Stable Cell Line

Luciferase Reporter Stable Cell Lines

Hunter, S. A., McIntosh, B. J., Shi, Y., et al. (2021). An engineered ligand trap inhibits leukemia inhibitory factor as pancreatic cancer treatment strategy. Communications Biology, 4, 452. https://doi.org/10.1038/s42003-021-01928-2
Lundqvist, J., Persson, K. M., & Oskarsson, A. (2021). Glass-bottled drinking water: A time capsule to study the historic presence of hazardous chemicals using effect-based methods. Environmental Sciences Europe, 33, 34. https://doi.org/10.1186/s12302-021-00476-0
Vitale, L. A., He, L. Z., Thomas, L. J., et al. (2020). Development of CDX-527: A bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy. Cancer Immunology, Immunotherapy: CII. https://doi.org/10.1007/s00262-020-02610-y
Mayoux, M., et al. (2020). Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy. Science Translational Medicine, 12(534). https://doi.org/10.1126/scitranslmed.aav7431
Paraiso, I. L., Revel, J. S., Choi, J., Miranda, C. L., Lak, P., Kioussi, C., Bobe, G., Gombart, A. F., Raber, J., Maier, C. S., & Stevens, J. F. (2020). Targeting the liver-brain axis with hop-derived flavonoids improves lipid metabolism and cognitive performance in mice. Molecular Nutrition & Food Research. https://doi.org/10.1002/mnfr.202000341
Darowski, D., et al. (2019). P329G-CAR-J: A novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation. Protein Engineering, Design & Selection. https://doi.org/10.1093/protein/gzz027
Lundqvist, J., et al. (2019). Innovative drinking water treatment techniques reduce the disinfection-induced oxidative stress and genotoxic activity. Water Research, 155, 182–192. https://doi.org/10.1016/j.watres.2019.02.052
Koseki, T., et al. (2019). Discovery of a new STAT3 inhibitor acting on the linker domain. Biological and Pharmaceutical Bulletin, 42(5), 792–800. https://doi.org/10.1248/bpb.b18-00992
Sambon, M., et al. (2019). Thiamine and benfotiamine protect neuroblastoma cells against paraquat and β-amyloid toxicity by a coenzyme-independent mechanism. Heliyon, 5(5). https://doi.org/10.1016/j.heliyon.2019.e01710
Watts, C. L. (2018). Occurrence and in vitro toxicity of unregulated disinfection by-products in two Saskatchewan drinking water treatment plants. Handle Proxy, Universidade Da Coruña. https://hdl.handle.net/10388/11499
Bhanja, P., Norris, A., Gupta-Saraf, P., Hoover, A., & Saha, S. (2018). BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury. Stem Cell Research & Therapy, 9(1). https://doi.org/10.1186/s13287-017-0763-3
Eskla, K.-L., et al. (2018). Hypothermia augments stress response in mammalian cells. Free Radical Biology and Medicine. https://doi.org/10.1016/j.freeradbiomed.2018.04.571
Yun, Y. S., et al. (2018). A new ent-norabietant diterpenoid from roots of Euphorbia lathyris L. Tetrahedron Letters. https://doi.org/10.1016/j.tetlet.2018.06.017
