Signosis' EL-038 is a stable Ba/F3 cell line expressing EGFR with the D770_N771insSVD insertion in the αC helix loop and the C797S mutation. The cell line was generated by electroporation with a vector containing the mutant EGFR gene, along with GFP and hygromycin resistance. Clones were selected based on hygromycin resistance, GFP expression, and confirmed mutant EGFR protein expression by western blot.
EL-038 EGFR (D770_N771insSVD, C797S) BaF3 Stable Cell Line
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