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miRNA Arrays

 
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Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.
 

Cancer miRNA Array AP-0003


MiRNAs have been widely known to function as either oncogenes or tumor suppressors under certain conditions. The dysregulated miRNAs have been shown to affect the hallmarks of cancer, including sustaining proliferative signaling, eluding growth suppressors, resisting cell death, and inducing angiogenesis. An increasing number of studies have identified miRNAs as potential biomarkers for human cancer diagnosis, prognosis and therapeutic targets. Signosis has developed Cancer miRNA Array including 132 cancer-related miRNAs for cancer research.

List of Applicable miRNAs

Let-7a-5p Let-7b-5p Let-7c-5p Let-7d-5p Let-7e-5p Let-7f-5p Let-7g-5p Let-7i-5p miR-1 miR- 7
miR-9-5p miR-10a-5p miR-15a-5p miR-15b-5p miR-16-5p miR-17-5p miR-18b-5p miR- 18b miR-19a-3p miR-19b-3p
miR-20a-5p miR-21-5p miR-25-3p miR-28-5p miR-34a-5p miR-99a-5p miR-122a-5p miR-124a-3p miR-125a-5p miR-125b-5p
miR-126-3p miR-131 miR-133a-3p miR-133b miR-143-3p miR-145-5p miR-146a-5p miR-146b-5p miR-148a-3p miR-155-5p
miR-181a-5p miR-181b-5p miR-181c-5p miR-182-5p miR-192-5p miR-194-5p miR-195-5p miR-199a-5p miR-199b-5p miR-199a*-3p
miR-200a-3p miR-200c-3p miR-204-5p miR-206 miR-216-5p miR-223-3p miR-224-5p miR-342-3p mir-376c-3p miR-375
miR-9-1-5p miR-10b-5p miR-17-3p miR-22-3p miR-23a-3p miR-24-3p miR-26a-5p miR-26b-5p miR-27a-3p miR-27b-3p
miR-29a-3p miR-29b-3p miR-29c-3p miR-30a-3p miR-30a-5p miR-30b-5p miR-30c-5p miR-92-3p miR-92b-3p miR-93-5p
miR-95-3p miR-101-1-3p miR-103-3p miR-106a-5p miR-106b-5p miR-107 miR-128a-3p miR-128b-3p miR-132-3p miR-134-5p
miR-135b-5p miR-136-5p miR-137 miR-140-5p miR-141-3p miR-142-3p miR-149-5p miR-150-5p miR-151-3p miR-153-3p
miR-154-5p miR-181d-5p miR-183-5p miR-185-5p miR-186-5p miR-188-5p miR-190-5p miR-191-5p miR-196a-5p miR-196b-5p
miR-197-3p miR-198 miR-200b-3p miR-202-5p miR-203a miR-205-5p miR-210-3p miR-214-3p miR-215-5p miR-218-5p
miR-219 miR-221-3p miR-222-3p miR-296-5p miR-372-3p miR-373-5p miR-488-5p miR-100-5p miR-127 miR-142-5p
miR-31-5p miR-181a-3p  RNU48              
 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Human miRNA Array I AP-0001


Newly discovered microRNAs (miRNAs) are important to the regulation of gene expression, and up to 30% of mammalian genes may be regulated by miRNAs. So far, more than 400 miRNAs have been identified in the human genome and many of them are only different in one or a few nucleotides. The expression of mature miRNAs is tissue-specific and the abundance of miRNAs varies over several orders of magnitude. More importantly, mis-regulation of miRNA expression may contribute to human cancers. Systematic profiling of miRNA expression plays the key role in the research of a number of cancers.


Signosis' Human miRNA array I allows you to profile 60 of the most popular miRNAs and their isoforms.

List of Applicable miRNAs

let-7a-5p let-7b-5p let-7c-5p let-7d-5p let-7e-5p let-7f-5p let-7g-5p let-7i-5p miR-1 miR-7-5p
miR-9-5p miR-10a-5p miR-15a-5p miR-15b-5p miR-16-5p miR-17-5p miR-18a-5p miR-18b-5p miR-19a-3p miR-19b-3p
miR-20a-5p miR-21-5p miR-25-3p miR-28-5p miR-34a-5p miR-99a-5p miR-122a-5p miR-124a-3p miR-125a-5p miR-125b-5p
miR-126-3p miR-131 miR-133a-3p miR-133b miR-143-3p miR-145-5p miR-146a-5p miR-146a-5p miR-148a-3p miR-155-5p
miR-181a-5p miR-181b-5p miR-181c-5p miR-182-5p miR-192-5p miR-194-5p miR-195-5p miR-199a-5p miR-199a-5p miR-199a*-3p
miR-200a-3p miR-200c-3p miR-204-5p miR-206 miR-216-5p miR-223-3p miR-224-5p miR-342-3p mir-376c-3p miR-375
 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Human miRNA Array II AP-0002


Signosis' Human miRNA array II allows you to profile 72 of the most popular miRNAs and their isoforms.