Banerjee, P., et al. (2018). Diversification of Bw4 specificity and recognition of a nonclassical MHC class I molecule implicated in maternal–fetal tolerance by killer cell Ig-like receptors of the rhesus macaque. The Journal of Immunology. https://doi.org/10.4049/jimmunol.1800494
Thangirala, S., Bharali, D. J., Yalcin, M., Darwish, N. H. E., Coskun, M. D., Keating, K. A., Lin, H.-Y., Davis, P. J., & Mousa, S. A. (2017). Targeted delivery of cisplatin to tumor xenografts via the nanoparticle component of nano-diamino-tetrac. Nanomedicine, 12(3), 195-205. https://doi.org/10.2217/nnm-2016-0315
Persad, A., Venkateswaran, G., Hao, L., Garcia, M. E., Yoon, J., Sidhu, J., & Persad, S. (2017). Active β-catenin is regulated by the PTEN/PI3 kinase pathway: A role for protein phosphatase PP2A. Genes & Cancer, 8(11-12), 368–382. https://doi.org/10.18632/genesandcancer.128
Tao, Q., Wu, C., Xu, R., Niu, L., Qin, J., Liu, N., Zhang, P., & Wang, C. (2017). Diallyl trisulfide inhibits proliferation, invasion, and angiogenesis of glioma cells by inactivating Wnt/β-catenin signaling. Cell and Tissue Research. https://doi.org/10.1007/s00441-017-2678-9
Zimmerman, M. C., Clemens, D. L., Duryee, M. J., Sarmiento, C., Chiou, A., Hunter, C. D., Tian, J., Klassen, L. W., O’Dell, J. R., & Thiele, G. M. (2017). Direct antioxidant properties of methotrexate: Inhibition of malondialdehyde-acetaldehyde-protein adduct formation and superoxide scavenging. Redox Biology. https://doi.org/10.1016/j.redox.2017.07.018
Persad, A., Venkateswaran, G., Hao, L., Garcia, M. E., Yoon, J., Sidhu, J., & Persad, S. (2016). Active β-catenin is regulated by the PTEN/PI3 kinase pathway: A role for protein phosphatase PP2A. Genes & Cancer, 7(11-12), 368–382. https://doi.org/10.18632/genesandcancer.128
Palliyaguru, D. L., Chartoumpekis, D. V., & Wakabayashi, N. (2016). Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms. Free Radical Biology and Medicine. https://doi.org/10.1016/j.freeradbiomed.2016.10.003
Muralidharan-Chari, V., Kim, J., Abuawad, A., & Naeem, M. (2016). Thymoquinone modulates blood coagulation in vitro via its effects on inflammatory and coagulation pathways. International Journal of Molecular Sciences, 17(4), 474. https://doi.org/10.3390/ijms17040474
Zhao, M., Howard, E. W., Parris, A. B., Guo, Z., Zhao, Q., & Yang, X. (2016). Alcohol promotes migration and invasion of triple-negative breast cancer cells through activation of p38 MAPK and JNK. Molecular Carcinogenesis. https://doi.org/10.1002/mc.22538
Zheng, N., Song, Z., Liu, Y., Zhang, R., Zhang, R., & Yao, C. (2015). Redox-responsive, reversibly-crosslinked thiolated cationic helical polypeptides for efficient siRNA encapsulation and delivery. Journal of Controlled Release, 205, 231–239. https://doi.org/10.1016/j.jconrel.2015.05.009
Vazquez-Ortiz, G., Chisholm, C., Xu, X., Lahusen, T. J., & Li, C. (2014). Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer-associated gene-1. Breast Cancer Research, 16(3), R67. https://doi.org/10.1186/bcr3682

