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Stable Cell Line
Luciferase Reporter Stable Cell Lines
1. Withaferin A induces Nrf2-dependent protection against liver injury: role of Keap1-independent mechanisms. DL Palliyaguru, DV Chartoumpekis, N Wakabayashi. Free Radical Biology and Medicine 2016. http://dx.doi.org/10.1016/j.freeradbiomed.2016.10.003
2. Occurrence and in vitro toxicity of unregulated disinfection by-products in two Saskatchewan drinking water treatment plants. Christena Leigh Watts. Handle Proxy, Universidade Da Coruña, 1 Sept. 2018, hdl.handle.net/10388/11499.
3. Redox-responsive, reversibly-crosslinked thiolated cationic helical polypeptides for efficient siRNA encapsulation and delivery.N Zheng, Z Song, Y Liu, R Zhang, R Zhang, C Yao. Journal of Controlled Release.Volume 205, 10 May 2015, Pages 231–239
4. Targeted delivery of cisplatin to tumor xenografts via the nanoparticle component of nano-diamino-tetrac. Thangirala Sudha, Dhruba J Bharali, Murat Yalcin, Noureldien HE Darwish, Melis Debreli Coskun, Kelly A Keating, Hung-Yun Lin, Paul J Davis, Shaker A Mousa. February 2017 ,Vol. 12, No. 3, Pages 195-205 , DOI 10.2217/nnm-2016-0315.
5. Thymoquinone Modulates Blood Coagulation in Vitro via Its Effects on Inflammatory and Coagulation Pathways. V Muralidharan-Chari, J Kim, A Abuawad, M Naeem. Int. J. Mol. Sci. 2016, 17(4), 474; doi:10.3390/ijms17040474
6. Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 …G Vazquez-Ortiz, C Chisholm, X Xu, TJ Lahusen, C Li… - Breast Cancer Research 2014, Jun 24;16(3):R67. doi: 10.1186/bcr3682.
7. Alcohol promotes migration and invasion of triple-negative breast cancer cells through activation of p38 MAPK and JNK†M Zhao, EW Howard, AB Parris, Z Guo, Q Zhao, X Yang. Molecular Carcinogenesis, 2016, DOI: 10.1002/mc.22538
8. Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A. Amit Persad,1,* Geetha Venkateswaran,1,* Li Hao,1 Maria E. Garcia,1 Jenny Yoon,1 Jaskiran Sidhu,1 and Sujata Persad1. Genes Cancer. 2016 Nov; 7(11-12): 368–382., doi: 10.18632/genesandcancer.128
9. Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of glioma cells by inactivating Wnt/β-catenin signaling. Qingxia Tao, Cuiying Wu, Ruxiang Xu, Lijun Niu, Jiazhen Qin, Ning Liu, Peng Zhang, Chong Wang. Cell and Tissue Research, 2017, doi:10.1007/s00441-017-2678-9.
10. BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury. Payel Bhanja, Andrew Norris, Pooja Gupta-Saraf, Andrew Hoover and Subhrajit Saha. Stem Cell Research & Therapy, vol. 9, no. 1, Feb. 2018, doi:10.1186/s13287-017-0763-3.
11. Direct Antioxidant Properties of Methotrexate: Inhibition of Malondialdehyde-Acetaldehyde-Protein Adduct Formation and Superoxide Scavenging. Matthew C. Zimmermana, Dahn L. Clemensb, c, Michael J. Duryeeb, Cleofes Sarmientoa, Andrew Chioub, Carlos D. Hunterb, Jun Tiana, Lynell W. Klassenb, c, James R. O’Dellb, c, Geoffrey M. Thieleb, c, Redox Biology,2017.07.018, doi: 10.1016/j.redox.2017.07.018
12. Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A. Amit Persad1,*, Geetha Venkateswaran1,*, Li Hao1, Maria E. Garcia1, Jenny Yoon1, Jaskiran Sidhu1 and Sujata Persad1.Genes & Cancer. January 30, 2017 . https://doi.org/10.18632/genesandcancer.128
13. Hypothermia augments stress response in mammalian cells. Eskla, Kattri-Liis, et al. Free Radical Biology and Medicine, 2018, doi:10.1016/j.freeradbiomed.2018.04.571.
14. A new ent-norabietant diterpenoid from roots of Euphorbia lathyris L. Yun, Young Sook, et al. Tetrahedron Letters, 2018, doi:10.1016/j.tetlet.2018.06.017.
15. Diversification of Bw4 Specificity and Recognition of a Nonclassical MHC Class I Molecule Implicated in Maternal–Fetal Tolerance by Killer Cell Ig-like Receptors of the Rhesus Macaque. Banerjee, Priyankana, et al. The Journal of Immunology, 2018, doi:10.4049/jimmunol.1800494.
16. P329G-CAR-J: a Novel Jurkat-NFAT-Based CAR-T Reporter System Recognizing the P329G Fc Mutation. Darowski, Diana, et al. Protein Engineering, Design and Selection, 2019, doi:10.1093/protein/gzz027.
17. Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy. Mayoux, Maud, et al. Science Translational Medicine Vol. 12, Issue 534, 2020. DOI: 10.1126/scitranslmed.aav7431
18. Innovative drinking water treatment techniques reduce the disinfection-induced oxidative stress and genotoxic activity. Lundqvist, Johan, et al. Water Research, vol. 155, 2019, pp. 182–192., doi:10.1016/j.watres.2019.02.052.
19. Discovery of a New STAT3 Inhibitor Acting on the Linker Domain. Koseki, Tatsuya, et al. Biological and Pharmaceutical Bulletin, vol. 42, no. 5, 2019, pp. 792–800., doi:10.1248/bpb.b18-00992.
20. An engineered ligand trap inhibits leukemia inhibitory factor as pancreatic cancer treatment strategy. Hunter, S.A., McIntosh, B.J., Shi, Y. et al. Commun Biol 4, 452 (2021). https://doi.org/10.1038/s42003-021-01928-2
21. Thiamine and Benfotiamine Protect Neuroblastoma Cells against Paraquat and β-Amyloid Toxicity by a Coenzyme-Independent Mechanism. Sambon, Margaux, et al. Heliyon, vol. 5, no. 5, 2019, doi:10.1016/j.heliyon.2019.e01710.
22. Vitale LA, He LZ, Thomas LJ, et al. Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy. Cancer Immunology, Immunotherapy : CII. 2020 May. DOI: 10.1007/s00262-020-02610-y.
23. Targeting the Liver‐Brain Axis with Hop‐Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice. Paraiso, I.L., Revel, J.S., Choi, J., Miranda, C.L., Lak, P., Kioussi, C., Bobe, G., Gombart, A.F., Raber, J., Maier, C.S. and Stevens, J.F. Mol. Nutr. Food Res. 2020, 2000341. https://doi.org/10.1002/mnfr.202000341
24. Glass-bottled drinking water: a time capsule to study the historic presence of hazardous chemicals using effect-based methods. Lundqvist, J., Persson, K.M. & Oskarsson, A. Environ Sci Eur 33, 34 (2021). https://doi.org/10.1186/s12302-021-00476-0
Transcription Factor Assays
TF Activation Profiling Plate Arrays
1. Differential Regulation Of Micrornas In Asthmatic Airways, Le W, Ghani M, Gutsche M, Wang W, Hwang PH, Upadhyay D, Am. J. Respir. Crit. Care Med., 2011 May;183: A2067.
2. Oncogenic KRAS impairs EGFR antibodies' efficiency by C/EBPβ-dependent suppression of EGFR expression, Derer S, Berger S, Schlaeth M, Schneider-Merck, T, Klausz K, Lohse S, Overdijk MB, Dechant M, Kellner C, Nagelmeier I, Scheel,, AH, Lammerts van Bueren JJ,van de Winkel JG, Parren PW, Peipp M, Valerius T. Neoplasia. 2012 Mar;14(3):190-205.
3. CRP promotes MMP-10 expression via c-Raf/MEK/ERK and JAK1/ERK pathways in cardiomyocytes, Cui C, Shi Q, Zhang X, Liu X, Bai Y, Li J, Liu S, Hu S, Wei Y. Cell Signal. 2012 Mar;24(3):810-8.
4. Identification of human nuclear factor 1 (NF-1) as a potential transcription factor which regulates the gene expression of Sulfotransferase isoform 1A1 (SULT1A1) in human breast cancer. Yao-Borengasser A, Yu X, Dhakal IB, Edavana VK, Williams S, and Kadlubar SA. Cancer Res., Apr 2012; 72: 1296.
5. Progesterone Regulation of Progesterone Receptor Membrane Component 1, (PGRMC1) Sumoylation and Transcriptional Activity in Spontaneously. Immortalized Granulosa Cells. Peluso JJ, Lodde V, Liu X. Endocrinology. 2012 Aug;153(8):3929-39
6. Mechanism for the induction of cell death in ONS. 76 medulloblastoma cells byZhangfei/CREB-ZF.Bodnarchuk TW, Napper S, Rapin. N, Misra V. J Neurooncol. 2012 Sep;109(3):485-501.
7. Novel compound SK-1009 suppresses interleukin-6 expression through modulation of activation of nuclear factor-kappaB pathway.Shimura M, Yamamoto M, Fujii G, Takahashi M, Komiya M, Noma N, Tanuma S, Yanaka A, Mutoh M. Biol Pharm Bull. 2012;35(12):2186-91. Epub 2012 Sep 27.
8. SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation. Toubal A, Clément K, Fan R, Ancel P, Pelloux V, Rouault C, Veyrie N, Hartemann A, Treuter E, Venteclef N. J Clin Invest. 2013 Jan 2;123(1):362-79.
9. Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke. Messier EM, Bahmed K, Tuder RM, Chu HW, Bowler RP, Kosmider B. Cell Death Dis. 2013 Apr 4;4:e573. doi: 10.1038/cddis.2013.96.
10. GC-Targeted C8-Linked Pyrrolobenzodiazepine-Biaryl Conjugates with Femtomolar in Vitro Cytotoxicity and in Vivo Antitumor Activity in Mouse Models. Rahman KM, Jackson PJ, James CH, Basu BP, Hartley JA, de la Fuente M, Schatzlein A, Robson M, Pedley RB, Pepper C, Fox KR, Howard PW, Thurston DE. J Med. Chem. 2013 Apr;56(7):2911-35.
11. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. Sharma A, Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC. J Biol Chem. 2013 Jun;288(25):18439-47.
12. Zinc regulation of transcriptional activity during retinoic acid-induced neuronal differentiation. Morris DR, Levenson CW. J Nutr Biochem. 2013 Sep. pii: S0955-2863(13)00126-5.
13. Effects Of Inhibition Of XPO1/CRM1-Dependent Nuclear Export By Selinexor (KPT 330), Alone and In Combination With Carfilzomib (CFZ), On Apoptosis and Autophagy In Multiple Myeloma (MM). Rosebeck S, Kandarpa M, Alonge MM, Jasielec J, Dytfeld D, Maxwell SP, Kraftson SJ, McCauley D, Shacham S, Kauffman M, Jakubowiak AJ. Blood. 2013 Nov;122(21) 279.
14. MYD88-independent growth and survival effects of Sp1 transactivation in Waldenstrom's macroglobulinemia. M Fulciniti, N Amodio, RL Bandi, M Munshi, G Yang. Blood. 2014- 01-550509v1
15. Combined inhibition of the proteasome and XPO1/CRM1-dependent nuclear export results in synergistic myeloma cell death via a novel mechanism of intracellular activation of caspase 10-dependent apoptosis. S Rosebeck, M Kandarpa, MM Alonge, A Mayampurath…
16. Novel Mechanism of Synergistic Myeloma Cell Death via Activation of Caspase 10-dependent Apoptosis by Carfilzomib and Selinexor.S Rosebeck, MM Alonge, M Kandarpa, A Mayampurath…
17. Myostatin regulates miR-431 expression via the Ras-Mek-Erk signaling pathway R Wu, H Li, T Li, Y Zhang, D Zhu - Biochemical and Biophysical Research,2015 Volume 461, Issue 2, 29 May 2015, Pages 224–229
18. Characterization of a Novel Mutation in SLC1A1 Associated with Schizophrenia. P Afshari, M Myles-Worsley, OS Cohen, J Tiobech… - Molecular Neuropsychiatry, 2015 Vol. 1, No. 3, 2015.
19. An Untargeted Proteomics and Systems-based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial Cells. KC Ravindra, WE Ho, C Cheng, LC Godoy, JS Wishnok, Chem. Res. Toxicol., DOI: 10.1021/acs.chemrestox.5b00105 , Publication Date (Web): September 4, 2015
20. Norcantharidin Suppresses Colon Cancer Cell Epithelial-Mesenchymal Transition by Inhibiting the αvβ6-ERK-Ets1 Signaling Pathway. Cheng Peng, Zequn Li, Zhengchuan Niu, Wei Niu, Zongquan Xu, Huijie Gao, Weibo Niu, JiaYong Wang, Zhaobin He, Chao Gao, Pengfei Lin, Michael Agrez, Zongli Zhang & Jun Niu Scientific Reports, 2016. Scientific Reports 6, Article number: 20500 (2016) doi:10.1038/srep20500
21. Functional and Activity Analysis of Cattle UCP3 Promoter with MRFs-Related Factors. W Chen, H Xu, X Chen, Z Liu, W Zhang, D Xia - International Journal of Molecular Science, 2016, Int. J. Mol. Sci. 2016, 17(5), 682; doi:10.3390/ijms17050682
22. The oncometabolite R-2-hydroxyglutarate activates NF-κB-dependent tumor-promoting stromal niche for acute myeloid leukemia cells. JY Chen, YS Lai, HJ Tsai, CC Kuo, BL Yen, SP Yeh, Scientific Reports 6, Article number: 32428 (2016) doi:10.1038/srep32428.
23. The oncometabolite R-2-hydroxyglutarate activates NF-κB-dependent tumor-promoting stromal niche for acute myeloid leukemia cells. JY Chen, YS Lai, HJ Tsai, CC Kuo, BL Yen, SP Yeh, Scientific Reports 6, Article number: 32428 (2016) doi:10.1038/srep32428.
24. A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer. PA Betancur, BJ Abraham, YY Yiu, SB Willingham, et al., Nature Communications 8, Article number: 14802 (2017) doi:10.1038/ncomms14802
25. The effect of brassinolide, a plant steroid hormone, on drug resistant small-cell lung carcinoma cells. D Sadava, SE Kane - Biochemical and Biophysical Research,Available online 25 August ,2017. https://doi.org/10.1016/j.bbrc.2017.08.094
26. Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis. BandanaShrestha, XiJiang, ShujunGe, DebayonPaul, PeterChianchiano, Joel S.Pachter. Neurobiology of Disease. Available online 24 August 2017.In Press, Accepted Manuscript. https://doi.org/10.1016/j.nbd.2017.08.010
27. HNF‑4α promotes multidrug resistance of gastric cancer cells through the modulation of cell apoptosis. Yubo Ma Xufu Wei Zhongjun Wu. Oncology Letters. September 28, 2017 https://doi.org/10.3892/ol.2017.7095
28. Plasmodium falciparum PfEMP1 modulates monocyte/macrophage transcription factor activation, and cytokine and chemokine responses. Natália Guimarães Sampaio, Emily Marie Erikssona, and Louis Schofield. Infection and Immunity, 2017, doi:10.1128/iai.00447-17.