List of Applicable miRNAs

miR-9-1-5p

miR-10b-5p miR-17-3p miR-22-3p miR-23a-3p miR-24-3p miR-26a-5p miR-26b-5p miR-27a-3p miR-27b-3p
miR-29a-3p miR-29b-3p miR-29c-3p miR-30a-3p miR-30a-5p miR-30b-5p miR-30c-5p miR-92-3p miR-92b-3p miR-92-3p
miR-95-3p miR-101-1-3p miR-103-3p miR-106a-5p miR-106b-5p miR-107 miR-128a-3p miR-128b-3p miR-132-3p miR-134-5p
miR-135b-5p miR-136-5p miR-137 miR-140-5p miR-141-3p miR-142-3p miR-149-5p miR-150-5p miR-151-3p miR-153-3p
miR-154-5p miR-181d-5p miR-183-5p miR-185-5p miR-186-5p miR-188-5p miR-190-5p miR-191-5p miR-196a-5p miR-196b-5p
miR-197-3p miR-198 miR-200b-3p miR-202-5p miR-203a miR-205-5p miR-210-3p miR-214-3p miR-215-5p miR-218-5p
miR-219 miR-221-3p miR-222-3p miR-296-5p miR-372-3p miR-373-5p miR-488-5p miR-100-5p miR-127 miR-142-5p
miR-31-5p miR-181a-3p RNU48              
 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Human miRNA Array III AP-0008


Signosis' Human miRNA array III allows you to profile 132 of the most popular miRNAs and their isoforms.

List of Applicable miRNAs

Let-7a-5p Let-7b-5p Let-7c-5p Let-7d-5p Let-7e-5p Let-7f-5p Let-7g-5p Let-7i-5p miR-1 miR-7-5p
miR-9-5p miR-10a-5p miR-15a-5p miR-15b-5p miR-16-5p miR-17-5p miR-18a-5p miR-18b-5p miR-19a-3p miR-19b-3p
miR-20a-5p miR-21-5p miR-28-5p miR-28-5p miR-34a-5p miR-99a-5p miR-122a-5p miR-124a-3p miR-125a-5p miR-125b-5p
miR-126-3p miR-131 miR-133a-3p miR-133b miR-143-3p miR-145-5p miR-146a-5p miR-146b-5p miR-148a-3p miR-155-5p
miR-181a-5p miR-181b-5p miR-181c-5p miR-182-5p miR-192-5p miR-194-5p miR-195-5p miR-199a-5p miR-199b-5p miR-199a*-3p
miR-200a-3p miR-200c-3p miR-204-5p miR-206 miR-216-5p miR-223-3p miR-224-5p miR-342-3p mir-376c-3p miR-375
miR-9-1-5p miR-10b-5p miR-17-3p miR-22-3p miR-23a-3p miR-24-3p miR-26a-5p miR-26b-5p miR-27a-3p miR-27b-3p
miR-29a-3p miR-29b-3p miR-29c-3p miR-30a-3p miR-30a-5p miR-30b-5p miR-30c-5p miR-92-3p miR-92b-3p miR-93-5p
miR-95-3p miR-101-1-3p miR-103-3p miR-106a-5p miR-106b-5p miR-107 miR-128a-3p miR-128b-3p miR-132-3p miR-134-5p
miR-135b-5p miR-136-5p miR-137 miR-140-5p miR-141-3p miR-142-3p miR-149-5p miR-150-5p miR-151-3p miR-153-3p
miR-154-5p miR-181d-5p miR-183-5p miR-185-5p miR-186-5p miR-188-5p miR-190-5p miR-191-5p miR-196a-5p miR-196b-5p
miR-197-3p miR-198 miR-200b-3p miR-202-5p miR-203a miR-205-5p miR-210-3p miR-214-3p miR-215-5p miR-218-5p
miR-219 miR-221-3p miR-222-3p miR-296-5p miR-372-3p miR-373-5p miR-488-5p miR-100-5p miR-127 miR-142-5p
miR-31-5p miR-181a-3p RNU48              

 

 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Human miRNA Array IV AP-0009


Signosis' Human miRNA array IV allows you to profile 100 miRNAs.

