Erythroid Krüppel-like factor (EKLF) is a zinc-finger transcription factor that plays a crucial role in regulating the differentiation and function of erythroid cells and is essential for the development of the hematopoietic system. The EKLF luciferase reporter vector is designed to study the transcriptional activity of EKLF. The vector contains a EKLF DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report EKLF activity while maintaining a low basal level of transcription.
 
The inclusion of a neomycin resistance gene in the vector allows it to be used for stable cell line selection. In addition, the vector also has a GFP-tag which can be used to monitor transfection efficiency. A map of the vector can be found in the product's image gallery.