29. AP4 positively regulates LAPTM4B to promote hepatocellular carcinoma growth and metastasis, whilst reducing chemotherapy sensitivity. Yue Meng, Lu Wang, Jianjun Xu, Qingyun Zhang. Molecular Oncology, 2018, doi:10.1002/1878-0261.12171.
30. Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer. Lee, Chia-Huei, et al. Cancers, vol. 11, no. 1, 2019, p. 63., doi:10.3390/cancers11010063.
31. A dimeric thymosin beta 4 with novel bio-activity protects post-ischemic cardiac function by accelerating vascular endothelial cell proliferation. Hao, Qiang, et al. International Journal of Cardiology, 2018, doi:10.1016/j.ijcard.2018.03.052.
32. PSME3 Promotes TGFB1 Secretion by Pancreatic Cancer Cells to Induce Pancreatic Stellate Cell Proliferation. Yu, Lianyuan, et al. Journal of Cancer, 2019; 10(9): 2128-2138. doi: 10.7150/jca.30235.
33. Tau Accumulation Activates STAT1 Triggering Memory Deficits via Suppressing NMDA Receptor Expression. Li, Xiaoguang, et al. 2018, doi:10.1101/437814.
34. Estrogen receptor α (ERα) indirectly induces transcription of human renal organic anion transporter 1 (OAT1). Euteneuer AM, Seeger-Nukpezah T, Nolte H, Henjakovic M. Physiol Rep. 2019 Nov;7(21):e14229. doi: 10.14814/phy2.14229. PMID: 31724834; PMCID: PMC6854606.
35. Early modulation of macrophage ROS-PPARγ-NF-κB signalling by sonodynamic therapy attenuates neointimal hyperplasia in rabbits. Yao, J., Zhao, X., Tan, F. et al. Sci Rep 10, 11638 (2020). https://doi.org/10.1038/s41598-020-68543-9
36. FOXA1 Regulation Turns Benzamide HDACi Treatment Effect-Specific in BC, Promoting NIS Gene-Mediated Targeted Radioiodine Therapy. Rathod M, Kelkar M, Valvi S, Salve G, De A. Mol Ther Oncolytics. 2020;19:93-104. Published 2020 Aug 29. doi:10.1016/j.omto.2020.08.015
37. LDOC1 Suppresses Microbe-Induced Production of IL-1β in Human Normal and Cancerous Oral Cells through the PI3K/Akt/GSK-3β Axis. Chia-Huei Lee, Pin-Feng Hung, Ko-Jiunn Liu, Hsuan-Lien Chung, Wen-Chan Yang, Kai-Cheng Hsu, Tsorng-Harn Fong,Hsiu-Jung Lo, Ya-Ping Chen, Ji-Rui Yang, and Ching-Yu Yen. Cancers 2020, 12(11), 3148; https://doi.org/10.3390/cancers12113148
38. Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis. Whasil Lee, Robert J. Nims, Alireza Savadipour, Qiaojuan Zhang, Holly A. Leddy, Fang Liu, Amy L. McNulty, Yong Chen, Farshid Guilak, Wolfgang B. Liedtke. Proceedings of the National Academy of Sciences Mar 2021, 118 (13) e2001611118; DOI: 10.1073/pnas.2001611118
39. Acetoacetate promotes muscle cell proliferation via the miR-133b/SRF axis through the Mek-Erk-MEF2 pathway. Ran Zhong, Renling Miao, Jiao Meng, Rimao Wu, Yong Zhang, Dahai Zhu. Acta Biochimica et Biophysica Sinica, 2021;, gmab079, https://doi.org/10.1093/abbs/gmab+A19:A97079
39. Ketkar, Harshada. “Abstract P222: Effect of western diet on pathophysiology and cardiac gene expression profile in human AT1 receptor over-expressing hypertensive transgenic mice.” Hypertension, vol. 80, no. Suppl_1, 11 Oct. 2023, pp. AP222–AP222, https://doi.org/10.1161/hyp.80.suppl_1.p222.
Promoter Binding TF Assays
1. Decoding Molecular Interplay between RUNX1 and FOXO3a Underlying the Pulsatile IGF1R Expression during Acquirement of Chemoresistance. Dhadve, Ajit C., Kishore Hari, Bharat Rekhi, Mohit Kumar Jolly, Abhijit De, and Pritha Ray. Biochimica Et Biophysica Acta (BBA) - Molecular Basis of Disease (2020): 165754.
2. Cross-talk between macrophages and atrial myocytes in atrial fibrillation. Zewei SunDongchen ZhouXudong XieShuai WangZhen WangWenting ZhaoHongfei XuLiangrong Zheng. Basic Research in Cardiology, 2016. DOI: 10.1007/s00395-016-0584-z
3. Snail-activated long non-coding RNA PCA3 up-regulates PRKD3 expression by miR-1261 sponging, thereby promotes invasion and migration of prostate cancer cells. JH He, BX Li, ZP Han, MX Zou, L Wang, YB Lv. Tumor Biology, 2016 Original Article First Online: 14 October 2016. DOI: 10.1007/s13277-016-5450-y
4. Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREB. P Jain, A Lavorgna, M Sehgal, L Gao, R Ginwala. Retrovirology, 2015Jain et al. Retrovirology(2015) 12:23 DOI 10.1186/s12977-015-0140-1
5. Functional and Activity Analysis of Cattle UCP3 Promoter with MRFs-Related Factors. Chen, W., Xu, H., Chen, X., Liu, Z., Zhang, W., & Xia, D. (2016). IJMS International Journal of Molecular Sciences, 17(5), 682. doi:10.3390/ijms17050682
6. Up-Regulation of CREG Expression by the Transcription Factor GATA1 Inhibits High Glucose- and High Palmitate-Induced Apoptosis in Human Umbilical Vein Endothelial Cells. Liu, Y., Tian, X., Li, Y., Liu, D., Liu, M., Zhang, X., Han, Y. (2016). PLOS ONE PLoS ONE,11(5). doi:10.1371/journal.pone.0154861
7. Characterization of the NLRC5 promoter in chicken: SNPs, regulatory elements and CpG islands. XM Guo, XP Liu, GB Chang, L Xu, YL Bi, HZ Wang DOI: 10.1111/age.12450 Animal Genetics, 2016
8. C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors
L von Elsner, S Hagemann, I Just, A Rohrbeck DOI: 10.1007/s00210-016-1270-2 Naunyn-Schmiedeberg's Archives of Pharmacology 2016
9. MGMT DNA repair gene promoter/enhancer haplotypes alter transcription factor binding and gene expression
M Xu, CE Cross, JT Speidel, SZ Abdel-Rahman doi:10.1007/s13402-016-0286-4 Cellular Oncology, 2016
10. Overexpression of Long Non-coding RNA MEG3 Inhibits Proliferation of Hepatocellular Carcinoma Huh7 Cells via Negative Modulation of miRNA-664. Jin-Hua He, Ze-Ping Han, Ji-Ming Liu, Jia-Bin Zhou, Mao-Xian Zou, Yu Bing Lv, Yu-Guang Li, Ming-Rong Cao. Journal of Cellular Biochemistry. 2017 April 4. doi: 10.1002/jcb.26018.
11. Ketkar, Harshada. “Abstract P222: Effect of western diet on pathophysiology and cardiac gene expression profile in human AT1 receptor over-expressing hypertensive transgenic mice.” Hypertension, vol. 80, no. Suppl_1, 11 Oct. 2023, pp. AP222–AP222, https://doi.org/10.1161/hyp.80.suppl_1.p222.
TF Interaction Plate Arrays
1. Identification and clinical significance of two divergent regulators in thoracic malignancy: miR-18a and RUNX1T1. He, Tian. [PhD Dissertion] Case Western Reserve University, 2021
EMSA
1. Piperlongumine exerts cytotoxic effects against cancer cells with mutant p53 proteins at least in part by restoring the biological functions of the tumor suppressor. D Basak, SR Punganuru, KS Srivenugopal . International Journal of Oncology . Published online on: Wednesday, February 3, 2016. Print ISSN: 1019-6439 Online ISSN:1791-2423
2. Selective killing of human breast cancer cells by the styryl lactone (R)-goniothalamin is mediated by glutathione conjugation, induction of oxidative stress and marked reactivation of the R175H mutant p53 protein . Punganuru, Surendra R, et al. Carcinogenesis, 2018, doi:10.1093/carcin/bgy093.
3. Enhanced Human Decidual Cell–Expressed FKBP51 May Promote Labor-Related Functional Progesterone Withdrawal.F Schatz, O Guzeloglu-Kayisli, M Basar, LF Buchwalder… - The American Journal of Pathology Availabe online 21 July 2015
4. Perineural Dexmedetomidine Attenuates Inflammation in Rat Sciatic Nerve via the NF-κB Pathway. Yan Huang †, Yi Lu †, Lei Zhang, Jia Yan, Jue Jiang and Hong Jiang * Int. J. Mol. Sci. 2014, 15, 4049-4059; doi:10.3390/ijms15034049
5. Spleen tyrosine kinase inhibition attenuates airway hyperresponsiveness and pollution-induced enhanced airway response in a chronic mouse model of asthma. Penton PC, Wang X, Amatullah H, Cooper J, Godri K, North ML, Khanna N, Scott JA, Chow CW. J Allergy Clin Immunol. 2013 Feb;131(2):512-20.e1-10.
6. Imipramine blue halts head and neck cancer invasion through promoting F-box and leucine-rich repeat protein 14-mediated Twist1 degradation.WH Yang, YH Su, WH Hsu, CC Wang, JL Arbiser. Oncogene,(10 August 2015) | doi:10.1038/onc.2015.291
7. CD97/ADGRE5 Inhibits LPS Induced NF-κB Activation through PPAR-γ Upregulation in Macrophages. Shuai Wang, Zewei Sun, Wenting Zhao, Zhen Wang, Mingjie Wu, Yanyun Pan, Hui Yan, and Jianhua Zhu. Mediators of Inflammation, 2016, Article ID 1605948
8. Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion. Marazioti, Antonia, et al. Nature Communications, vol. 9, no. 1, 2018, doi:10.1038/s41467-018-03051-z.
9. Methods to Quantify the NF-ΚB Pathway During Senescence. Zhang, Lei, et al. Methods in Molecular Biology Cellular Senescence, 2018, pp. 231–250., doi:10.1007/978-1-4939-8931-7_18.
10. Transcriptional Regulation of CCL2 by PARP1 Is a Driver for Invasiveness in Breast Cancer. Pranabananda Dutta, Kimberly Paico, Gabriela Gomez, Yanyuan Wu, Jaydutt V. Vadgama. Cancers 2020, 12(5), 1317; https://doi.org/10.3390/cancers12051317
11. Theophylline regulates inflammatory and neurotrophic factor signals in functional recovery after C2-hemisection in adult rats. Singh LP, Devi TS, Nantwi KD. Exp Neurol. 2012 Nov;238(1):79-88.
12. Protein kinase C inhibitor AEB071 targets ocular melanoma harboring GNAQ mutations via effects on the PKC/Erk1/2 and PKC/NF-κB pathways. Wu X, Li J, Zhu M, Fletcher JA, Hodi FS. Mol Cancer Ther. 2012 Sep;11(9):1905-14. doi: 10.1158/1535-7163.MCT-12-0121. Epub 2012 May 31.
13. Genetic deletion of CD36 enhances injury after acute neonatal stroke. Woo M, Wang X, Faustino JV, Derugin N, Wendland MF, Zhou P, Costantino Iadecola, Zinaida S. Vexler. Ann Neurol. 2012 Dec;72(6):961-70.
14. Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion. Marazioti, Antonia, et al. Nature Communications, vol. 9, no. 1, 2018, doi:10.1038/s41467-018-03051-z.
15. Glutamine-mediated Dual Regulation of Heat Shock Transcription Factor-1 Activation andExpression. Xue H, Slavov D, Wischmeyer PE.. J Biol Chem. 2012 Nov 23;287(48):40400-13.
16. The SxxSS motif of T-cell factor-4 isoforms modulates Wnt/β-catenin signal activation in hepatocellular carcinoma cells. Tomimaru Y, Koga H, Shin TH, Xu CQ, Wands JR, Kim M. Cancer Lett. 2013 Apr 2. pii: S0304-3835(13)00273-5. doi: 10.1016/j.canlet.2013.03.031. [Epub ahead of print]
17. 26S proteasome inhibitors inhibit dexamethasone-dependent increase of tyrosine aminotransferase and tryptophan 2,3-dioxygenase mRNA levels in primary cultured rat hepatocytes. Mizuho H, Masashi H, Youko N, Chieko S, Minako F, Taiichiro S, Toyohiko A, Nana K, Shingo N. Biophys Chem. 2012;3(4):348-356.
18. Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene.Donthamsetty S, Bhave VS, Kliment CS, Bowen WC, Mars WM, Bell AW, Stewart RE, Orr A, Wu C, Michalopoulos GK. Hepatology. 2011 Feb;53(2):587-95.
19. Effect of a Single-Nucleotide Polymorphism in the Cholecystokinin Type A Receptor Gene on Growth Traits in the Hinai-dori Chicken Breed. Rikimaru K, Takeda H, Uemoto Y, Komatsu M, Takahashi D, Suzuki K, Takahashi H J. Poult. Sci., 2013 50: 206-211.
20. Decreased levels of nuclear glucocorticoid receptor protein in the hippocampus of aged Long-Evans rats with cognitive impairment. Lee SY, Hwang YK, Yun HS, Han JS. Brain Res. 2012 Oct;1478:48-54.
21. TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy. Devi TS, Lee I, Hüttemann M, Kumar A, Nantwi KD, Singh LP. Exp Diabetes Res. 2012 ;2012:438238.
22. Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy. Devi TS, Hosoya KI, Terasaki T, Singh LP. Exp Cell Res. 2013 Jan 24. pii: S0014-4827(13)00019-0.
23. Nuclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I protect smooth muscle cells against oxidant-induced cell death. Xuwei Hou, Patricia Snarski, Yusuke Higashi, Tadashi Yoshida, Alexander Jurkevich, Patrick Delafontaine, and Sergiy Sukhanov. The FASEB Journal. 2017 April. DOI: 10.1096/fj.201601082R.
24. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Jiang, Xi, et al. Nature Communications, vol. 8, no. 1, 2017, doi:10.1038/s41467-017-02290-w.
25. Gong-Ping Liu, Xiao-Yue Hong, Hua-Li Wan et al. STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17, 07 May 2020, PREPRINT (Version 1) available at Research Square [+https://doi.org/10.21203/rs.3.rs-25793/v1+]
26. STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimer's disease animal model. Wan HL, Hong XY, Zhao ZH, et al. Theranostics. 2021;11(11):5511-5524. Published 2021 Mar 13. doi:10.7150/thno.56541
27. Tau Accumulation Activates STAT1 Triggering Memory Deficits via Suppressing NMDA Receptor Expression. Li, Xiaoguang, et al. 2018, doi:10.1101/437814.
