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miRNA Luciferase Vector Sets

 
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Benefits:
  • Functional assay It provides functional assays to monitor miRNA expression in cells.
  • Quantitative analysis - Expression and activity of miRNAs are measured through repression of firefly luciferase gene expression.
  • Comprehensive Moniter 7 miRNAs in one assay.
 

Oxidative Stress miRNA Reporter Vector Set


Oxidative stress is caused by an imbalance in the generation and removal of reactive oxygen species (ROS).  ROS elicits a wide spectrum of responses, such as cell proliferation, growth arrest, or apoptosis, which are mainly through gene expression on transcriptional level.  Recent studies have indicated that post-transcriptional control by miRNAs also contributes to the physiological processes. A number of oxidative stress-related miRNAs have been identified.   

Signosis has developed a set of miRNA luciferase reporter vectors to facilitate oxidative stress study. The list of vectors is as follows:

 

List of Applicable Vectors

miR-200a miR-141 miR-125b miR-30b miR-320 miR-144 miR-27b Negative control

 

Sets Available:

Oxidative Stress miRNA Reporter Vector Set (50ng/Vector) LR-4001-50
Oxidative Stress miRNA Reporter Vector Set (2ug/Vector) LR-4001-2000

 

Benefits:
  • Functional assay It provides functional assays to monitor miRNA expression in cells.
  • Quantitative analysis - Expression and activity of miRNAs are measured through repression of firefly luciferase gene expression.
  • Comprehensive Moniter 7 miRNAs in one assay.



Genotoxic Stress Luciferase Reporter Vector Set


Exposure to genotoxic agents such as ultraviolet light, oxidative stress, and chemical mutagens leads to DNA damage, which is a major cause of human cancers. Cellular responses are important to effective defense against genotoxic stress, and recent studies have indicated that miRNAs control the expression of target genes at post-transcriptional level in the process.

Signosis has developed a set of miRNA luciferase reporter vectors to facilitate genotoix stress study. The list of vectors is as follows:

 

List of Applicable Vectors

miR-miR-34a miR-107 miR-21 miR-125b miR-let-7b miR-149 miR-22 Negative control

 

Sets Available:

Genotoxic Stress Luciferase Reporter Vector Set (50ng/Vector) LR-4002-50
Genotoxic Stress Luciferase Reporter Vector Set (2ug/Vector) LR-4002-2000

 

Benefits:
  • Functional assay It provides functional assays to monitor miRNA expression in cells.
  • Quantitative analysis - Expression and activity of miRNAs are measured through repression of firefly luciferase gene expression.
  • Comprehensive Moniter 7 miRNAs in one assay.