List of Applicable miRNAs

miR-138 miR-139 miR-105 miR-130a miR-135a miR-147 miR-152 miR-154-3p miR-184 miR-187
miR-189 miR-211 miR-212 miR-217 miR-22 miR-220 miR-299-3p miR-299-5p miR-301 miR-302a-3p
miR-302a-5p miR-302b-3p miR-302b-5p miR-302c-3p miR-302c-5p miR-302d miR-30d miR-30e-3p miR-30e-5p miR-32
miR-320 miR-323 miR-324-3p miR-324-5p miR-325 miR-326 miR-328 miR-329 miR-33 miR-330
miR-331 miR-335 miR-337 miR-338 miR-339 miR-33b miR-340 miR-345 miR-346 miR-34b
miR-34c miR-361 miR-362 miR-363-3p miR-363-5p miR-365 miR-367 miR-369-3p miR-369-5p miR-370
miR-371 miR-373-5p miR-374 miR-376a-3p miR-376a-5p miR-376b miR-377 miR-378 miR-379 miR-380-3p
miR-380-5p miR-381 miR-382 miR-383 miR-384 miR-409-5p miR-410 miR-411 miR-412 miR-422a
miR-422b miR-423 miR-424 miR-425 miR-425-5p miR-429 miR-432-5p miR-432-3p miR-433 miR-448
miR-449 miR-449b miR-450 miR-451 miR-452-5p miR-452-3p miR-453 miR-455 miR-483 U6
 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Apoptosis miRNA Array AP-0004


Numerous miRNAs have been reported to have an influence on the regulation of apoptotic cell signaling such as the overexpression of miR-145, miR-216, miR-182, and miR-96 miRNA to decrease caspase-3 activation. Signosis has developed a miRNA array for targeting 52 miRNAs that have been shown in literature to be involved in apoptosis.

 

List of Applicable miRNAs

Let-7a-5p Let-7b-5p Let-7c-5p Let-7d-5p Let-7e-5p Let-7f-5p Let-7g-5p Let-7i-5p miR-1 miR-7-5p
miR-10a-5p miR-15a-5p miR-15b-5p miR-16-5p miR-21-5p miR-25-3p miR-28-5p miR-133b miR-145-5p miR-148
miR-155-5p miR-182-5p miR-204-5p miR-216-5p miR-224-5p mir-376c-3p miR-24-3p miR-101 miR-142 miR-150-5p
miR-151-3p miR-153-3p miR-188-5p miR-196a-5p miR-197-3p miR-202-5p miR-210-3p miR-214-3p miR-218-5p miR-296-5p
miR-144 miR-152 miR-184 miR-337 miR-338 miR-345 miR-371 miR-96 miR-369-5p miR-369-3p
miR-193a miR-193b RUN48              
 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Mouse miRNA Array AP-0005


Signosis' mouse miRNA arrays allow you to profile 119 miRNAs from mouse samples.

 