28. Post-ischemic administration of 5-methoxyindole-2-carboxylic acid at the onset of reperfusion affords neuroprotection against stroke injury by preserving mitochondrial function and attenuating oxidative stress. Jinzi Wua, Zhen Jina, Xiaorong Yanga, b, Liang-Jun Yana. Biochemical and Biophysical Research Communications, 2018, doi:10.1016/j.bbrc.2018.02.106.
29. Involvement of pRb-E2F pathway in green tea extract-induced growth inhibition of human myeloid leukemia cells. Henry, Darrell, et al. Leukemia Research, 2019, doi:10.1016/j.leukres.2018.12.014.
30. An Essential Role for Perforin-2 in Type I IFN Signaling. Ryan McCormack, Richard Hunte, Eckhard R. Podack, Gregory V. Plano, Noula Shembade. The Journal of Immunology. March 11, 2020, ji1901013; DOI: 10.4049/jimmunol.1901013
31. Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis. Chatterjee, S., Yabaji, S.M., Rukhlenko, O.S., Bhattacharya, B., Waligurski, E., Vallavoju, N., Ray, S., Kholodenko, B.N., Brown, L.E., Beeler, A.B., Ivanov, A.R., Kobzik, L., Porco Jr., J.A., Kramnik, I., ISCIENCE (2021), doi: https://doi.org/10.1016/j.isci.2021.102845.
TF Filter Plate Assays
1. Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes. Li Y, Ma J, Zhu H, Singh M, Hill D, Greer PA, Arnold JM, Abel ED, Peng T. Diabetes. 2011 Nov;60(11):2985-94.
2. Melatonin MT1 receptor-induced transcriptional up-regulation of p27Kip1 in prostate cancer antiproliferation is mediated via inhibition of constitutively active nuclear factor kappa B (NF-κB): potential implications on prostate cancer chemoprevention and therapy. Shiu SY, Leung WY, Tam CW, Liu VW, Yao KM. J Pineal Res. 2012 Jun 20. doi: 10.1111/j.1600-079X.2012.01026.x. [Epub ahead of print]
3. Deficiency of Capn4 Gene Inhibits Nuclear Factor-κB (NF-κB) Protein Signaling/Inflammation and Reduces Remodeling after Myocardial Infarction. Ma J, Wei M, Wang Q, Li J, Wang H, Liu W, Lacefield JC, Greer PA, Karmazyn M, Fan GC, Peng T. J Biol Chem. 2012 Aug 10;287(33):27480-9.
4. Anti-inflammatory salicylate treatment alters the metabolic adaptations to lactation in dairy cattleAmerican Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2013.July 305(2) R110
5. Involvement of a chromatin modifier in response to mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell injury: Probably an indirect action via the regulation of NFκB/FasL circuitry. Chen S, Dong Y, Xu C, Jiang L, Chen Y, Jiang C, Hou W, Li W. Biochem Biophys Res Commun. 2013 Oct 8. pii: S0006-291X(13)01640-9.
6. Immunoglobulin light chains activate nuclear factor-B in renal epithelial cells through a Src-dependent mechanism. Ying WZ, Wang PX, Aaron KJ, Basnayake K, Sanders PW. Blood. 2011 Jan 27;117(4):1301-7.
7. In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5 (3). B Zhang, Y Shimada, J Kuroyanagi, M Ariyoshi . Biomaterials, 2015. Volume 52, June 2015, Pages 14–25
8. Repression of a chromatin modifier aggravates lipopolysaccharide-induced acute lung injury in mouseJia-kuan Chena, 1, Wen-chen Wanga, 1, Li Zangb, Jie Zhaoc, Wei Lic, Tao Jianga, ,Biochemical and Biophysical , 2016. doi:10.1016/j.bbrc.2016.02.043
9. Repression of a chromatin modifier aggravates lipopolysaccharide-induced acute lung injury in mouse J Chen, W Wang, L Zang, J Zhao, W Li, T Jiang. Biochemical and Biophysical Research Communications 2016. doi:10.1016/j.bbrc.2016.02.043
10. Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine Tao Yin, Zhengle Zhang, Bin Cao, Qingke Duan, Pengfei Shi, Hengqiang Zhao, Soriba Naby Camara, Qiang Shen, Chunyou Wang Oncotarget. 2016 May 11. doi: 10.18632/oncotarget.9293
11. Protective effects of tyrosol against LPS-induced acute lung injury via inhibiting NF-κB and AP-1 activation and activating the HO-1/Nrf2 Pathways. Wen-chen Wanga, Yan-min Xiaa , Bo Yangb, Xiang-ni Suc , Jia-kuan Chena, Wei Li, Tao Jiang. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 2017 DOI:10.1248/bpb.b16-00756
12. Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1 Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice. Zhang X, Lam KS, Ye H, Chung SK, Zhou M, Wang Y, Xu A. J Biol Chem. 2010 Oct 22;285(43):32869-77.
13. HIF-2α Suppresses p53 to Enhance the Stemness and Regenerative Potential of Human Embryonic Stem Cells. Das B, Bayat-Mokhtari R, Tsui M, Lotfi S, Tsuchida R, Felsher DW, Yeger H. Stem Cells. 2012 Aug;30(8):1685-1695.
14. Protective effects of tyrosol against LPS-induced acute lung injury via inhibiting NF-κB and AP-1 activation and activating the HO-1/Nrf2 Pathways. Wen-chen Wanga, Yan-min Xiaa , Bo Yangb, Xiang-ni Suc , Jia-kuan Chena, Wei Li, Tao Jiang. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 2017 DOI:10.1248/bpb.b16-00756
15. Upregulation of miRNA-155 expression by OxLDL in dendritic cells involves JAK1/2 kinase and transcription factors YY1 and MYB. H Yan, S Wang, Z Li, W Zhao, Z Wang, Z Sun, Y Pan. International Journal of Molecular Medicine , Print ISSN: 1107-3756. Online ISSN:1791-244X, Published online on: Friday, March 11, 2016
16. Sa1684 Common Food Additive Carrageenan Stimulates Wnt/β-Catenin Signaling Pathway in Colonic Epithelium by Inhibition of Nucleoredoxin Reduction.L Feferman, JK Tobacman. Nutrition and Cancer, 1–11, 2014, ISSN: 0163-5581 print / 1532-7914 online. DOI: 10.1080/01635581.2014.852228
17. CRP promotes MMP-10 expression via c-Raf/MEK/ERK and JAK1/ERK pathways in cardiomyocytes.Cui C, Shi Q, Zhang X, Liu X, Bai Y, Li J, Liu S, Hu S, Wei Y. Cell Signal. 2012 Mar;24(3):810-8.
18. Chondroitin sulfatases differentially regulate Wnt signaling in prostate stem cells through effects on SHP2, phospho-ERK1/2, and Dickkopf Wnt signaling pathway inhibitor (DKK3). Bhattacharyya, Sumit, et al. Oncotarget, 2017, doi:10.18632/oncotarget.22152.
19. Upregulation of MTA1 expression by human papillomavirus infection promotes CDDP resistance in cervical cancer cells via modulation of NF-κB/APOBEC3B cascade. Jia, Qiu-Ping, et al. Cancer Chemotherapy and Pharmacology, 2019, doi:10.1007/s00280-018-03766-2.
TF ELISA Kits
1. Antioxidant resveratrol restores renal sodium transport regulation in SHR, Apurva A. Javkhedkar, Anees A. Banday. Physiological Reports Published 24 November 2015 Vol. 3 no. e12618 DOI: 10.14814/phy2.12618
2. Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells. McNeill A, Magalhaes J, Shen C, Chau KY, Hughes D, Mehta A, Foltynie T, Cooper JM, Abramov AY, Gegg M, Schapira AH. Brain. 2014 Feb 25. [Epub ahead of print]
3. Curcumin decreased level of proinflammatory cytokines in monocyte cultures exposed to preeclamptic plasma by affecting the transcription factors NF-κB and PPAR-γ. B Rahardjo, E Widjajanto, H Sujuti, K Keman - Biomarkers and Genomic Medicine, 2014
4. The secondary bile acid, deoxycholate accelerates intestinal adenoma–adenocarcinoma sequence in Apcmin/+ mice through enhancing Wnt signaling. H Cao, S Luo, M Xu, Y Zhang, S Song, S Wang, X Kong… - Familial Cancer, 2014
5. Enhancing the Regenerative Effectiveness of Growth Factors by Local Inhibition of Interleukin-1 Receptor Signaling. Julier, Ziad, Rezvan Karami, Bhavana Nayer, Yen-Zhen Lu, Anthony J. Park, Kenta Maruyama, Gisela A. Kuhn, Ralph Müller, Shizuo Akira, and Mikaël M. Martino. Science Advances 6.24 (2020)
6. Melatonin Improves Brain Function in a Model of Chronic Gulf War Illness with Modulation of Oxidative Stress, NLRP3 Inflammasomes, and BDNF-ERK-CREB Pathway in the Hippocampus. Leelavathi N. Madhu, Maheedhar Kodali, Sahithi Attaluri, Bing Shuai, Laila Melissari, Xiaolan Rao, Ashok K. Shetty. Redox Biology, 2021, 101973, ISSN 2213-2317, https://doi.org/10.1016/j.redox.2021.101973.
TF Luciferase Reporter Vectors
1. Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL PS Souza, JP Madigan, JP Gilleta, K Kapoor… - Experimental Cell Research, 2015 Available online 19 June 2015.
2. EZH2-Mediated Inactivation of IFN-g-JAK-STAT1 Signaling Is an Effective Therapeutic Target in MYC-Driven Prostate Cancer.Zhen Ning,Wee,1,3 Zhimei Li,1 Puay Leng Lee,1 Shuet Theng Lee,1 ... Cell Reports Article.
3. Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice. Nobuharu Noma, Gen Fujii, Shingo Miyamoto, Masami Komiya, Ruri Nakanishi, Misato Shimura, Sei-ichi Tanuma and Michihiro Mutoh. International Journal of Molecular Sciences 18.4 (2017). doi: 10.3390/ijms18040851.
4. Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice. Nobuharu Noma, Gen Fujii, Shingo Miyamoto, Masami Komiya, Ruri Nakanishi, Misato Shimura, Sei-ichi Tanuma and Michihiro Mutoh. International Journal of Molecular Sciences 18.4 (2017). doi: 10.3390/ijms18040851.
5. Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis. Khan, Nazir M., et al. Free Radical Biology and Medicine, 2018, doi:10.1016/j.freeradbiomed.2018.01.013.
6. The Regulatory Function of miR-200c on Inflammatory and Cell-Cycle Associated Genes in SK-LMS-1, A Leiomyosarcoma Cell Line. TD Chuang, M Ho, O Khorram - Reproductive Sciences, 2014.
7. Analysis of CARD14 Polymorphisms in Pityriasis Rubra Pilaris: Activation of NF-κB. V Ratushny, GP Smith – analysis. Journal of Investigative Dermatology(2015)135,1905–1908; doi:10.1038/jid.2015.65; published online 2 April 2015.
8. Angiotensin II Differentially Regulates Morg1 Expression in Kidney Cells.Bondeva T, Heinzig J, Franke S, Wolf G.Am J Nephrol. 2012;35(5):442-55. doi: 10.1159/000337922. Epub 2012 Apr 27.
9. Endometrial miR-200c is Altered During Transformation into Cancerous States and Targets the Expression of ZEBs, VEGFA, FLT1, IKKβ, KLF9, and FBLN5. Panda H, Pelakh L, Chuang TD, Luo X, Bukulmez O, Chegini N. Reprod Sci. 2012 Aug;19(8):786-96.
10. Evidence for a genomic mechanism of action for progesterone receptor membrane component-1. Peluso JJ, Decerbo J, Lodde V. Steroids. 2012 Aug;77(10):1007-12.
11. The Nrf2 activator, tBHQ, differentially affects early events following stimulation of Jurkat cells. Toxicol. Sci. (2013) doi: 10.1093/toxsci/kft172 First published online: August 14, 2013.
12. Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cell. A Infante, A Gago, GR de Eguino, T Calvo-Fernández… - AGING, 2014.
13. Double Suppression of the Gα Protein Activity by RGS Proteins. Lin C, Koval A, Tishchenko S, Gabdulkhakov A, Tin U, Solis GP, Katanaev VL. Mol Cell. 2014 Feb 20;53(4):663-71.
14. Dicer Knockdown Inhibits Endothelial Cell Tumor Growth via MicroRNA 21a-3p Targeting of Nox-4. Gordillo GM, Biswas A, Khanna S, Pan X, Sinha M, Roy S, Sen CK. J Biol Chem. 2014 Feb 4.
15. Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and MicroRNA Profiling Study. Dong H, You SH, Williams A, Wade MG, Yauk CL, Thomas Zoeller R. Cereb Cortex. 2014 Feb 7.
16. Endothelin-1 Induces a Glycolytic Switch in Pulmonary Arterial Endothelial Cells via the Mitochondrial Translocation of Endothelial NO Synthase. Sun X, Kumar S, Sharma S, Aggarwal S, Lu Q, Gross C, Rafikova O, Lee SG, Dasarathy S, Hou Y, Meadows ML, Han W, Su Y, Fineman JR, Black SM. Am J Respir Cell Mol Biol. 2014 Jan 6.
17. Common food additive carrageenan stimulates Wnt/ β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction. Bhattacharyya S, Feferman L, Borthakur S, Tobacman JK. Nutr Cancer. 2014 ;66(1):117-27.
18. Effects of all-trans retinoic acid, retinol, and β-carotene on murine macrophage activity. Lo HM, Wang SW, Chen CL, Wu PH, Wu WB. Food Funct. 2014 Jan;5(1):140-8.
19. Selectively Targeting Prostate Cancer with Antiandrogen Equipped Histone Deacetylase Inhibitors. Gryder BE, Akbashev MJ, Rood MK, Raftery ED, Meyers WM, Dillard P, Khan S, Oyelere AK. ACS Chem Biol. 2013 Sep 20. [Epub ahead of print]
20. Advanced glycated end products affect HIF- transcriptional activity in renal cells. Bondeva T, Heinzig J, Ruhe C, Wolf G. Mol Endocrinol. 2013 Sep 12. [Epub ahead of print]
21. Obesity induced a leptin-Notch signaling axis in breast cancer. Battle M, Gillespie C, Quarshie A, Lanier V, Harmon T, Wilson K, Torroella-Kouri M, Gonzalez-Perez RR. Int J Cancer. 2013 Sep 30. [Epub ahead of print]
22. The carotenoid lutein enhances matrix metalloproteinase-9 production and phagocytosis through intracellular ROS generation and ERK1/2, p38 MAPK, and RARβ activation in murine macrophages. Lo HM, Chen CL, Yang CM, Wu PH, Tsou CJ, Chiang KW, Wu WB. J Leukoc Biol. 2013 May;93(5):723-35.
23. The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R. Cell 2012 41615;151(6):1185-99.
24. Influences of flavones on cell viability and cAMP-dependent steroidogenic gene regulation in MA-10 Leydig cells. M Cormier, F Ghouili, P Roumaud, W Bauer… - Cell Biology and Toxicology ,28 April 2017;DOI: 10.1007/s10565-017-9395-8.