NFAT Jurkat Stable Cell Lines

Ullah, I., Symmes, K., Keita, K., Zhu, L., Grunst, M. W., Li, W., Mothes, W., Kumar, P., & Uchil, P. D. (2024). Beta spike-presenting SARS-CoV-2 virus-like particle vaccine confers broad protection against other VOCs in mice. Preprints. https://doi.org/10.20944/preprints202406.0899.v1
Boucher, J. C., Li, G., Kotani, H., Cabral, M. L., Morrissey, D., Lee, S. B., Spitler, K., Beatty, N. J., Cervantes, E. V., Shrestha, B., Yu, B., Kazi, A., Wang, X., Sebti, S. M., & Davila, M. L. (2021). CD28 costimulatory domain-targeted mutations enhance chimeric antigen receptor T-cell function. Cancer Immunology Research, 9(1), 62-74. https://doi.org/10.1158/2326-6066.CIR-20-0253
Grunst, M. W., Grandea, A. G. III, Janaka, S. K., Hammad, I., Grimes, P., Karl, J. A., Wiseman, R., O'Connor, D. H., & Evans, D. T. (2020). Functional interactions of common allotypes of rhesus macaque FcγR2A and FcγR3A with human and macaque IgG subclasses. The Journal of Immunology, 205(12), 3319-3332. https://doi.org/10.4049/jimmunol.2000501
Oh, S. A., Wu, D. C., Cheung, J., Navarro, A., Xiong, H., Cubas, R., Totpal, K., Chiu, H., Wu, Y., Comps-Agrar, L., Leader, A. M., Merad, M., Roose-Germa, M., Warming, S., Yan, M., Kim, J. M., Rutz, S., & Mellman, I. (2020). PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer. Nature Cancer, 1(7), 681-691. https://doi.org/10.1038/s43018-020-0075-x
Darowski, D., Jost, C., Stubenrauch, K., Wessels, U., Benz, J., Ehler, A., Freimoser-Grundschober, A., Brünker, P., Mössner, E., Umaña, P., Kobold, S., & Klein, C. (2019). P329G-CAR-J: A novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation. Protein Engineering, Design & Selection, 32(5), 207-218. https://doi.org/10.1093/protein/gzz027
Choi, B. D., Yu, X., Castano, A. P., Bouffard, A. A., Schmidts, A., Larson, R. C., Bailey, S. R., Boroughs, A. C., Frigault, M. J., Leick, M. B., Scarfò, I., Cetrulo, C. L., Demehri, S., Nahed, B. V., Cahill, D. P., Wakimoto, H., Curry, W. T., Carter, B. S., & Maus, M. V. (2019). CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity. Nature Biotechnology, 37(9), 1049-1058. https://doi.org/10.1038/s41587-019-0192-1
Banerjee, P., Ries, M., Janaka, S. K., Grandea, A. G. III, Wiseman, R., O'Connor, D. H., Golos, T. G., & Evans, D. T. (2018). Diversification of Bw4 specificity and recognition of a nonclassical MHC class I molecule implicated in maternal-fetal tolerance by killer cell Ig-like receptors of the rhesus macaque. The Journal of Immunology, 201(9), 2776-2786. https://doi.org/10.4049/jimmunol.1800494

Transcription Factor Assays

TF Activation Profiling Plate Arrays

Combo TF Activation (FA-1106)

Schmidt, K., Buquicchio, F., Carroll, J. S., Distel, R. J., & Novina, C. D. (2017). Rata: A method for high-throughput identification of RNA bound transcription factors. Journal of Biological Methods, 4(1). https://doi.org/10.14440/jbm.2017.171

TF Activation Profiling Plate I (FA-1001)