List of Applicable miRNAs

Let-7a-5p Let-7b-5p Let-7c-5p Let-7d-5p Let-7e-5p Let-7f-5p Let-7g-5p Let-7i-5p miR-1 miR-7-5p
miR-9-5p miR-10a-5p miR-15a-5p miR-15b-5p miR-16-5p miR-17-5p miR-18a-5p miR-18b-5p miR-19a-3p miR-19b-3p
miR-20a-5p miR-21-5p miR-25-3p miR-28-5p miR-34a-5p miR-99a-5p miR-122a-5p   miR-125a-5p miR-125b-5p
miR-126-3p   miR-133a-3p miR-133b miR-143-3p miR-145-5p miR-146a-5p miR-146b-5p miR-148a-3p miR-155-5p
miR-181a-5p miR-181b-5p miR-181c-5p miR-182-5p miR-192-5p miR-194-5p miR-195-5p miR-199a-5p    
miR-200a-3p miR-200c-3p miR-204-5p miR-206 miR-216-5p miR-223-3p miR-224-5p miR-342-3p   miR-375
miR-9-1-5p miR-10b-5p   miR-22-3p miR-23a-3p miR-24-3p miR-26a-5p miR-26b-5p miR-27a-3p miR-27b-3p
miR-29a-3p miR-29b-3p miR-29c-3p   miR-30a-5p miR-30b-5p miR-30c-5p miR-92-3p miR-92b-3p miR-93-5p
  miR-101-1-3p miR-103-3p miR-106a-5p miR-106b-5p miR-107 miR-128a-3p miR-128b-3p miR-132-3p miR-134-5p
miR-135b-5p miR-136-5p miR-137 miR-140-5p miR-141-3p   miR-149-5p miR-150-5p miR-151-3p miR-153-3p
miR-154-5p miR-181d-5p miR-183-5p miR-185-5p miR-186-5p miR-188-5p miR-190-5p miR-191-5p miR-196a-5p miR-196b-5p
miR-197-3p   miR-200b-3p miR-202-5p miR-203a miR-205-5p miR-210-3p miR-214-3p miR-215-5p miR-218-5p
miR-219 miR-221-3p miR-222-3p miR-296-5p       miR-100-5p miR-127 miR-142-5p
miR-31-5p miR-181a-3p U6              
 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Rat miRNA Array AP-0006


Signosis' rat miRNA array allows you to profile 113 miRNAs from rat samples.

 

List of Applicable miRNAs

Let-7a-5p Let-7b-5p Let-7c-5p Let-7d-5p Let-7e-5p Let-7f-5p     miR-1 miR-7-5p
miR-9-5p miR-10a-5p   miR-15b-5p miR-16-5p miR-17-5p miR-18a-5p   miR-19a-3p miR-19b-3p
miR-20a-5p miR-21-5p miR-25-3p miR-28-5p miR-34a-5p miR-99a-5p miR-122a-5p miR-124a-3p miR-125a-5p miR-125b-5p
miR-126-3p   miR-133a-3p miR-133b miR-143-3p miR-145-5p miR-146a-5p miR-146b-5p miR-148a-3p  
miR-181a-5p miR-181b-5p miR-181c-5p miR-182-5p miR-192-5p miR-194-5p miR-195-5p miR-199a-5p    
miR-200a-3p miR-200c-3p miR-204-5p miR-206 miR-216-5p miR-223-3p miR-224-5p miR-342-3p   miR-375
miR-9-1-5p miR-10b-5p   miR-22-3p miR-23a-3p miR-24-3p miR-26a-5p miR-26b-5p miR-27a-3p miR-27b-3p
miR-29a-3p miR-29b-3p miR-29c-3p miR-30a-3p miR-30a-5p miR-30b-5p miR-30c-5p miR-92-3p miR-92b-3p miR-93-5p
  miR-101-1-3p miR-103-3p   miR-106b-5p miR-107 miR-128a-3p miR-128b-3p miR-132-3p miR-134-5p
miR-135b-5p miR-136-5p miR-137 miR-140-5p miR-141-3p miR-142-3p   miR-150-5p miR-151-3p miR-153-3p
miR-154-5p miR-181d-5p miR-183-5p miR-185-5p miR-186-5p miR-188-5p miR-190-5p miR-191-5p miR-196a-5p miR-196b-5p
    miR-200b-3p   miR-203a miR-205-5p miR-210-3p miR-214-3p miR-215-5p miR-218-5p
miR-219 miR-221-3p miR-222-3p miR-296-5p       miR-100-5p miR-127 miR-142-5p
miR-31-5p miR-181a-3p U6              
 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.



Stem cell miRNA Array AP-0007


MiRNAs are found to be differentially expressed in stem cells, such as brain-specific miR-124a and miR-9 molecules during neural lineage differentiation. In addition, miRNAs are also reported to regulate cancer stem cells. Signosis has developed a miRNA array specifically to target 69 miRNAs that are shown in literature to be associated with stem cell differentiation and maintenance. The array can be used for human, mouse and rat samples. 
 

 
Benefits:
    • High discriminative power It is able to differentiate all miRNA isoforms. All let7 isoforms can be clearly distinguished in the assay.
    • Linear amplification Captured miRNAs are subjected to T7 amplification without introduction of bias in PCR.
    • No pre-isolation of miRNA - Total RNA can be directly used for the assay without pre-isolation of miRNA.
    • Simple procedure - The assay is simple and straightforward.