25. Glucocorticoids regulate MiR-29c levels in vascular smooth muscle cells through transcriptional and epigenetic mechanisms. TD Chuang, O Khorram - Life Sciences, Volume 186, 1 October 2017, Pages 87-91. https://doi.org/10.1016/j.lfs.2017.08.007
26. Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A. Amit Persad1,*, Geetha Venkateswaran1,*, Li Hao1, Maria E. Garcia1, Jenny Yoon1, Jaskiran Sidhu1 and Sujata Persad1.Genes & Cancer. January 30, 2017 . https://doi.org/10.18632/genesandcancer.128
27. ATF2 promotes urothelial cancer outgrowth via cooperation with androgen receptor signaling. Inoue, Satoshi, et al. Endocrine Connections, 2018, pp. 1397–1408., doi:10.1530/ec-18-0364.
28. PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice. Okamura, Maya and Shizu, Ryota and Abe, Taiki and Kodama, Susumu and Hosaka, Takuomi and Sasaki, Takamitsu and Yoshinari, Kouichi. Cells, 2020;10(9):2296, ISSN: 2073-4409, DOI: 10.3390/cells9102296
29. Platonin, a Cyanine Photosensitizing Dye, Ameliorates Inflammatory Responses in Vascular Smooth Muscle Cells by Modulating Inflammatory Transcription Factors. Chiu, C.-W.; Yang, C.-H.; Tsai, J.-H.; Hsieh, C.-Y.; Huang, S.-Y. Applied Sciences. 2021; 11(3):1130. https://doi.org/10.3390/app11031130.
30. Tau Accumulation Activates STAT1 Triggering Memory Deficits via Suppressing NMDA Receptor Expression. Li, Xiaoguang, et al. 2018, doi:10.1101/437814.
Cytokines ELISA
Cytokine ELISA Plate Arrays
1. ALDH3A1 Overexpression in Melanoma and Lung Tumors Drives Cancer Stem Cell Expansion, Impairing Immune Surveillance through Enhanced PD-L1 Output. Terzuoli, Erika, et al. Cancers, vol. 11, no. 12, 2019, p. 1963., doi:10.3390/cancers11121963.
2. Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cassetta, Luca, et al. Cancer Cell, 2019, doi:10.1016/j.ccell.2019.02.009.
3. Adipose tissue extract shows potential for wound healing: in vitro proliferation and migration of cell types contributing to wound healing in the presence of adipose tissue preparation and platelet rich plasma. Jenny F. López, Jertta-Riina Sarkanen, Outi Huttala, Ilkka S. Kaartinen, Hannu O. Kuokkanen, Timo Ylikomi. Cytotechnology, 2018, doi:10.1007/s10616-018-0211-y.
4. Priming hMSCs with a putative anti-cancer compound, myrtucommulone-a: a way to harness hMSC cytokine expression via modulating PI3K/Akt pathway? B Iskender, K Izgi, C Sakalar, H Canatan . Tumor Biology, First online: 03 September 2015.
5. SG15 counteracts Listeria monocytogenes infection.L Radoshevich, F Impens, D Ribet, JJ Quereda.eLife. 2015; 4: e06848.Published online 2015 Aug 11. doi: 10.7554/eLife.06848.
6. Suppression of SERPINA1-albumin Complex Formation by Galectin-3 Overexpression Leads to Paracrine Growth Promotion of Chronic Myelogenous Leukemia Cells. Nakayama, Ryuko, Junya Kuroda, Nobuko Taniyama, Mio Yamamoto-Sugitani, Sayori Wada, Miki Kiyota, Shinsuke Mizutani, Yoshiaki Chinen, Yosuke Matsumoto, Hisao Nagoshi, Yuji Shimura, Tsutomu Kobayashi, Shigeo Horiike, Kenji Sato, and Masafumi Taniwaki. Leukemia Research 38.1 (2014): 103-08. Print.
7. Human Urine-Derived Stem Cells Alone or Genetically-Modified with FGF2 Improve Type 2 Diabetic Erectile Dysfunction in a Rat Model. B Ouyang, X Sun, D Han, S Chen, B Yao, Y Gao, J Bian etc. PLOS ONE, 2014 DOI:10.1371/journal.pone.0092825.
8. Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis. Wen F, Shen A, Choi A, Gerner EW, Shi J. Cancer Res. 2013 Jul 15;73(14):4256-66. doi: 10.1158/0008-5472.CAN-12-3287. Epub 2013 May 30.
9. Radiotherapy-induced plasma cytokine changes and skin toxicity in breast cancer patients. Liu Z, Thomas V, Wright J, Takita C, Poitevien M, Abreu-Molnar D, Zhao W, Reis I, and Hu J. Cancer Res., 2012 Apr;72: 4352.
10. Normal Mesothelial Cell Lines Newly Derived from Human Pleural Biopsy Explants. N Pruett, A Singh, A Shankar, DS Schrump, CD Hoang. American Journal of Physiology-Lung Cellular and Molecular Physiology, July 2020, https://doi.org/10.1152/ajplung.00141.2020
11. Hartley, A., Wang, B., Mundade, R. et al. PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer. Sci Rep 10, 15934 (2020). https://doi.org/10.1038/s41598-020-72942-3
12. EGR1 is a gatekeeper of inflammatory enhancers in human macrophages. Trizzino M, Zucco A, Deliard S, Wang F, Barbieri E, Veglia F, Gabrilovich D, Gardini A. Science Advances. 2021 Jan;7(3):eaaz8836. DOI: 10.1126/sciadv.aaz8836
13. 3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells. Kang-Yun Lu, Shinn-Zong Lin, Kingsley Theras Primus Dass, Wei-Ju Lin, Shih-Ping Liu, Horng-Jyh Harn. Biomedicine & Pharmacotherapy, Volume 139, 2021, 111687, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2021.111687.
14. Physoxia alters human mesenchymal stem cell secretome. Merkhan MM, Shephard MT, Forsyth NR. Journal of Tissue Engineering. January 2021. doi:10.1177/20417314211056132
15. Electrical stimulation with periodic alternating intervals stimulates neuronal cells to produce neurotrophins and cytokines through activation of mitogen-activated protein kinase pathways. K Yamamoto, T Yamamoto, K Honjo, H Ichioka. European Journal of Oral Sciences. Article first published online: 29 OCT 2015. DOI: 10.1111/eos.12224.
16. Parasites alter the pathological phenotype of lupus nephritis. K Miyake, K Adachi, M Watanabe, Y Sasatomi etc. Autoimmunity. 2014 Dec;47(8):538-47. doi: 10.3109/08916934.2014.929669. Epub 2014 Jun 24.
17. No requirement of interlukine-1 for long-term potentiation in the anterior cingulate cortex of adult mice. Lu, Jing-Shan, et al. Molecular Pain, vol. 14, 2018, p. 174480691876579., doi:10.1177/1744806918765799.
18. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease. Yun, Seung Pil, et al. Nature Medicine, 2018, doi:10.1038/s41591-018-0051-5.
19. Compromised Astrocyte Function and Survival Negatively Impact Neurons in Infantile Neuronal Ceroid Lipofuscinosis. Lange, Jenny, et al. Acta Neuropathologica Communications, vol. 6, no. 1, 2018, doi:10.1186/s40478-018-0575-4.
20. Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. Harun-Or-Rashid, Mohammad, and Denise M. Inman. Journal of Neuroinflammation, vol. 15, no. 1, 2018, doi:10.1186/s12974-018-1346-7.
21. Mine-site derived particulate matter exposure exacerbates neurological and pulmonary inflammatory outcomes in an autoimmune mouse model. Alexis Wilson, Carmen A. Velasco, Guy W. Herbert, Selita N. Lucas, Bethany N. Sanchez, José M. Cerrato, Michael Spilde, Quan-Zhen Li, Matthew J. Campen & Katherine E. Zychowski (2021), Journal of Toxicology and Environmental Health, Part A, DOI: 10.1080/15287394.2021.1891488
22. 3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells. Kang-Yun Lu, Shinn-Zong Lin, Kingsley Theras Primus Dass, Wei-Ju Lin, Shih-Ping Liu, Horng-Jyh Harn. Biomedicine & Pharmacotherapy, Volume 139, 2021, 111687, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2021.111687.
23. Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer's disease. CE Hanzel, A Pichet Binette, LSB Pimentel, MF Iulita. Neurobiol Aging. 2014 Oct;35(10):2249-62. doi: 10.1016/j.neurobiolaging.2014.03.026. Epub 2014 Mar 28.
24. Prenatal inhibition of the tryptophan-kynurenine pathway alters synaptic plasticity and protein expression in the rat hippocampus. Forrest CM, Khalil OS, Pisar M, Darlington LG, Stone TW. Brain Res. 2013 Apr;1504:1-15.
25. Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease. Laura R. Marksa, Bruce A. Davidsonb,c, Paul R. Knighta,b,c,d, Anders P. Hakanssona,d,e 23 July 2013 mBio vol. 4 no. 4 e00438-13. 23 July 2013 mBio vol. 4 no. 4 e00438-13.
26. Evaluation of the efficacy of cell and micrograft transplantation for full-thickness wound healing. Carla R. Kruse, Dharaniya Sakthivel, Indranil Sinha, Douglas Helm, Jens A. Sørensen, Elof Eriksson, Kristo Nuutila. Journal of Surgical Research, vol. 227, 2018, pp. 35–43., doi:10.1016/j.jss.2018.02.004.
27. Effects of intravenous and intranasal P-glycoprotein modulation on the blood-brain barrier in young and aging rats. Bors, L. A., & Franciska, V. D. E. [PhD Dissertation] Pázmány Péter Catholic University, 2020
28. Effects of RSO-021 on cytokine profiles of malignant pleural effusions from patients enrolled in the MITOPE phase 1/2 clinical trial. Terri Messier, Molly Scotland, George Naumov, Sean Dulloo, Dean Fennell, Brian Cunniff. Mol Cancer Ther 1 December 2023; 22 (12_Supplement): B022.
Human Cytokine ELISA Strips
1. Mesenchymal Stem Cell-derived Magnetic Extracellular Nanovesicles for Targeting and Treatment of Ischemic Stroke. Kim, Han Young, Tae Jung Kim, Lami Kang, Young-Ju Kim, Min Kyoung Kang, Jonghoon Kim, Ju Hee Ryu, Taeghwan Hyeon, Byung-Woo Yoon, Sang-Bae Ko, and Byung-Soo Kim. Biomaterials (2020): 119942.
2. Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: tissue engineering implications. TM Fortunato, C Beltrami, C Emanueli, A Paul, G Pula - Scientific Reports, 2016, Article number: 25326 (2016)doi:10.1038/srep25326
3. Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy. Piwen WangEmail author, Susanne M. Henning, Clara E. Magyar, Yahya Elshimali, David Heber and Jaydutt V. Vadgama. Journal of Experimental & Clinical Cancer Research201635:73 DOI: 10.1186/s13046-016-0351-x
4. Aging Impairs VEGF-Mediated, Androgen-Dependent Regulation Of Angiogenesis. Laura Lecce1,2,*, Yuen Ting Lam1,2,*, Laura A. Lindsay2, Sui Ching Yuen1,2, Philippa J. L. Simpson1,2, David J. Handelsman2,3, andMartin K. C. Ng1,2,4 Mol Endorinl. 2014 Jul24 :,e20131405.
5. Neuronal over-expression of ACE2 protects brain from ischemia-induced damage. Chen J, Zhao Y, Chen S, Wang J, Xiao X, Ma X, Penchikala M, Xia H, Lazartigues E, Zhao B, Chen Y. Neuropharmacology. 2014 41654;79C:550-558.
6. A Novel Multiparameter In Vitro Model of Three-Dimensional Cell Ingress Into Scaffolds for Dermal Reconstruction to Predict In Vivo Outcome. García-Gareta E, Ravindran N, Sharma V, Samizadeh S, Dye JF. Biores Open Access. 2013 41974;2(6):412-20.
7. Hypoxia differentially regulates arterial and venous smooth muscle cell proliferation via PDGFR-β and VEGFR-2 expression. Chanakira A, Dutta R, Charboneau R, Barke R, Santilli. SM, Roy S. Am J Physiol Heart Circ Physiol., 2012 Mar;302:H1173-H1184.
8. Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in Mol Brain. 2012 Jun 9;5(1):22. Forrest CM, Khalil OS, Pisar M, Smith RA, Darlington LG, Stone TW. offspring.
9. Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus. Alcendor DJ, Charest AM, Zhu WQ, Vigil HE, Knobel SM. Neuroinflammation., 2012 May 18;9:95.
10. Cancer biomarkers detection using 3D microstructured protein chip: Implementation of customized multiplex immunoassay. Yanga Z, Chevolota Y, Ataman-Önalb Y, Choquet-Kastylevskyb G, Souteyranda E, Laurenceaua E. Sens Actuators B Chem., Available online 28 November 2011
11. Computational Protein Design to Reengineer Stromal Cell–Derived Factor-1α Generates an Effective and Translatable Angiogenic Polypeptide Analog. Hiesinger W, Perez-Aguilar JM, Atluri P, Marotta NA, Frederick JR, Fitzpatrick JR 3rd, McCormick RC, Muenzer JR, Yang EC, Levit RD, Yuan LJ, Macarthur JW,Saven JG, Woo YJ. Circulation., 2011 Sep;124:S18-S26.
12. Antisense oligonucleotide suppression of serum amyloid A reduces amyloid deposition in mice with AA amyloidosis. Kluve-Beckerman B, Hardwick J, Du L, Benson MD, Monia BP, Watt A, Crooke RM, Mullick A. Amyloid., 2011 Sep;18:136-146.
13. Extracellular signal regulated kinase 5: A potential therapeutic target formalignant mesotheliomas. Shukla A, Miller JM, Cason C, Sayan M, Macpherson MB, Beuschel SL, Hillegass JM, Vacek PM, Pass H,Mossman BT. Clin Cancer Res., 2013 Apr;19(8):2071-83.
14. Hypoxia differentially regulates arterial and venous smooth muscle cell proliferation via PDGFR-β and VEGFR-2 expression. Chanakira A, Dutta R, Charboneau R, Barke R, Santilli SM, Roy S. Am J Physiol Heart Circ Physiol., 2012 Mar;302:H1173-H1184.
15. miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo. Shin KK, Lee AL, Kim JY, Lee SY, Bae YC, Jung JS. Biochem Biophys Res Commun., 2012 Jun;422(4):633-8.