Lin, Z., Lv, D., Liao, X., Peng, R., Liu, H., Wu, T., Wu, K., Sun, Y., & Zhang, Z. (2023). CIRCUBXN7 promotes macrophage infiltration and renal fibrosis associated with the IGF2BP2-dependent SP1 mrna stability in diabetic kidney disease. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1226962
Sen-Kilic, E., Huckaby, A. B., Damron, F. H., & Barbier, M. (2022). P. aeruginosa type III and type VI secretion systems modulate early response gene expression in type II pneumocytes in vitro. BMC Genomics, 23(1). https://doi.org/10.1186/s12864-022-08554-0
Thümmler, K., Williams, M. T., Kitson, S., Sood, S., Akbar, M., Cole, J. J., Hunter, E., Soutar, R., & Goodyear, C. S. (2022). Targeting 3D chromosomal architecture at the rank loci to suppress myeloma-driven osteoclastogenesis. OncoImmunology, 11(1). https://doi.org/10.1080/2162402x.2022.2104070
Tsai, Y.-T., Li, Y., Ryu, J., Su, P.-Y., Cheng, C.-H., Wu, W.-H., Li, Y.-S., Quinn, P. M. J., Leong, K. W., & Tsang, S. H. (2021). Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration. The American Journal of Human Genetics, 108(5), 903–918. https://doi.org/10.1016/j.ajhg.2021.04.006
Bhattacharya, B., Xiao, S., Chatterjee, S., Urbanowski, M., Ordonez, A., Ihms, E. A., Agrahari, G., Lun, S., Berland, R., Pichugin, A., Gao, Y., Connor, J., Ivanov, A. R., Yan, B.-S., Kobzik, L., Koo, B.-B., Jain, S., Bishai, W., & Kramnik, I. (2021). The integrated stress response mediates necrosis in murine mycobacterium tuberculosis granulomas. Journal of Clinical Investigation, 131(3). https://doi.org/10.1172/jci130319
Zhong, R., Miao, R., Meng, J., Wu, R., Zhang, Y., & Zhu, D. (2021). Acetoacetate promotes muscle cell proliferation via the mir-133b/SRF axis through the MEK-erk-MEF2 pathway. Acta Biochimica et Biophysica Sinica, 53(8), 1009–1016. https://doi.org/10.1093/abbs/gmab079
Bogucka, K., Pompaiah, M., Marini, F., Binder, H., Harms, G., Kaulich, M., Klein, M., Michel, C., Radsak, M. P., Rosigkeit, S., Grimminger, P., Schild, H., & Rajalingam, K. (2020). Erk3/MAPK6 controls IL-8 production and chemotaxis. eLife, 9. https://doi.org/10.7554/elife.52511
Euteneuer, A. M., Seeger‐Nukpezah, T., Nolte, H., & Henjakovic, M. (2019). Estrogen receptor α (ERΑ) indirectly induces transcription of human renal organic anion transporter 1 (OAT1). Physiological Reports, 7(21). https://doi.org/10.14814/phy2.14229
Sampaio, N. G., Eriksson, E. M., & Schofield, L. (2018). Plasmodium falciparum PFEMP1 modulates monocyte/macrophage transcription factor activation and cytokine and chemokine responses. Infection and Immunity, 86(1). https://doi.org/10.1128/iai.00447-17
Jeong, A. L., Ka, H. I., Han, S., Lee, S., Lee, E., Soh, S. J., Joo, H. J., Sumiyasuren, B., Park, J. Y., Lim, J., Park, J. H., Lee, M. S., & Yang, Y. (2018). Oncoprotein cip 2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism. EMBO Reports, 19(5). https://doi.org/10.15252/embr.201745144
Nickkholgh, B., Sittadjody, S., Rothberg, M. B., Fang, X., Li, K., Chou, J. W., Hawkins, G. A., & Balaji, K. C. (2017). Beta-catenin represses protein kinase D1 gene expression by non-canonical pathway through Myc/max transcription complex in prostate cancer. Oncotarget, 8(45), 78811–78824. https://doi.org/10.18632/oncotarget.20229
Bhattacharya, B., Chattrerjee, S., Berland, R., Pichugin, A., Gao, Y., Connor, J., Ivanov, A., Yan, B.-S., Kobzik, L., & Kramnik, I. (2017). Macrophage Resilience and Control of Intracellular Bacteria Requires Sst1-Dependent Integration of c-Myc, Stress Response and Type I IFN Pathways. https://doi.org/10.1101/238873
Betancur, P. A., Abraham, B. J., Yiu, Y. Y., Willingham, S. B., et al. (2017). A CD47-associated super-enhancer links pro-inflammatory signaling to CD47 upregulation in breast cancer. Nature Communications, 8, Article 14802. https://doi.org/10.1038/ncomms14802
