Our Services
Personalize your research kit with our customized solutions
Lentivirus Packaging Services
The lentiviral system is a highly efficient method for delivering genetic material into a wide range of biological models. It is particularly effective for transducing non-dividing, quiescent, and hard-to-transfect cells, such as neurons, primary cells, and stem cells.
Lentiviral vectors enable stable, long-term expression by integrating the transgene into the host cell genome. This makes lentiviral delivery an ideal solution for applications requiring durable gene expression, such as functional genomics, cell line engineering, and gene therapy research.
At Signosis, we offer a comprehensive portfolio of lentiviral constructs, libraries, and custom lenti-based solutions. Our products are provided as ready-to-transduce, pre-packaged lentiviral particles with 3rd generation packaging technology, pseudotyped with VSV-G for broad tropism and high transduction efficiency.
We are committed to delivering reliable, high-quality lentiviral solutions to support advanced research and therapeutic development.
Lentivirus production and quality control (QC)
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Purify viral particles using ultracentrifugation and ultrafiltration to remove impurities and increase concentration.
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Measure lentiviral titer by RT-qPCR targeting the LTR region and comparing to a standard curve.
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Perform sterility and mycoplasma testing to ensure purity.
Validate function by transducing cells and detecting fluorescence if applicable.
Target-Based Drug Discovery Services
At Signosis Inc., our Target-Based Drug Discovery services are designed to accelerate the identification and validation of therapeutic candidates with precision and efficiency.
Leveraging our expertise in cell-based assays, reporter systems, and pathway analysis, we support every stage of target-based discovery—from target validation and assay development to compound screening and mechanism-of-action studies.
Our advanced technologies allow for sensitive detection of target engagement, pathway modulation, and functional cellular responses, ensuring reliable and reproducible results.
Whether you are investigating signaling pathways, transcriptional regulation, or disease-relevant biomarkers, our customized solutions are tailored to meet your specific research needs. With a strong emphasis on data quality and biological relevance, Signosis empowers researchers to make informed decisions and advance promising drug candidates with confidence.
Functional assays provide insight into the biological effects of compounds on GPCR signaling. We offer multi-pathway detection services using ELISA or reporter gene methods.
Our screening services are designed to support drug discovery across a range of therapeutic areas, with a strong focus on metabolic diseases. By combining robust assay design with validated cell-based systems, we deliver reliable and reproducible data to accelerate lead identification and characterization.
Custom Stable Cell Line Generation
By choosing this service you will benefit from;
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Quick and Reliable stable cell line generation with minimum turn around time of 8 weeks.
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Experienced Technical Expertise: Our highly experienced scientific team has established 60+ TF luciferase reporter and gene overexpression stable cell lines.
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Exceptional Client Service: The experienced scientists will consult, discuss and conduct your projects effectively. The complete functional test is also available upon your request.
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Mycoplasma Testing: We guarantee the absence of mycoplasma in generated cell lines.
Signosis provides custom services for making stable cell lines with vectors of your choice or vectors available in the Signosis catalog. You can also provide your own cell lines or choose from our in-house collection. The schematic for generating a stable cell line is pictured on the right and the process takes about 5-8 weeks on average, depending on the complexity of the project.
Custom Assay Development
Signosis' products and assays can be customized to suit your project. Probes, plate layout, and more can all be customized to your research specifications. The following products that can be customized include:
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TF Profiling Arrays
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EMSA
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TF Filter Assays
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Cytokine ELISA Plate Arrays
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Cytokine ELISA Strips
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miRNA Arrays
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miRNA Northern Blot Assay Kits
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miRNA Real-Time PCR
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Co-IP Kits
Contact Us
Contact Details
Live Operating Hours
Mon - Fri
8:00 am – 5:00 pm PST
408-747-0771