrophages.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat IL-1b ELISA EA-3005


IL-1a and IL-1ß are prominent agonists mediating inflammatory and immunomodulatory effects. Both are produced by macrophages, monocytes and dendritic cells. They are important part of the inflammatory response against infection. They increase the expression of adhesion factors on endothelial cells to enable transmigration of leukocytes to sites of infection. IL-1ß production in peripheral tissue has also been associated with hyperalgesia (increased sensitivity to pain) associated with fever.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat IL-5 ELISA Kit EA-3010


IL-5 is a protein that produced by T-cells. It regulates the activation of eosinophils, and promotes the production of cytotoxic lymphocytes. It also acts as a differentiation and proliferation factor for B-cells. The elevated generation of this cytokine has been reported to be related to asthma or hypereosinophilic syndromes.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat IL-6 ELISA EA-3002


Interleukin-6 (IL-6) is a multifunctional cytokine that regulates the immune response, hematopoiesis, the acute phase response, and inflammation. Deregulation of IL-6 production is implicated in the pathology of several disease processes. Its levels are observed in several diseases, including rheumatoid arthritis (RA). IL-6 plays roles in both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response. In addition, like TNFa, IL-6 is another adipocyte secretory product that may be involved in insulin resistance. IL-6 is a cytokine secreted by many cells, including adipocytes and adipose stromal cells. IL-6 secretion is increased in the adipocytes of obese subjects and may be important either as a circulating hormone or as a local regulator of insulin action. IL-6 has been implicated in the development of insulin resistance and type 2 diabetes in obese individuals. Like TNF, IL-6 inhibits the expression of LPL, but, unlike TNF, IL-6 does not stimulate lipolysis.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat IL-15 ELISA Kit EA-3011


IL-15 is a pleiotropic cytokine that is important for both innate and adaptive immune cell homeostasis, as well as peripheral immune function. It plays an important role in the development and the survival of the NK cell lineage. It also plays a role in peripheral immune functions such as T lymphocyte trafficking, innate immune IFN- γ production, and host defense against infectious pathogens.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat IP-10 ELISA Kit EA-3012


IFN-gamma-inducible protein (IP-10) is a member of the chemokine family of cytokines and is produced in a variety of cells in response to interferon gamma and lipopolysaccharide. IP-10 plays several roles, such as the chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, the promotion of T cell adhesion to endothelial cells, and the inhibition of bone marrow colony formation.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat Leptin ELISA Kit EA-3013


Leptin plays a key role in regulating energy intake and energy expenditure, including the regulation of appetite and metabolism. Leptin is produced by adipose tissue and the level of circulating leptin is directly proportional to the total amount of fat in the body. Leptin is also found to stimulate endothelial cell proliferation and angiogenesis.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat MCP-1 ELISA EA-3006


Monocyte chemotactic protein-1 (MCP-1), also called CCL2, is an inflammatory chemokine that plays important roles in recruiting monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. MCP-1 also involves in obesity and insulin resistance by the induction of an inflammatory response (macrophage infiltration) in fatty tissue. In addition, MPC-1 has been found in the joints of people with rheumatoid arthritis where may serve to recruit macrophages and perpetuate the inflammation in the joints.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat MIP-1a ELISA EA-3008


Macrophage Inflammatory Protein-1 (MIP-1) is a member of the C-C subfamily of chemokines that exhibit a variety of proinflammatory activities in vitro including leukocyte chemotaxis. MIP-1 is a major factor produced by macrophages after stimulated with bacterial endotoxins. It activates granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation. It also induces the synthesis and release of other pro-inflammatory cytokines such as IL-1, IL-6 and TNFa from fibroblasts and macrophages. In addition to its proinflammatory activities, MIP-1 inhibits the proliferation of hematopoietic stem cells in vitro and in vivo.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat Rantes ELISA EA-3007


RANTES is a chemotactic protein for T cells, eosinophils, and basophils. RANTES is produced by circulating T-cells. The synthesis of RANTES is induced by TNF-alpha and IL1-alpha. It plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines that are released by T cells, Rantes also induces the proliferation and activation of certain natural-killer (NK) cells to form CC-Chemokine-activated killer cells. It is also an HIV-suppressive factor released from CD8+ T cells. RANTES increases the adherence of monocytes to endothelial cells.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat TGFb ELISA EA-3016


The transforming growth factor beta 1 (TGF-ß1) gene codes a multifunctional cytokine that controls proliferation, differentiation, and other functions in many cell types, including cancer cells, the surrounding stromal cells, immune cells, endothelial and smooth-muscle cells. It causes immunosuppression and angiogenesis, which makes the cancer more invasive. TGF-ß also converts effector T-cells, which normally attack cancer with an inflammatory (immune) reaction, into regulatory (suppressor) T-cells, which turn off the inflammatory reaction. TGF-ß induces apoptosis in numerous cell types. TGF-ß can act on adipocyte precursor cells. TGF- ß1 has been shown to be a potent inhibitor of the differentiation of adipogenic cell lines. In addition, a differentiation-defective, insulin-independent cell linederived from the adipogenic cell line 1246 produces in its conditional medium a TGF- ß1-like polypeptide which could modulate the cell ability to differentiate in an autocrine fashion. Increased TGF-b1 expression was associated with BMI and abdominal adipose tissue in morbid obesity.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat SCF ELISA Kit EA-3014


Stem cell factor (SCF) is a growth factor for multiple cell types. It is expressed in glioma cells and produced as a result of a variety of the types of brain injury. SCF expression encourages the growth of blood vessels needed to expand tumors, rather than directly involving in the tumor cell proliferation.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers




Rat VEGF ELISA Kit EA-3015


Vascular endothelial growth factor (VEGF) is one of the most potent tumor-angiogenic factors. VEGF is used by oxygen-hungry cells to promote the growth of blood vessels and stimulate cell proliferation and angiogenesis.

 
 Benefits:
  • Cost-effective analysis - High Quality with the most competitive price.
  • Efficient and flexible - Multiple samples can be analyzed simultaneously.

  • Specific - A pair of highly selective antibodies are specifically against the cytokine. 
  • Simple procedure - All in one system with a pre-coated 96-well plate.

Click Here for Price Information and Catalogue Numbers