Schmidt, K., Buquicchio, F., Carroll, J. S., Distel, R. J., & Novina, C. D. (2017). Rata: A method for high-throughput identification of RNA bound transcription factors. Journal of Biological Methods, 4(1). https://doi.org/10.14440/jbm.2017.171
Chen, J.-Y., Lai, Y.-S., Tsai, H.-J., Kuo, C.-C., Yen, B. L., Yeh, S.-P., Sun, H. S., & Hung, W.-C. (2016). The oncometabolite R-2-hydroxyglutarate activates NF-ΚB-dependent tumor-promoting stromal niche for acute myeloid leukemia cells. Scientific Reports, 6(1). https://doi.org/10.1038/srep32428
Schmidt, K., Joyce, C. E., Buquicchio, F., Brown, A., Ritz, J., Distel, R. J., Yoon, C. H., & Novina, C. D. (2016). The lncrna SLNCR1 mediates melanoma invasion through a conserved sra1-like region. Cell Reports, 15(9), 2025–2037. https://doi.org/10.1016/j.celrep.2016.04.018
von Elsner, L., Hagemann, S., Just, I., & Rohrbeck, A. (2016). C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors. Naunyn-Schmiedeberg’s Archives of Pharmacology, 389(9), 1021–1031. https://doi.org/10.1007/s00210-016-1270-2
Hudson, C. A., McArdle, C. A., & López Bernal, A. (2016). Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium. Molecular Human Reproduction, 22(7), 512–525. https://doi.org/10.1093/molehr/gaw031
Liu, Y., Tian, X., Li, Y., Liu, D., Liu, M., Zhang, X., Zhang, Q., Yan, C., & Han, Y. (2016). Up-regulation of CREG expression by the transcription factor GATA1 inhibits high glucose- and high palmitate-induced apoptosis in human umbilical vein endothelial cells. PLOS ONE, 11(5). https://doi.org/10.1371/journal.pone.0154861
Philip, M., Chiu, E. Y., Hajjar, A. M., & Abkowitz, J. L. (2016). TLR stimulation dynamically regulates heme and iron export gene expression in macrophages. Journal of Immunology Research, 2016, 1–10. https://doi.org/10.1155/2016/4039038
Fulciniti, M., Amodio, N., Bandi, R. L., Munshi, M., Yang, G., Xu, L., Hunter, Z., Tassone, P., Anderson, K. C., Treon, S. P., & Munshi, N. C. (2014). Myd88-independent growth and survival effects of SP1 transactivation in Waldenström Macroglobulinemia. Blood, 123(17), 2673–2681. https://doi.org/10.1182/blood-2014-01-550509
Tam, A., Wadsworth, S., Dorscheid, D., Man, S.-F. P., & Sin, D. D. (2014). Estradiol increases mucus synthesis in bronchial epithelial cells. PLoS ONE, 9(6). https://doi.org/10.1371/journal.pone.0100633
Toubal, A., Clément, K., Fan, R., Ancel, P., Pelloux, V., Rouault, C., Veyrie, N., Hartemann, A., Treuter, E., & Venteclef, N. (2013, January 2). SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation. Journal of Clinical Investigation, 123(1), 362-379.
Derer, S., Berger, S., Schlaeth, M., Schneider-Merck, T., Klausz, K., Lohse, S., Overdijk, M. B., Dechant, M., Kellner, C., Nagelmeier, I., Scheel, A. H., Lammerts van Bueren, J. J., van de Winkel, J. G. J., Parren, P. W. H. I., Peipp, M., & Valerius, T. (2012). Oncogenic kras impairs EGFR antibodies’ efficiency by C/ebpβ-dependent suppression of EGFR expression. Neoplasia, 14(3). https://doi.org/10.1593/neo.111636
Cui, C., Shi, Q., Zhang, X., Liu, X., Bai, Y., Li, J., Liu, S., Hu, S., & Wei, Y. (2012, March). CRP promotes MMP-10 expression via c-Raf/MEK/ERK and JAK1/ERK pathways in cardiomyocytes. Cell Signaling, 24(3), 810-818.
Peluso, J. J., Lodde, V., & Liu, X. (2012, August). Progesterone regulation of progesterone receptor membrane component 1 (PGRMC1) sumoylation and transcriptional activity in spontaneously immortalized granulosa cells. Endocrinology, 153(8), 3929-3939.
Yao-Borengasser, A., Yu, X., Dhakal, I. B., Edavana, V. K., Williams, S., & Kadlubar, S. A. (2012, April). Identification of human nuclear factor 1 (NF-1) as a potential transcription factor which regulates the gene expression of sulfotransferase isoform 1A1 (SULT1A1) in human breast cancer. Cancer Research, 72, 1296.