16. In vitro endothelial cell response to ionic dissolution products from boron-doped bioactive glass in the SiO2-CaO-P2O5-Na2O system . LAH Durand, A Góngora, JMP López, AR Boccaccini. Journal of Materials Chemistry B, 2014,2, 7620-7630 DOI: 10.1039/C4TB01043D
17. Synthesis and Evaluation of New 4-Chloro-2-(3-chloro-4-fluorophenyl)-5-(aliphatic/cyclic saturated amino)pyridazin-3(2H)-one Derivatives as Anticancer, Antiangiogenic, and Antioxidant Agents. VT Kamble, AS Sawant, SS Sawant, PM Pisal. Archiv der Pharmazie Volume 348, Issue 5, pages 338–346, May 2015
18. Adipose tissue extract shows potential for wound healing: in vitro proliferation and migration of cell types contributing to wound healing in the presence of adipose tissue preparation and platelet rich plasma. Jenny F. López, Jertta-Riina Sarkanen, Outi Huttala, Ilkka S. Kaartinen, Hannu O. Kuokkanen, Timo Ylikomi. Cytotechnology, 2018, doi:10.1007/s10616-018-0211-y.
19. Osteocyte apoptosis is mechanically regulated and induces angiogenesis in vitro. Cheung WY, Liu C, Tonelli-Zasarsky RM, Simmons CA, You L. J Orthop Res. 2011 Apr;29(4):523-30.
20. A Novel Function of p38-Regulated/Activated Kinase in Endothelial Cell Migration and Tumor Angiogenesis. Yoshizuka N, Chen RM, Xu Z, Liao R, Hong L, Hu WY, Yu G, Han J, Chen L, Sun P. Mol. Cell. Biol., 2012 Feb; 32:606-618.
21. NF1 gene silencing induces upregulation of VEGF expression in both Schwann and non-Schwann cells.
Kawachi Y, Maruyama H, Ishitsuka Y, Fujisawa Y, Furuta J, Nakamura Y, Ichikawa E, Furumura M, Otsuka F. Exp Dermatol., 2013 Apr;22(4):262-265. doi: 10.1111/exd.12115. Epub 2013 Mar 26.
22. Modulation of Matrix Metalloprotease-2 Levels by Mechanical Loading of Three-Dimensional Mesenchymal Stem Cell Constructs: Impact on In Vitro Tube Formation. Glaeser. , Geissler S, Ode A, Schipp CJ, Matziolis G, Taylor WR, Knaus P, Perka C, Duda GN, Kasper G. Tissue Eng Part A. 2010 Oct;16(10):3139-48.
23. A Novel Function of p38-Regulated/Activated Kinase in Endothelial Cell Migration and Tumor Angiogenesis. Yoshizuka N, Chen RM, Xu Z, Liao R, Hong L, Hu WY, Yu G, Han J, Chen L, Sun P. Mol. Cell. Biol., 2012 Feb;32:606-618.
24. miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo. Shin KK, Lee AL, Kim JY, Lee SY, Bae YC, Jung JS. Biochem Biophys Res Commun., 2012 Jun;422(4):633-8.
25. Influence of heirloom tomato polyphenol extracts on expression of inflammation genes in bovine. Gyenai K, Mikiashvili N, Ismail H, Worku M. Am J Animal Vet Sci 2012;7(3):126-135.
26. Functional effects of nanoparticle exposure on Calu-3 airway epithelial cells. Banga A, Witzmann FA, Petrache HI, Blazer-Yost BL. Cell Physiol Biochem. 2012;29(1-2):197-212.
27. Dipyridamole prevents triple-negative breast-cancer progression. Spano D, Marshall JC, Marino N, De Martino D, Romano A, Scoppettuolo MN, Bello AM, Di Dato V, Navas L, De Vita G, Medaglia C, Steeg PS, Zollo M. Clin Exp Metastasis., 2013 Jan;30(1):47-68.
28. Pituitary tumor transforming gene 1 induces tumor necrosis factor-α production from keratinocytes: implication for involvement in the pathophysiology of psoriasis. Ishitsuka Y, Kawachi Y, Maruyama H, Taguchi S, Fujisawa Y, Furuta J, Nakamura Y, Ishii Y, Otsuka F. J Invest Dermatol. 2013 Nov;133(11):2566-75.
29. Intercellular communication of cellular stress monitored by -H2AX induction, Dickey JS, Baird BJ, Redon CE, Sokolov MV, Sedelnikova OA, Bonner WM. Carcinogenesis., 2009 Oct;30:1686-1695.
30. Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis. Poehlmann A, Reissig K, Just A, Walluscheck D, Hartig R, Schinlauer A, Lessel W, Guenther T, Silver A, Steinberg P, Roessner A. J Cell Mol Med., 2013 Jun doi: 10.1111/jcmm.12079. [Epub ahead of print].
31. Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus. Alcendor DJ, Charest AM, Zhu WQ, Vigil HE, Knobel SM. Neuroinflammation., 2012 May;9:95.
32. A 24-week dietary and physical activity lifestyle intervention reduces hepatic >insulin resistance in the obese with chronic hepatitis C. Pattullo V, Duarte-Rojo A, Soliman W, Vargas-Vorackova F, Sockalingam S, Fantus IG, Allard J, Heathcote J. Liver Int. 2013 Mar;33(3):410-9.
33. Amelioration of Myocardial Ischemia/reperfusion Injury by L-carnitine Via Down Regulation of the Inflammatory Response and Apoptosis.N Hadi, F Al-Amran, M Yousif, M Alrekabi - 2014 EXPERIMENTAL & CLINICAL CARDIOLOGY
34. Extracellular signal regulated kinase 5: A potential therapeutic target formalignant mesotheliomas. Shukla A, Miller JM, Cason C, Sayan M, Macpherson MB, Beuschel SL, Hillegass JM, Vacek PM, Pass H,Mossman BT. Clin Cancer Res., 2013 Apr;19(8):2071-83.
35. Carrageenan-induced Colonic Inflammation is Reduced in Bcl10-Null Mice and Increased in IL-10 Deficient Mice. Bhattacharyya S, Xue L, Devkota S, Chang E, Morris S, Tobacman JK. Mediators Inflamm., 2013;2013:397642.
36. Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis. Poehlmann A, Reissig K, Just A, Walluscheck D, Hartig R, Schinlauer A, Lessel W, Guenther T, Silver A, Steinberg P, Roessner A. J Cell Mol Med., 2013 Jun doi: 10.1111/jcmm.12079. [Epub ahead of print].
37. Circulating Mir-320a Promotes Immunosuppressive Macrophages M2 Phenotype Associated with Lung Cancer Risk. Fortunato, Orazio, et al. International Journal of Cancer, 2018, doi:10.1002/ijc.31988.
38. Synthesis and Evaluation of a Novel Series of 6-Bromo-1-Cyclopentyl-1H-Indazole-4-Carboxylic Acid-Substituted Amide Derivatives as Anticancer, Antiangiogenic, and Antioxidant Agents. Sawant, Ajay S., et al. Medicinal Chemistry Research, 2019, doi:10.1007/s00044-019-02454-x.
39. Reseeding Endothelial Cells with Fibroblasts to Improve the Re-Endothelialization of Pancreatic Acellular Scaffolds. Xu, Liancheng, et al. Journal of Materials Science: Materials in Medicine, vol. 30, no. 7, 2019, doi:10.1007/s10856-019-6287-x.
40. Perinatal High-Fat Diet and Bisphenol A: Effects on Behavior and Gene Expression in the Medial Prefrontal Cortex. Wise, Leslie M., et al. Developmental Neuroscience, 2018, pp. 1–16., doi:10.1159/000494879.
Mouse Cytokine ELISA Strips
1. Integrative proteomics and targeted transcriptomics analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular dysfunction.O Azimzadeh, W Sievert, H Sarioglu, J Merl-Pham. J Proteome Res. 2015 Feb 6;14(2):1203-19. doi: 10.1021/pr501141b. Epub 2015 Jan 29.
2. The immune-enhancing effect of the Cronobacter sakazakii ES2 phage results in the activation of nuclear factor-κB and dendritic cell maturation via the activation of IL-12 p40 in the mouse bone marrow. An TW, Kim SJ, Lee YD, Park JH, Chang H. Immunol Lett. 2014 Jan-Feb;157(1-2):1-8.
3. Effect of carbon nanoparticles on renal epithelial cell structure, barrier function, and protein expression. Blazer-Yost BL, Banga A, Amos A, Chernoff E, Lai X, Li C, Mitra S, Witzmann FA. Nanotoxicology, 2011 Sep, 5: 354-371. doi: 10.3109/17435390.2010.514076. Epub 2010 Nov 10.
4. The immune-enhancing effect of the Cronobacter sakazakii ES2 phage results in the activation of nuclear factor-κB and dendritic cell maturation via the activation of IL-12 p40 in the mouse bone marrow. An TW, Kim SJ, Lee YD, Park JH, Chang H. Immunol Lett. 2014 Jan-Feb;157(1-2):1-8.
5. Effect of carbon nanoparticles on renal epithelial cell structure, barrier function, and protein expression. Blazer-Yost BL, Banga A, Amos A, Chernoff E, Lai X, Li C, Mitra S, Witzmann FA. Nanotoxicology, 2011 Sep, 5: 354-371. doi: 10.3109/17435390.2010.514076. Epub 2010 Nov 10.
6. Dipyridamole prevents triple-negative breast-cancer progression, Daniela Spano, Jean-Claude Marshall, Natascia Marino, Daniela De Martino, Alessia Romano, Spano D, Marshall JC, Marino N, De Martino D, Romano A, Scoppettuolo MN, Bello AM, Di Dato V, Navas L, De Vita G, Medaglia C, Steeg PS, Zollo M. Clin Exp Metastasis. 2013 Jan;30(1):47-68. doi: 10.1007/s10585-012-9506-0. Epub 2012 Jul 4.
7. Computational Protein Design to Reengineer Stromal Cell–Derived Factor-1α Generates an Effective and Translatable Angiogenic Polypeptide Analog. Hiesinger W, Perez-Aguilar JM, Atluri P, Marotta NA, Frederick JR, Fitzpatrick JR 3rd, McCormick RC, Muenzer JR, Yang EC, Levit RD, Yuan LJ, Macarthur JW,Saven JG, Woo YJ. Circulation., 2012 Sep;124:S18-S26.
8. Stem Cells and Cardiac Repair. Sadia Mohsin, Daniele Avitabile, and Mohsin Khan. Stem Cells International Volume 2015, Article ID 153627, 2 pages.
9. Chemopreventive and immunomodulatory effects of Murraya koenigii aqueous extract on 4T1 breast cancer cell-challenged mice. SK Yeap, N Abu, NE Mohamad, BK Beh, WY Ho, BMC Complementary and Alternative Medicine 2015, 15:306 doi:10.1186/s12906-015-0832-z.
10. Osteocyte apoptosis is mechanically regulated and induces angiogenesis in vitro. Cheung WY, Liu C, Tonelli-Zasarsky RM, Simmons CA, You L. J Orthop Res. 2011 Apr;29(4):523-30.
11. A Novel Function of p38-Regulated/Activated Kinase in Endothelial Cell Migration and Tumor Angiogenesis. Yoshizuka N, Chen RM, Xu Z, Liao R, Hong L, Hu WY, Yu G, Han J, Chen L, Sun P. Mol. Cell. Biol., 2012 Feb; 32:606-618.
12. NF1 gene silencing induces upregulation of VEGF expression in both Schwann and non-Schwann cells. Kawachi Y, Maruyama H, Ishitsuka Y, Fujisawa Y, Furuta J, Nakamura Y, Ichikawa E, Furumura M, Otsuka F. Exp Dermatol., 2013 Apr;22(4):262-265. doi: 10.1111/exd.12115. Epub 2013 Mar 26.
13. Modulation of Matrix Metalloprotease-2 Levels by Mechanical Loading of Three-Dimensional Mesenchymal Stem Cell Constructs: Impact on In Vitro Tube Formation. Glaeser. , Geissler S, Ode A, Schipp CJ, Matziolis G, Taylor WR, Knaus P, Perka C, Duda GN, Kasper G. Tissue Eng Part A. 2010 Oct;16(10):3139-48.
14. A Novel Function of p38-Regulated/Activated Kinase in Endothelial Cell Migration and Tumor Angiogenesis. Yoshizuka N, Chen RM, Xu Z, Liao R, Hong L, Hu WY, Yu G, Han J, Chen L, Sun P. Mol. Cell. Biol., 2012 Feb;32:606-618.
15. miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo. Shin KK, Lee AL, Kim JY, Lee SY, Bae YC, Jung JS. Biochem Biophys Res Commun., 2012 Jun;422(4):633-8.
Inhibition of ERK1/2 Worsens Intestinal Ischemia/Reperfusion Injury. Ban K, Peng Z, Kozar RA. PLoS One. 8(9): e76790.
16. Supplemental Oxygen Reverses Hypoxia Induced Smooth Muscle Cell Proliferation by Modulating HIF-alpha and VEGF Levels in a Rabbit Arteriovenous Fistula Model. Wan J, Lata C, Santilli A, Green D, Roy S, Santilli S. Ann Vasc Surg. 2013 Dec 14. pii: S0890-5096(13)00667-5.
17. GRK2 blockade with betaARKct is essential for cardiac beta2-adrenergic receptor signaling towards increased contractility. Salazar NC, Vallejos X, Siryk A, Rengo G, Cannavo A, Liccardo D, De Lucia C, Gao E, Leosco D, Koch WJ, Lymperopoulos A. Cell Commun Signal. 2013 Aug;11(1):64. [Epub ahead of print].
18. Protective Role of p70S6K in Intestinal Ischemia/Reperfusion Injury in Mice. Ban K, Kozar RA. PLoS One., 2012;7(7):e41584. 013 Sep;8(9):e76790.
19. Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung, Crouzier D, Follot S, Gentilhomme E, Flahaut E, Arnaud R, Dabouis V, Castellarin C, Debouzy JC. Toxicology. 2010 Jun 4;272(1-3):39-45.
20. Adora2b signaling on bone marrow derived cells dampens myocardial ischemia-reperfusion injury. Koeppen M, Harter PN, Bonney S, Bonney M, Reithel S, Zachskorn C, Mittelbronn M, Eckle T. Anesthesiology. 2012 Jun;116(6):1245-57.
Rat Cytokine ELISA Strips
1. Poor Wheel-Running Exercise Can Decrease Blood Pressure through Hormonal Control and Increase Endurance Exercise Capacity in Middle-Aged Normal Rats. S Sakata, T Hanaoka, R Ishizawa, K Iwami, Y Takada. Journal of Biosciences and Medicines, 2015, 3, 10-24.
2. Effect of Fructooligosaccharides Fraction from Psacalium decompositum on Inflammation and Dyslipidemia in Rats with Fructose-Induced Obesity. Merino-Aguilar H, Arrieta-Baez D, Jiménez-Estrada M, Magos-Guerrero G, Hernández-Bautista RJ, Susunaga-Notario AC, Almanza-Pérez JC, Blancas-Flores G, Román-Ramos R, Alarcón-Aguilar FJ. Nutrients 2014 ;6, 591-604.
3. Heme Oxygenase (HO-1) Rescue of Adipocyte Dysfunction in HO-2 Deficient Mice via Recruitment of Epoxyeicosatrienoic Acids (EETs) and Adiponectin. Burgess AP, Vanella L, Bellner L, Gotlinger K, Falck JR, Abraham NG, Schwartzman ML, Kappas A. Cell Physiol Biochem. 2012;29(1-2):99-110.
4. Lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in BioBreeding rats. Valladares R, Bojilova L, Potts AH, Cameron E, Gardner C, Lorca G, Gonzalez CF. FASEB J. 2013 Apr;27(4):1711-20.
5. Pharmacologic suppression of inflammation by a dipheyldifluoroketone, EF24, in a rat model of fixed-volume hemorrhage improves survival. Yadav VR, Sahoo K, Roberts PR, Awasthi V. J Pharmacol Exp Ther. 2013 Aug.[Epub ahead of print].
6. Macrophage Adiponectin Expression Improves Insulin Sensitivity and Protects Against Inflammation and Atherosclerosis, Luo N, Liu J, Chung BH, Yang Q, Klein RL, Garvey WT, Fu Y. Diabetes. 2010 Apr;59(4):791-9.
7. Chemopreventive efficacy of hesperetin (citrus flavonone) against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Toxicol Mech Methods. 2012 Jun;22(5):397-408.
8. Mechanisms underlying the varied mammary carcinogenicity of theenvironmental pollutant 6-nitrochrysene and its metabolites (-)-[R,R]- and (+)-[S,S] -1,2-dihydroxy-1,2-dihydro-6-nitrochrysene in the rat. Sun YW, Guttenplan JB, Cooper T, Krzeminski J, Aliaga C, Boyiri T, Kosinska W, Zhao ZL, Chen KM, Berg A, Amin SG, El-Bayoumy K. Chem Res Toxicol. 2013 Mar 5. [Epub ahead of print]
9. Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring. Forrest CM, Khalil OS, Pisar M, Smith RA, Darlington LG, Stone TW. Mol Brain., 2012 Jun;5(1):22.
10. Pharmacologic suppression of inflammation by a dipheyldifluoroketone, EF24, in a rat model of fixed-volume hemorrhage improves survival. Yadav VR, Sahoo K, Roberts PR, Awasthi V. J Pharmacol Exp Ther. 2013 Aug.[Epub ahead of print].
11. Acute inflammatory responses of nanoparticles in an intra-tracheal instillation rat model.AL Armstead, VC Minarchick, DW Porter… - PloS one, 2015. Published: March 4, 2015 DOI: 10.1371/journal.pone.0118778.
12. Improvement by the Phytotherapeutic Agent Eviprostat of Detrusor Overactivity, Downregulation of Pharmacological Receptors and Urinary Cytokines in Rats with Cyclophosphamide-Induced Cystitis. Nasrin S, Masuda, E, Kugaya H, Ito Y, Yamada S. J Urol. 2013 Mar;189(3):1123-9. doi: 10.1016/j.juro.2012.09.054. Epub 2012 Sep 20.
13. Effects of Saw Palmetto Extract on Urodynamic Parameters, Bladder Muscarinic and Purinergic Receptors and Urinary Cytokines in Rats with Cyclophosphamide. Nasrin S, Masuda E, Kugaya H, Ito Y, Yamada S. J Urol. 2013 Mar;189(3):1123-9.
14. Massage Improves Growth Quality by Decreasing Body FatDeposition in Male Preterm Infants. Moyer-Mileur LJ, Haley S, Slater H, Beachy J, Smith SL. J Pediatr. 2012 Oct 11.
15. Chemopreventive efficacy of hesperetin (citrus flavonone) against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Nalini N, Aranganathan S, Kabalimurthy J. Toxicol Mech Methods.,2012 Jun;22(5):397-408.
16. Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. Yen-Cheng Chen, Ching-Chun Ho, Chih-Hsun Yi, Xiu-Zhu Liu, Tzu-Ting Cheng, Chen-Fuh Lam. Plos One, vol. 12, no. 11, Feb. 2017, doi:10.1371/journal.pone.0187434.
17. Effects of Curcumin Nanoparticles in Isoproterenol-Induced Myocardial Infarction. Boarescu, Paul-Mihai, et al. Oxidative Medicine and Cellular Longevity, vol. 2019, 2019, pp. 1–13., doi:10.1155/2019/7847142.
18. Effects of Exogenous Neuroglobin (Ngb) on Retinal Inflammatory Chemokines and Microglia in a Rat Model of Transient Hypoxia. Tun, Sai Bo Bo, Veluchamy Amutha Barathi, Chi D. Luu, Myoe Naing Lynn, and Anita S. Y. Chan. Scientific Reports 9.1 (2019):
19. Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition. Xingjuan Fan, Kenneth Elkin, Yunwei Shi, Zhihong Zhang, Yaqin Cheng, Jingxiao Gu, Jiale Liang, Caiping Wang & Xunming Ji. Neurological Research, 2020, DOI: 10.1080/01616412.2020.1782079.
20. Singular and short-term anesthesia exposure in the developing brain induces persistent neuronal changes consistent with chronic neurodegenerative disease. Hogarth, K., Vanama, R.B., Stratmann, G. et al. Sci Rep 11, 5673 (2021). https://doi.org/10.1038/s41598-021-85125-5
21. Persistent Abnormal Immunocytes Induced Systemic Bone Loss in Locally Irradiated Rats. Hong, W., Tang, L., Ge, R. et al. Calcif Tissue Int (2021). https://doi.org/10.1007/s00223-021-00883-8
Human Cytokine ELISA Kits
1. Monocyte chemoattractant protein-1, transforming growth factor-β1, nerve growth factor, resistin and hyaluronic acid as serum markers: comparison between recurrent acute and chronic pancreatitis.M Ganesh Kamath, C Ganesh Pai, Asha Kamath and Annamma Kurien , Hepatobiliary & Pancreatic Hepatobiliary Pancreat Dis Int，Vol 00，No 0.
2. 2,4,5-TMBA, a Bitter Principle in Plants, Suppresses Adipogenesis through the Regulation of ERK1. YW Wang, CF Kuo - Journal of Agricultural and Food Chemistry, 2014.
3. Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo. Dai Y, Chen S, Shah R, Pei XY, Wang L, Almenara JA, Kramer LB, Dent P, Grant S. Blood. 2011 Feb 10;117(6):1947-57. doi: 10.1182/blood-2010-06-291146. Epub 2010 Dec 10.
4. Postoperative simple biochemical markers for prediction of bone metastases in Egyptian breast cancer patients. Morcos NY, Zakhary NI, Said MM, Tadros MM. Ecancermedicalscience. , 2013 Apr-15;7:305. doi: 10.3332/ecancer.2013.305. Print 2013.
5. Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis. Uzhachenko R, Issaeva N, Boyd K, Ivanov SV, Carbone. J Pathol. 2012 Aug;227(4):456-69.DP, Ivanova AV.
6. Restraint stress alters neutrophil and macrophage phenotypes during wound healing. Tymen SD, Rojas IG, Zhou X, Fang ZJ, Zhao Y, Marucha PT. Brain Behav Immun. 2013 Feb;28:207-17. doi: 10.1016/j.bbi.2012.07.013. Epub 2012 Aug 3.
7. Oxidized LDL-induced angiogenesis involves sphingosine-1-phosphate. Prevention by anti-S1P antibody. C Camaré, M Trayssac, B Garmy‐Susini, E Mucher. British Journal of Pharmacology 2014.Volume 172, Issue 1, pages 106–118, January 2015.
8. Mitogenic Activity of Sulfated Chitosan and Cellulose Derivatives is Related to Protection of FGF-2 from Proteolytic Cleavage. Weltrowski A, da Silva Almeida ML, Peschel D, Zhang K, Fischer S, Groth T. Macromol Biosci. 2012 Jun;12(6):740-50.
9. CCL18 in a Multiplex Urine-Based Assay for the Detection of Bladder Cancer. Urquidi V, Kim J, Chang M, Dai Y, Rosser CJ, Goodison S. PLoS One. 2012;7(5):e37797.
10. The Effect of e-learning on the Promotion of Optoelectronics Technology and Daily Livings Literacy among Students in Universities of Technology. Chen CP, Tai DW, Chen WJ, Lai HM. World Academyof Science, Engineering and Technology., 2012; 65:439-443.
11. Suppression of Transcription Factor Early Growth Response 1 Reduces Herpes Simplex Virus Type I-induced Corneal Disease in Mice. Yao HW, Chen SH, Li C, Tung YY, Chen SH. J Virol. 2012 Aug;86(16):8559-67. doi: 10.1128/JVI.00505-12. Epub 2012 May 30.
12. Synergism of plant-derived polyphenols in adipogenesis: Perspectives and implications. Herranz-López M, Fernández-Arroyo S, Pérez-Sanchez A, Barrajón-Catalán E, Beltrán-Debón R, Menéndez JA, Alonso-Villaverde C, Segura-Carretero A, Joven J,Micol V. Phytomedicine. 2012 Feb 15;19(3-4):253-61. doi: 10.1016/j.phymed.2011.12.001. Epub 2012 Jan 24.
13. Adipokines (adiponectin and plasminogen activator inhhibitor-1) in metabolic syndrome. Garg MK, Dutta MK, Mahalle N. Indian J Endocrinol Metab. 2012 Jan;16(1):116-23.
14. Field-effect amperometric immuno-detection of protein biomarker. Wang J, Yau ST. Biosens Bioelectron. 2011 Nov 15;29(1):210-4.
15. Multiplex Protein Signature for the Detection of Bladder Cancer in Voided Urine Samples. Rosser CJ, Ross S, Chang M, Dai Y, Mengual L, Zhang G, Kim J, Urquidi V, Alcaraz A, Goodison S. J Urol. 2013 Jun pii: S0022-5347(13)04581-3. [Epub ahead of print].
16. Human periodontal ligament fibroblasts stimulate osteoclastogenesis in response to compression force through TNF-α-mediated activation of CD4+ T cells. Kook SH, Jang YS, Lee JC. J Cell Biochem. 2011 Oct;112(10):2891-901.
17. Reduced plasma adiponectin levels relative to oxidized low density lipoprotein and nitric oxide in coronary artery disease patients. Basati G, Pourfarzam M, Movahedian A, Samsamshariat SZ, Sarrafzadegan N. Clinics (Sao Paulo). 2011;66(7):1129-35.
18. A Multi-Analyte Assay for the Non-Invasive Detection of Bladder Cancer. Goodison S, Chang M, Dai Y, Urquidi V, Rosser CJ. PLoS One., 2012;7(10):e47469. doi: 10.1371/journal.pone.0047469. Epub 2012 Oct 19.
19. Multiplex Protein Signature for the Detection of Bladder Cancer in Voided Urine Samples. Rosser CJ, Ross S, Chang M, Dai Y, Mengual L, Zhang G, Kim J, Urquidi V, Alcaraz A, Goodison S. J Urol. 2013 Jun pii: S0022-5347(13)04581-3. [Epub ahead of print].
20. Duplexed On-Microbead Binding Assay for Competitive Inhibitor of Epidermal Growth Factor Receptor by Quantitative Flow Cytometry. Lan WJ, Hao GK, Wang J, Zhang RH, Lan W, Wang RM, Sun R, Wang TF. Basic Clin Pharmacol Toxicol. 2010 Jul;107(1):560-4.
21. Altered Intramuscular Lipid Metabolism Relates to Diminished Insulin Action in Men, but Not Women, in Progression to Diabetes. Perreault L, Bergman BC, Hunerdosse DM, Eckel RH. Obesity (Silver Spring). 2010 Nov;18(11):2093-100.
22. Decreased plasma cytokines associate with low platelet counts in aplastic anemia and immune thrombocytopenic purpura. Feng X, Scheinberg P, Samsel L, Rios O, Chen J, McCoy JP Jr, Ghanima W, Bussel JB, Young NS. J Thromb Haemost. 2012 Aug;10(8):1616-23.
23. Label-Free Quantitation of a Cancer Biomarker in Complex Media Using Silicon Photonic Microring Resonators. Washburn AL, Gunn LC, Bailey RC. Anal Chem. 2009 Nov 15;81(22):9499-506.
24. Cancer biomarkers detection using 3D microstructured protein chip: Implementation of customized multiplex immunoassay. Yanga Z, Chevolota Y, Ataman-Önalb Y, Choquet-Kastylevskyb G, Souteyranda E, Laurenceaua E. Sens Actuators B Chem., 2012 Dec;175:22-28.
Mouse Cytokine ELISA Kits
1. VEGF optimizes the formation of tissue-engineered small intestine. Jamil A Matthews1, Frédéric G Sala1, Allison L Speer1, David Warburton1 & Tracy C Grikscheit. Regen Med. 2011 Sep;6(5):559-67.
2. Mesenchymal-Specific Inhibition of Vascular Endothelial Growth Factor (VEGF) Attenuates Growth in Neonatal Mice. Matthews JA, Sala FG, Speer AL, Li Y, Warburton D, Grikscheit TC. J Surg Res. 2012 Jan;172(1):40-7. Epub 2011 May 17. doi: 10.1016/j.jss.2011.04.043. Epub 2011 May 17.
3. Decreased plasma cytokines associate with low platelet counts in aplastic anemia and immune thrombocytopenic purpura. Feng X, Scheinberg P, Samsel L, Rios O, Chen J, McCoy JP Jr, Ghanima W, Bussel JB, Young NS. J Thromb Haemost. 2012 Aug;10(8):1616-23.
Rat Cytokine ELISA Kits
1. Effect of Liposomal Curcumin on Acetaminophen Hepatotoxicity by Down-Regulation of Oxidative Stress and Matrix Metalloproteinases. Dogaru, Gabriela, et al. In Vivo, vol. 34, no. 2, 2020, pp. 569–582., doi:10.21873/invivo.11809.
2. Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses. Schuchman EH, Ge Y, Lai A, Borisov Y, Faillace M, Eliyahu E, He X, Iatridis J, Vlassara H, Striker G, Simonaro CM. PLoS One. 2013;8(1):e54459. doi: 10.1371/journal.pone.0054459. Epub 2013 Jan 24.
3. Early TBI-Induced Cytokine Alterations are Similarly Detected by Two Distinct Methods of Multiplex Assay. Mukherjee S, Katki K, Arisi GM, Foresti ML, Shapiro LA. Front Mol Neurosci. 2011;4:21. doi: 10.3389/fnmol.2011.00021. Epub 2011 Sep
miRNA Research
miRNA Northern Blot Assays
1. Identification and Characterization of High Temperature Stress Responsive Novel MiRNAs in French Bean (Phaseolus Vulgaris). Jyothi, M. N., D. V. Rai, and R. Nagesh Babu. Appl Biochem Biotechnol Applied Biochemistry and Biotechnology 176.3 (2015): 835-49.
2. Global Identification of Ginkgo Biloba MicroRNAs and Insight into Their Role in Metabolism Regulatory Network of Terpene Trilactones by High-throughput Sequencing and Degradome Analysis. Ye, Jiabao, Xian Zhang, Junping Tan, Feng Xu, Shuiyuan Cheng, Zexiong Chen, Weiwei Zhang, and Yongling Liao. Industrial Crops and Products 148 (2020): 112289.