TF Activation Profiling Plate II (FA-1002)

Yang, R., Wang, X., Liu, H., Chen, J., Tan, C., Chen, H., & Wang, X. (2024). EGR-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli. Cell Communication and Signaling, 22(1). https://doi.org/10.1186/s12964-024-01488-y

Duan, Y., Zhang, S., Xing, Y., Wu, Y., Zhao, W., Xie, P., Zhang, H., Gao, X., Qin, Y., Wang, Y., Ma, X., Du, Y., & Liu, H. (2023). Adiponectin-mediated promotion of CD44 suppresses diabetic vascular inflammatory effects. iScience, 26(4), 106428. https://doi.org/10.1016/j.isci.2023.106428

Kang, B. W., Kim, F., Cho, J.-Y., Kim, S., Rhee, J., & Choung, J. J. (2022). Phosphodiesterase 5 inhibitor mirodenafil ameliorates Alzheimer-like pathology and symptoms by multimodal actions. Alzheimer’s Research & Therapy, 14(1). https://doi.org/10.1186/s13195-022-01034-3
Lee, Y., Kim, S., Fang, X., Song, N., Kim, D., Suh, J., Na, H., Kim, K., Baek, J., & Surh, Y. (2022). JNK-mediated Ser27 phosphorylation and stabilization of SIRT1 promote growth and progression of colon cancer through deacetylation-dependent activation of Snail. Molecular Oncology, 16(7), 1555–1571. https://doi.org/10.1002/1878-0261.13143
Zhou, X., Li, L., Guo, X., Zhang, C., Du, Y., Li, T., Tong, K., Zhu, C., & Wang, Z. (2022). HBXIP induces anoikis resistance by forming a reciprocal feedback loop with NRF2 to maintain redox homeostasis and stabilize PRDX1 in breast cancer. NPJ Breast Cancer, 8(1). https://doi.org/10.1038/s41523-021-00374-x

Pan, C., Kang, J., Hwang, J. S., Li, J., Boese, A. C., Wang, X., Yang, L., Boggon, T. J., Chen, G. Z., Saba, N. F., Shin, D. M., Magliocca, K. R., Jin, L., & Kang, S. (2021). Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24845-8
Yan, Y., Zhang, Y., Li, M., Zhang, Y., Zhang, X., Zhang, X., Xu, Y., Wei, W., Wang, J., Xu, X., Song, Q., & Zhao, C. (2021). C644‐0303, a small‐molecule inhibitor of the WNT/β‐catenin pathway, suppresses colorectal cancer growth. Cancer Science, 112(11), 4722–4735. https://doi.org/10.1111/cas.15118
Kay, M. (2021). Stress-induced transcription factors and their role in RNA disruption in ovarian cancer cells. Laurentian University of Sudbury. https://zone.biblio.laurentian.ca/handle/10219/3774
Zabala, V., Boylan, J. M., Thevenot, P., Frank, A., Senthoor, D., Iyengar, V., Kim, H., Cohen, A., Gruppuso, P. A., & Sanders, J. A. (2019). Transcriptional changes during hepatic ischemia-reperfusion in the rat. PLOS ONE, 14(12). https://doi.org/10.1371/journal.pone.0227038
Morales-Martinez, M., Valencia-Hipolito, A., Vega, G. G., Neri, N., Nambo, M. J., Alvarado, I., Cuadra, I., Duran-Padilla, M. A., Martinez-Maza, O., Huerta-Yepez, S., & Vega, M. I. (2019). Regulation of Krüppel-like factor 4 (KLF4) expression through the transcription factor Yin-Yang 1 (YY1) in non-Hodgkin B-cell lymphoma. Oncotarget, 10(22), 2173–2188. https://doi.org/10.18632/oncotarget.26745

Wang, D., Yu, W., Lian, J., Wu, Q., Liu, S., Yang, L., Li, F., Huang, L., Chen, X., Zhang, Z., Li, A., Liu, J., Sun, Z., Wang, J., Yuan, W., & Zhang, Y. (2020). Th17 cells inhibit CD8+ T cell migration by systematically downregulating CXCR3 expression via IL-17A/STAT3 in advanced-stage colorectal cancer patients. Journal of Hematology & Oncology, 13(1). https://doi.org/10.1186/s13045-020-00897-z
Yao, J., Zhao, X., Tan, F., Cao, X., Guo, S., Li, X., Huang, Z., Diabakte, K., Wang, L., Liu, M., Shen, Z., Li, B., Cao, Z., Sheng, S., Lu, M., Cao, Y., Jin, H., Zhang, Z., & Tian, Y. (2020). Early modulation of macrophage ROS-PPARγ-NF-κB signaling by SONODYNAMIC therapy attenuates neointimal hyperplasia in rabbits. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-68543-9

Meng, Y., Wang, L., Xu, J., & Zhang, Q. (2018). AP4 positively regulates LAPTM4B to promote hepatocellular carcinoma growth and metastasis, while reducing chemotherapy sensitivity. Molecular Oncology, 12(3), 373–390. https://doi.org/10.1002/1878-0261.12171
Subramani, R., Camacho, F. A., Levin, C. I., Flores, K., Clift, A., Galvez, A., Terres, M., Rivera, S., Kolli, S. N., Dodderer, J., Miranda, M., Rodriguez, A., Pedroza, D. A., Chatterjee, A., & Lakshmanaswamy, R. (2018). Foxc1 plays a crucial role in the growth of pancreatic cancer. Oncogenesis, 7(7). https://doi.org/10.1038/s41389-018-0061-7
Wang, Q., He, Z., Huang, M., Liu, T., Wang, Y., Xu, H., Duan, H., Ma, P., Zhang, L., Zamvil, S. S., Hidalgo, J., Zhang, Z., O’Rourke, D. M., Dahmane, N., Brem, S., Mou, Y., Gong, Y., & Fan, Y. (2018). Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α. Nature Communications, 9(1). https://doi.org/10.1038/s41467-018-03050-0
Jin, L., Chun, J., Pan, C., Kumar, A., Zhang, G., Ha, Y., Li, D., Alesi, G. N., Kang, Y., Zhou, L., Yu, W.-M., Magliocca, K. R., Khuri, F. R., Qu, C.-K., Metallo, C., Owonikoko, T. K., & Kang, S. (2018). The PLAG1-GDH1 axis promotes anoikis resistance and tumor metastasis through CAMKK2-AMPK signaling in LKB1-deficient lung cancer. Molecular Cell, 69(1). https://doi.org/10.1016/j.molcel.2017.11.025
Ma, Y., Wei, X., & Wu, Z. (2017). HNF‑4Α promotes multidrug resistance of gastric cancer cells through the modulation of cell apoptosis. Oncology Letters. https://doi.org/10.3892/ol.2017.7095