3. NFI-A disrupts myeloid cell differentiation and maturation in septic mice.C McClure, E Ali, D Youssef, ZQ Yao, CE McCall. Journal of Leukocyte Biology.Published online before print August 10, 2015, doi: 10.1189/jlb.4A0415-171RR. jlb.4A0415-171RR
4. MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells Alessandro Salvi, Cristiano Sabelli, Silvia Moncini, Marco Venturin, Bruna Arici, Paola Riva, Nazario Portolani, Stefano M. Giulini, Giuseppina De Petro, Sergio Barlati First published: 16 April 2009 DOI: 10.1111/j.1742-4658.2009.07014.x
5. A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism. Yang Xu, Munaf Zalzala, Jiesi Xu, Yuanyuan Li, Liya Yin & Yanqiao Zhang , Nature Communications 6,Article number:7466 doi:10.1038/ncomms8466 Published 23 June 2015
6. Stress Induces p38 MAPK-Mediated Phosphorylation and Inhibition of Drosha-Dependent Cell Survival. Q Yang, W Li, H She, J Dou, DM Duong, Y Du… - Molecular Cell, 2015
7. Identification and comparative analysis of differentially expressed miRNAs in leaves of two wheat (Triticum aestivum L.) genotypes during dehydration stress.X Ma, Z Xin, Z Wang, Q Yang, S Guo, X Guo, L Cao… - BMC Plant Biology, 2015
8. MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1. S Rajendiran, AV Parwani, RJ Hare, S Dasgupta… - Molecular Cancer, 2014
9. The miR-134 attenuates the expression of transcription factor FOXM1 during pluripotent NT2/D1 embryonal carcinoma cell differentiation. Y Chen, L Meng, Q Yu, D Dong, G Tan, X Huang, Y Tan - Experimental Cell Research, 2014
10. Gingerolinduced myeloid leukemia cell death is initiated by reactive oxygen species and activation of miR-27b expression. Rastogi N, Gara RK, Trivedi R, Singh A, Dixit P, Maurya R, Duggal S, Bhatt ML, Singh S, Mishra DP. Free Radic Biol Med. 2014 Mar;68:288-301.
11. Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse. Thai TH, Patterson HC, Pham DH, Kis-Toth K, Kaminski DA, Tsokos GC. Proc Natl Acad Sci U S A. 2013 41983;110(50):20194-9.
12. Selective Depletion of CD4+CD25+Foxp3+ Regulatory T Cells by Low-Dose Cyclophosphamide Is Explained by Reduced Intracellular ATP Levels. Zhao J, Cao Y, Lei Z, Yang Z, Zhang B, Huang B. Cancer Res. 2010 Jun 15;70(12):4850-8.
13. Impaired Micro-RNA Pathways Diminish Osteoclast Differentiation and Function. Sugatani T, Hruska KA. J Biol Chem. 2009 Feb 13;284(7):4667-78.
14. miRNA let-7e Modulates the Wnt Pathway and Early Nephrogenic Markers in Mouse Embryonic Stem Cell Differentiation. Viñas JL, Ventayol M, Brüne B, Jung M, Sola A, Pi F, Mastora C, Hotter G.. PLoS One. 2013 Apr-10;8(4): e60937
15. Expression of miRNAs regulates Growth and Development of French bean (Phaseolus vulgaris) under Salt and Drought Stress conditions. Nageshbabu R, Jyothi MN, Sharadamma N, Sahu Sarika, Rai DV, Devaraj VR. Int. Res. J. Biological Sci. 2013 Jan;2(1): 52-56.
16. Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct. Zhang T, Cheng T, Wei L, Cai Y, Yeo AE, Han J, Yuan YA, Zhang J, Xia N. Virol J. 2012 Jun 18;9:118.
17. OxLDL causes both epigenetic modification and signaling regulation on the microRNA-29b gene: Novel mechanisms for cardiovascular diseases. Chen KC, Liao YC, Hsieh IC, Wang YS, Hu CY, Juo SH. J Mol Cell Cardiol. 2012 Mar;52(3):587-95.
18. Glucocorticoid regulation of a novel HPV–E6–p53–miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. Shi M, Du L, Liu D, Qian L, Hu M, Yu M, Yang Z, Zhao M, Chen C, Guo L, Wang L, Song L, Ma Y, Guo N. J Pathol. 2012 Oct;228(2):148-57. doi: 10.1002/path.3997. Epub 2012 Apr 18.
19. Expression of Micro-RNA-145 is regulated by a highly conserved genomic sequence 3′ to the pre-miR . La Rocca G, Shi B, Sepp-Lorenzino L, Baserga R. J Cell Physiol. 2011 Mar;226(3):602-7.
20. Functional analysis of microRNAs in human hepatocellular cancer stem cells. Meng F, Glaser SS, Francis H, DeMorrow S, Han Y, Passarini JD, Stokes A, Cleary JP, Liu X, Venter J, Kumar P, Priester S, Hubble L, Staloch D, Sharma J, Liu CG, Alpini G. J Cell Mol Med. 2012 Jan;16(1):160-73.
21. Negative feedback regulation between microRNA let-7g and the oxLDL receptor LOX-1. Chen KC, Hsieh IC, Hsi E, Wang YS, Dai CY, Chou WW, Juo SH. J Cell Sci. 2011 Dec 1;124(Pt 23):4115-24.
22. Characterization of the stress associated microRNAs in Glycine max by deep sequencing. Li H, Dong Y, Yin H, Wang N, Yang J, Liu X, Wang Y, Wu J, Li X. BMC Plant Biol. 2011 Nov 23;11:170
23. Latency-associated nuclear antigen inhibits lytic replication of Kaposi's sarcoma-associated herpesvirus by regulating let-7a/RBPJ signaling. Qi, Yan, et al. Virology, 2019, doi:10.1016/j.virol.2019.02.019.
24. Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics. Blumental-Perry, A., Jobava, R., Bederman, I. et al. Commun Biol 3, 626 (2020). https://doi.org/10.1038/s42003-020-01322-4
miRNA Luciferase Reporter Vectors
1. Activated mineralocorticoid receptor regulates micro-RNA-29b in vascular smooth muscle cells. M Bretschneider, B Busch, D Mueller, A Nolze. The FASEB Journal, 2016. Published online before print January 4, 2016, doi: 10.1096/fj.15-271254 fj.15-271254.
2. MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.Sanjeev K Srivastava, Arun Bhardwaj, Sumit Arora, Nikhil Tyagi, Seema Singh, Joel Andrews, Steve McClellan, Bin Wang and Ajay P Singh.British Journal of Cancer 113, 660-668 (11 August 2015) | doi:10.1038/bjc.2015.252.
3. Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells.I Hennemeier, HU Humpf, M Gekle, G Schwerdt - Toxicology. 2014 Oct 3;324:116-22. doi: 10.1016/j.tox.2014.07.012. Epub 2014 Aug 1.
4. MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanl Exposure in fetal neural sem cells .PC Tsai, S Bake, S Balaraman, J Rawlings. Bio Biology Open . July 25, 2014 doi: 10.1242/bio.20147765.
5. Reducible Micelleplexes are Stable Systems for Anti-miRNA Delivery in Cerebrospinal Fluid. Zhang, Y., Buhrman, J. S., Liu, Y., Rayahin, J. E., & Gemeinhart, R. A. (2016). Mol. Pharmaceutics. doi:10.1021/acs.molpharmaceut. 5b00933.
6. Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2. J H Kim, S G Park, S-Y Song, J K Kim, and J-H Sung. Cell Death Dis. 2013 April; 4(4): e588.
7. Hypoxia Induced Aggressiveness of Prostate Cancer Cells Is Linked with Deregulated Expression of VEGF, IL-6 and miRNAs That Are Attenuated by CDF. Bao B, Ahmad A, Kong D, PLoS ONE, 2012; 7(8):e43726. doi: 10.1371/journal.pone.0043726. Epub 2012 Aug 27.Ali S, Azmi AS, Li Y, Banerjee S, Padhye S, Sarkar FH.
8. HIV-1 Tat Protein Promotes Neuronal Dysfunction through Disruption of MicroRNAs. Chang JR, Mukerjee R, Bagashev A, Del Valle L, Chabrashvili T, Hawkins BJ, He JJ, Sawaya BE. J Biol Chem. 2011 Nov 25;286(47):41125-34.
9. Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi). Pan Q, Ramakrishnaiah V, Henry S, Fouraschen S, de Ruiter PE, Kwekkeboom J, Tilanus . Gut. 2012 Sep;61(9):1330-9.HW, Janssen HL, van der Laan LJ.
10. .Decrease of miR-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid. Yang YM, Seo SY, Kim TH, Kim SG. Hepatology. 2012 Dec ;56(6):2209-20. doi: 10.1002/hep.25912.
11. MicroRNA-21 Expression is regulated by β-catenin/STAT3 Pathway and Promotes Glioma Cell Invasion by Direct Targeting RECK.Han L, Yue X, Zhou X, Lan FM, You G, Zhang W, Zhang KL, Zhang CZ, Cheng JQ, Yu. CNS Neurosci Ther. 2012 Jul;18(7):573-583.SZ, Pu PY, Jiang T, Kang CS.
12. Decreased miR-29 Suppresses Myogenesis in CKD. Wang XH, Hu Z, Klein JD, Zhang L, Fang F, Mitch WE. J Am Soc Nephrol. 2011 Nov;22(11):2068-76.
13. The induction of epigenetic regulation of PROS1 gene in lung fibroblasts by gold nanoparticles and implications for potential lung injury.Ng CT, Dheen ST, Yip WC, Ong CN, Bay BH, Lanry Yung LY. Biomaterials. 2011 Oct;32(30):7609-15.
14. Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. Sureban SM, May R, Mondalek FG, Qu D, Ponnurangam S, Pantazis P, Anant S, Ramanujam RP, Houchen CW. J Nanobiotechnology. 2011 Sep 19;9:40.
15. Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. Clément S, Peyrou M, Sanchez-Pareja A, Bourgoin L, Ramadori P, Suter D, Vinciguerra M, Guilloux K, Pascarella S, Rubbia-Brandt L, Negro F, Foti M. Hepatology. 2011 Jul;54(1):38-49.
16. Control of oligodendroglial cell number by the miR-17-92 cluster. Budde H, Schmitt S, Fitzner D, Opitz L, Salinas-Riester G, Simons M.Development. 2010 Jul;137(13):2127-32.
17. MicroRNA-155 contributes to preeclampsia by down-regulating CYR61 .Zhang Y, Diao Z, Su L, Sun H, Li R, Cui H, Hu Y.Am J Obstet Gynecol. 2010 May;202(5):466.e1-7.
18. Selective Blockade of DCAMKL-1 Results in Tumor Growth Arrest by a Let-7a MicroRNA-Dependent Mechanism . Sureban SM, May R, Ramalingam S, Subramaniam D, Natarajan G, Anant S, Houchen CW. Gastroenterology, August 2009, 137: 649–659.e2.
19. The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by de-repressing the v-ets erythroblastosis virus E26 oncogene homolog 1 -matrix metalloproteinase-1 pathway.Chan YC, Roy S, Huang Y, Khanna S, Sen CK. J Biol Chem. 2012 Nov 30;287(49):41032-43. doi: 10.1074/jbc.M112.413294. Epub 2012 Oct 11.
20. Dicer Knockdown Inhibits Endothelial Cell Tumor Growth via MicroRNA 21a-3p Targeting of Nox-4. Gordillo GM, Biswas A, Khanna S, Pan X, Sinha M, Roy S, Sen CK. J Biol Chem. 2014 Feb 4. [Epub ahead of print].
21. Functional MicroRNA Is Transferred between Glioma Cells.Katakowski M, Buller B, Wang X, Rogers T, Chopp M. Cancer Res. 2010 Nov 1;70(21):8259-63.
22. Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth. Xin H, Li Y, Buller B, Katakowski M, Zhang Y, Wang X, Shang X, Zhang. Stem Cells. 2012 Jul;30(7):1556-64. ZG, Chopp M.
23. miR-9 and miR-200 Regulate PDGFRβ-Mediated Endothelial Differentiation of Tumor Cells in Triple-Negative Breast Cancer.Elvira D'Ippolito, Ilaria Plantamura, Lucia Bongiovanni, Patrizia Casalini, Sara Baroni, Claudia Piovan, Rosaria Orlandi, Ambra V. Gualeni, Annunziata Gloghini, Anna Rossini, Sara Cresta, Anna Tessari, Filippo De Braud, Gianpiero Di Leva, Claudio Tripodo and Marilena V. Cancer Res. 2016 Sep 15;76(18):5562-72. doi: 10.1158/0008-5472.CAN-16-0140. Epub 2016 Jul 11.
24. Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth.Hongqi Xin,a Yi Li,a Ben Buller,a Mark Katakowski,a Yi zhang,a Xinli Wang,a Xia Shang,a Zheng Gang Zhang,a and Michael Choppa,b. Stem Cells. 2012 Jul; 30(7): 1556–1564. doi: 10.1002/stem.1129.
25. miR-200b Targets Ets-1 and Is Down-regulated by Hypoxia to Induce Angiogenic Response of Endothelial Cells.Chan YC, Khanna S, Roy S, Sen CK. J Biol Chem. 2011 Jan 21;286(3):2047-56.
26. Steroidogenic genes expressions are repressed by high levels of leptin and the JAK/STAT signaling pathway in MA-10 Leydig cells. David A. Landry, François Sormany, Josée Haché, Pauline Roumaud, Luc J. Martin. Molecular and Cellular Biochemistry 2017 March 25. doi:10.1007/s11010-017-3017-x.
27. Dicer reprograms stromal fibroblasts to a pro-inflammatory and tumor-promoting phenotype in ovarian cancer. Yang, Zongyuan, et al. Cancer Letters, 2017, doi:10.1016/j.canlet.2017.11.026.
miRNA Arrays
1. MicroRNA-21 is Induced by Rapamycin in a Model of Tuberous Sclerosis (TSC) and Lymphangioleiomyomatosis(LAM). Trindade AJ, Medvetz DA, Neuman NA, Myachina F, Yu J, Priolo C, Henske EP. PLoS One. 2013;8(3):e60014.
2. Prevention of Chlamydia-induced infertility by inhibition of local caspaseactivity.Igietseme JU, Omosun Y, Partin J, Goldstein J, He Q, Joseph K, Ellerson D, Ansari U, Eko FO, Bandea C,Zhong G, Black CM. J Infect Dis. 2013 Apr; 207(7):1095-104. doi: 10.1093/infdis/jit009. Epub 2013 Jan 9.
3. Induction of MiR-17-3p and MiR-160a by TNFα and LPS. Jiang X, Li N. Cell Biochem Funct. 2011 Mar;29(2):164-70.
4. Downregulation of Inflammatory MicroRNAs by Ig-like Transcript 3 Is Essential for the Differentiation of Human CD8+ T Suppressor Cells. Chang CC, Zhang QY, Liu Z, Clynes RA, Suciu-Foca N, Vlad G. J Immunol., 2012 Apr;188(7):3042-52.
5. Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT.Ghosh AK, Nagpal V, Covington JW, Michaels MA, Vaughan DE. Cell Signal. 2012 May;24(5):1031-6.
6. Microrna Expression Is Dysregulated In Lymphangioleiomyomatosis (LAM). Trindade AJ, Myachina F, Medvetz D, Neuman N, Henske EP. Am. J. Respir. Crit. Care Med., 2011 May; 183: A3660.
7. MicroRNA27a Regulates Cardiomyocytic Apoptosis During Cardioplegia-Induced Cardiac Arrest by TargetingInterleukin 10-Related Pathways. Yeh CH, Chen TP, Wang YC, Lin YM, Fang SW. Shock. 2012 Dec;38(6):607-14.
8. MTORC1-Dependent Dysregulated Expression Of MicroRNA Contributes To The Pathogenesis Of Lymphangioleiomyomatosis (LAM) Trindade AJ, Medvetz DA, Neuman NA, Myachina F, Zhang E, Yu J, Henske EP. Am. J. Respir. Crit. Care Med., 2012 May; 185: A6821.
9. Curcumin inhibits the proliferation and invasion of human osteosarcoma cell line MG-63 by regulating miR-138, D Yu, F An, X He, X Cao. International Journal of Clinical and Experimental 2015. Int J Clin Exp Pathol. 2015; 8(11): 14946–14952. Published online 2015 Nov 1.
10. Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT. Ghosh AK, Nagpal V, Covington JW, Michaels MA, Vaughan DE. Cell Signal. 2012 May;24(5):1031-6.
11. ST Depression, Arrhythmia, Vagal Dominance, and Reduced Cardiac Micro-RNA in Particulate-Exposed Rats. Farraj AK, Hazari MS, Haykal-Coates N, Lamb C, Winsett DW, Ge Y, Ledbetter AD, Carll AP, Bruno M, Ghio A, Costa DL. Am J Respir Cell Mol Biol. 2011 Feb;44(2):185-96.
12. Differential profiling of human red blood cells during storage for 52 selected microRNAs.Meganathan Kannan, Chintamani Atreya.Kannan M, Atreya C. Transfusion. 2010 Jul;50(7):1581-8.
13. Circulating Blood MicroRNAs In The Diagnosis Of Lung Cancer.Le W, Wang W, Ghani M, Upadhyay D.Am. J. Respir. Crit. Care Med., May 2010; 181: A3482.
14. Membrane array–based differential profiling of platelets during storage for 52 miRNAs associated with apoptosis.Kannan M, Mohan KV, Kulkarni S, Atreya C.Transfusion. 2009 Jul;49(7):1443-50
14. Homoharringtonine Inhibits Allergic Inflammations by Regulating NF-κB-miR-183-5p-BTG1 Axis. Kim, Misun, Hyein Jo, Yoojung Kwon, Youngmi Kim, Hyun Suk Jung, and Dooil Jeoung. Frontiers in Pharmacology 11 (2020): 1032. doi: 10.3389/fphar.2020.01032
Direct Hybridization Plate Assays
1. The role of miR-210, E2F3 and ephrin A3 in angiosarcoma cell proliferation. Satoko Nakashima,Masatoshi Jinnin,Hisashi Kanemaru,Ikko Kajihara,Toshikatsu Igata,Sayo Okamoto,Yukino Tazaki,Shinichi Masuguchi,Satoshi Fukushima,Mamiko Masuzawa,Yasuyuki Amoh,Mikio Masuzawa,Hironobu Ihn, European Journal of Dermatology. 2017 Jul 25, DOI: 10.1684/ejd.2017.3084
2. Mitochondrial Oxidative Stress-Induced Epigenetic Modifications in Pancreatic Epithelial Cells. Mishra PK, Raghuram GV, Jain D, Jain SK, Khare NK, Pathak N. Int J Toxicol. 2014 Feb 24.
3. Ankyrin repeat and Single KH domain 1 (ANKHD1) drives renal cancer cell proliferation via binding to and altering a subset of miRNAs. Fragiadaki, Maria, and Martin P. Zeidler. Journal of Biological Chemistry, 2018, doi:10.1074/jbc.ra117.000975.
Gene Expression Analysis
Single Cell Gene Expression Analysis
1. Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility. Abou-Saleh H, Pathan AR, Daalis A, Hubrack S, Abou-Jassoum H, Al-Naeimi H, Rusch NJ, Machaca K J Biol Chem. 2013 41958;288(46):32941-51.
2. A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. Zhao X, Tang Z, Zhang H, Atianjoh FE, Zhao JY, Liang L, Wang W, Guan X, Kao SC, Tiwari V, Gao YJ, Hoffman PN, Cui H, Li M, Dong X, Tao YX. Nat Neurosci. 2013 Aug;16(8):1024-31.
3. Protein Kinase CK2 Inhibition Down Modulates the NF-κB and STAT3 Survival Pathways, Enhances the Cellular Proteotoxic Stress and Synergistically Boosts the Cytotoxic Effect of Bortezomib on Multiple Myeloma and Mantle Cell Lymphoma Cells. Manni S, Brancalion A, Mandato E, Tubi LQ, Colpo A, Pizzi M, Cappellesso R, Zaffino F, Di Maggio SA, Cabrelle A, Marino F, Zambello R, Trentin L, Adami F, Gurrieri C, Semenzato G, Piazza F. PLoS One. 2013 41544;8(9):e75280.
4. IP3 receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility. Abou-Saleh H, Pathan AR, Daalis A, Hubrack S, Abou-Jassoum H, Al-Naeimi H, Rusch NJ, Machaca K. J Biol Chem. 2013 Oct 4. [Epub ahead of print]
5. Direct Quantification of mRNA and miRNA from Cell Lysates Using Reverse Transcription Real Time PCR: A Multidimensional Analysis of the Performance of Reagents and Workflows. Ho YK, Xu WT, Too HP. PLoS One. 2013 41522;8(9):e72463.
6. Osteoprotegerin Contributes to the Metastatic Potential of Cells with a Dysfunctional TSC2 Tumor-Suppressor Gene. Steagall WK, Pacheco-Rodriguez G, Glasgow CG, Ikeda Y, Lin JP, Zheng G, Moss J. Am J Pathol. 2013 Sep;183(3):938-50.
7. Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan® Low Density Array. Demarest TG, Murugesan N, Shrestha B, Pachter JS. J Neurosci Methods., 2012 ;206(2):200-4.
8. Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression.Clowney EJ, Legros MA, Mosley CP, Clowney FG, Markenskoff-Papadimitriou EC, Myllys M, Barnea G, Larabell CA, Lomvardas S. Cell., 2012 41222;151(4):724-37.
9. Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus. Murugesan N, Paul D, Lemire Y, Shrestha B, Ge S, Pachter JS. Fluids Barriers CNS., 2012 41125;9(1):15.
10. Alterations in Tight Junction Protein and IgG Permeability Accompany Leukocyte Extravasation Across the Choroid Plexus During Neuroinflammation.Shrestha, Bandana BS; Paul, Debayon MS; Pachter, Joel S. PhD . Journal of neuropathology and experimental …, 2014
11. Chronological in Vivo Imaging Reveals Endothelial Inflammation Prior to Neutrophils Accumulation and Lipid Deposition in HCD-Fed Zebrafish. Atherosclerosis. Luo, Hui, et al. 2019, doi:10.1016/j.atherosclerosis.2019.09.017.
12. N6‐Methyladenosine Demethylase FTO Contributes to Neuropathic Pain by Stabilizing G9a Expression in Primary Sensory Neurons. Li, Y., Guo, X., Sun, L., Xiao, J., Su, S., Du, S., Li, Z., Wu, S., Liu, W., Mo, K., Xia, S., Chang, Y.‐J., Denis, D. and Tao, Y.‐X. (2020). Adv. Sci.. doi:10.1002/advs.201902402
13. The transcription factor TAL1 and miR-17-92 create a regulatory loop in hematopoiesis. Meyer, A., Herkt, S., Kunze-Schumacher, H. et al. Sci Rep 10, 21438 (2020). https://doi.org/10.1038/s41598-020-78629-z
14. Downregulation of a Dorsal Root Ganglion-Specifically Enriched Long Noncoding RNA is Required for Neuropathic Pain by Negatively Regulating RALY-Triggered Ehmt2 Expression. Pan, Z., Du, S., Wang, K., Guo, X., Mao, Q., Feng, X., Huang, L., Wu, S., Hou, B., Chang, Y.‐J., Liu, T., Chen, T., Li, H., Bachmann, T., Bekker, A., Hu, H., Tao, Y.‐X. Adv. Sci. 2021, 2004515. https://doi.org/10.1002/advs.202004515
cDNA Plate Arrays
1. Endogenous Human CaMKII Inhibitory Protein Suppresses Tumor Growth by Inducing Cell Cycle Arrest and Apoptosis through Down-regulation of the Phosphatidylinositide 3-Kinase/Akt/HDM2 Pathway. Ma S, Yang Y, Wang C, Hui N, Gu L, Zhong H, Cai Z, Wang Q, Zhang Q, Li N, Cao X. J Biol Chem. 2009 Sep 11;284(37):24773-82.
2. Embryonic Overexpression of Receptors for Advanced Glycation End-Products by Alveolar Epithelium Induces an Imbalance between Proliferation and Apoptosis. Stogsdill JA1, Stogsdill MP, Porter JL, Hancock JM, Robinson AB, Reynolds PR. Am J Respir Cell Mol Biol Vol 47, Iss. 1, pp 60–66, Jul 2012
3. Δ-9,11 modifications of glucocorticoids dissociate NF-κB inhibitory efficacy from GRE-associated side effects. Baudy AR, Reeves E, Damsker J, Heier C, Garvin L, Dillingham BC, McCall J, Rayavarapu S, Wang Z, Vander Meulen J, Sali A, Jahnke V, Duguez S, Dubois D,Rose M, Nagaraju K, Hoffman E. J Pharmacol Exp Ther. 2012 Jul 3.
4. Stem cells from foreign body granulation tissue accelerate recovery from acute kidney injury. Patel J, Pancholi N, Gudehithlu KP, Sethupathi P, Hart PD, Dunea G, Arruda JA, Singh AK. Nephrol Dial Transplant. 2012 May;27(5):1780-6.
5. A novel vascular EET synthase: role of CYP2C7 Sun D, Jiang H, Wu H, Yang Y, Kaley G, Huang A. Am J Physiol Regul Integr Comp Physiol. 2011 Dec;301(6):R1723-30.
6. siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells. Edited by Judit Ovádi. Qin XY, Wei F, Yoshinaga J, Yonemoto J, Tanokura M, Sone H. FEBS Lett. 2011 Oct 20;585(20):3310-5.
7. Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Isaacs JT, Antony L, Dalrymple S, Brennen WN, Gerber S, Hammers H, Wissing MD, Kachhap SK, Luo J, Xing L,Bjork P, Olsson A, Björk A, Leanderson T. Cancer Res. 2012 Nov 13.
8. HIF-stabilizing bioactive glasses for directing MSC behaviour . MM Azevedo, O Tsigkou, R Nair, G Jell, J Jones… - Tissue Engineering, 2014
9.Nitration of the Tumor Suppressor Protein p53 at Tyrosine 327 Promotes p53 Oligomerization and Activation. Yakovlev VA, Bayden AS, Graves PR, Kellogg GE, Mikkelsen RB. Biochemistry., 2010 Jun 29;49(25):5331-9. doi: 10.1021/bi100564w.
10. Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype intrastuzumab resistant HER2-overexpressing breast cancer cells. Vadgama JV, Wu Y, Ginther C, Kim J, Mosher N, Chung S, Slamon D. Mol Cancer Res. 2012 Oct 15.
11. A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells. Yanyuan Wu, Trinh Tran, Sami Dwabe, Marianna Sarkissyan, Juri Kim, Miguel Nava, Sheilah Clayton, Richard Pietras, Robin Farias-Eisner, Jaydutt V. Vadgama. Breast Cancer Research and Treatment. 2017 March 23. doi: 10.1007/s10549-017-4211-y
12. Conditionally induced RAGE expression by proximal airway epithelial cells in transgenic mice causes lung inflammation.B Garrett Bodine, Brock G Bennion, Emma Leatham, Felix R Jimenez, Alex J Wright, Zac R Jergensen,Connor J Erickson, Cameron M Jones, Jeff P Johnson, Steven M Knapp and Paul R Reynolds . Respiratory Research, 2014 (Published online)
13. Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis. D Qu, N Weygant, R May, P Chandrakesan. Plos One Published: August 18, 2015, DOI: 10.1371/journal.pone.0134212
14. Expression and Potential Role of Cellular Retinol Binding Protein I in Psoriasis. Costanza, Gaetana, Elena Doldo, Amedeo Ferlosio, Chiara Tarquini, Daniela Passeri, Raffaella Cascella, Mauro Bavetta, Alessandro Di Stefani, Claudio Bonifati, Sara Agostinelli, Federica Centofanti, Emiliano Giardina, Elena Campione, Luca Bianchi, Pietro Donati, Aldo Morrone, and Augusto Orlandi. " Oncotarget 9.95 (2018)
Biomarkers and Key Proteins
Autoimmune ELISA Kits
1. STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus. C Ding, X Chen, P Dascani, X Hu, R Bolli, H Zhang, The Journal of Immunology, 2016. Published online before print April 25, 2016, doi: 10.4049/jimmunol.1502043.
2. Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces. Azzam, Kathleen M., et al. JCI Insight, vol. 2, no. 16, 2017, doi:10.1172/jci.insight.91914.
3. Dental pulp-derived stem cell-conditioned media attenuates secondary Sjögren's syndrome via suppression of inflammatory cytokines in the submandibular glands. Ogata, K., Matsumura-Kawashima, M., Moriyama, M., Kawado, T., & Nakamura, S. Regenerative Therapy, Volume 16, 2021, Pages 73-80, ISSN 2352-3204, https://doi.org/10.1016/j.reth.2021.01.006.
4. Invariant natural killer T cells in lupus patients promote IgG and IgG autoantibody production. L Shen, H Zhang, M Caimol, CJ Benike, European journal of Immunology, 2014.
5. Metabolic Requirements of Human pro-Inflammatory B Cells in Aging and Obesity. Frasca, Daniela, et al. Plos One, vol. 14, no. 7, 2019, doi:10.1371/journal.pone.0219545.
Others
Signosis Luciferase Substrate
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TET1 Overexpression Mitigates Neuropathic Pain Through Rescuing the Expression of μ-Opioid Receptor and Kv1.2 in the Primary Sensory Neurons. Wu, Qiang, et al. Neurotherapeutics, 2018, doi:10.1007/s13311-018-00689-x.
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Fn14 Participates in Neuropathic Pain Through NF-ΚB Pathway in Primary Sensory Neurons. Huang, Li-Na, et al. Molecular Neurobiology, 2019, doi:10.1007/s12035-019-1545-y.
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Direct Antioxidant Properties of Methotrexate: Inhibition of Malondialdehyde-Acetaldehyde-Protein Adduct Formation and Superoxide Scavenging. Matthew C. Zimmermana, Dahn L. Clemensb, c, Michael J. Duryeeb, Cleofes Sarmientoa, Andrew Chioub, Carlos D. Hunterb, Jun Tiana, Lynell W. Klassenb, c, James R. O’Dellb, c, Geoffrey M. Thieleb, c, Redox Biology,2017.07.018, doi: 10.1016/j.redox.2017.07.018