Kelkar, M. G., Senthilkumar, K., Jadhav, S., Gupta, S., Ahn, B.-C., & De, A. (2016). Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation. Scientific Reports, 6(1). https://doi.org/10.1038/srep19341
Tsukumo, Y., Alain, T., Fonseca, B. D., Nadon, R., & Sonenberg, N. (2016). Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3. Nature Communications, 7(1). https://doi.org/10.1038/ncomms11776
Boopalan, T., Arumugam, A., Parada, J., Saltzstein, E., & Lakshmanaswamy, R. (2015). Receptor activator for nuclear factor‐κB ligand signaling promotes progesterone‐mediated estrogen‐induced mammary carcinogenesis. Cancer Science, 106(1), 25–33. https://doi.org/10.1111/cas.12571
Kawahara, T., Shareef, H. K., Aljarah, A. K., Ide, H., Li, Y., Kashiwagi, E., Netto, G. J., Zheng, Y., & Miyamoto, H. (2015). Elk1 is up-regulated by androgen in bladder cancer cells and promotes tumor progression. Oncotarget, 6(30), 29860–29876. https://doi.org/10.18632/oncotarget.5007
Rosebeck, S., Kandarpa, M., Alonge, M. M., Jasielec, J., Dytfeld, D., Maxwell, S. P., Kraftson, S. J., McCauley, D., Shacham, S., Kauffman, M., & Jakubowiak, A. J. (2013). Effects of inhibition of XPO1/CRM1-dependent nuclear export by Selinexor (KPT-330), alone and in combination with carfilzomib (CFZ), on apoptosis and autophagy in multiple myeloma (MM). Blood, 122(21), 279–279. https://doi.org/10.1182/blood.v122.21.279.279
Messier, E. M., Bahmed, K., Tuder, R. M., Chu, H. W., Bowler, R. P., & Kosmider, B. (2013). Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke. Cell Death & Disease, 4(4). https://doi.org/10.1038/cddis.2013.96
Rosebeck, S., Kandarpa, M., Alonge, M. M., Jasielec, J., Dytfeld, D., Maxwell, S. P., Kraftson, S. J., McCauley, D., Shacham, S., Kauffman, M., & Jakubowiak, A. J. (2013, November). Effects of inhibition of XPO1/CRM1-dependent nuclear export by Selinexor (KPT 330), alone and in combination with Carfilzomib (CFZ), on apoptosis and autophagy in multiple myeloma (MM). Blood, 122(21), 279.
Le, W., Ghani, M., Gutsche, M., Wang, W., Hwang, P. H., Upadhyay, D. (2011, May). Differential regulation of microRNAs in asthmatic airways. American Journal of Respiratory and Critical Care Medicine, 183, A2067.

TF Activation Profiling Plate III (FA-1101)

Wu, Y.-L., Lin, H., Li, H.-F., Don, M.-J., King, P.-C., & Chen, H.-H. (2022). Salvia miltiorrhiza extract and individual synthesized component derivatives induce activating-transcription-factor-3-mediated anti-obesity effects and attenuate obesity-induced metabolic disorder by suppressing C/EBPΑ in high-fat-induced obese mice. Cells, 11(6), 1022. https://doi.org/10.3390/cells11061022

Stem Cell (FA-1003)

Minciacchi, V. R., Spinelli, C., Reis-Sobreiro, M., Cavallini, L., You, S., Zandian, M., Li, X., Mishra, R., Chiarugi, P., Adam, R. M., Posadas, E. M., Viglietto, G., Freeman, M. R., Cocucci, E., Bhowmick, N. A., & Di Vizio, D. (2017). Myc mediates large oncosome-induced fibroblast reprogramming in prostate cancer. Cancer Research, 77(9), 2306–2317. https://doi.org/10.1158/0008-5472.can-16-2942

Cancer Stem Cell (FA-1004)

Chaudhary, P., Yadav, K., Lee, H. J., Kang, K. W., Mo, J., & Kim, J.-A. (2024). Sirna treatment targeting integrin Α11 overexpressed via EZH2-driven axis inhibits drug-resistant breast cancer progression. Breast Cancer Research, 26(1). https://doi.org/10.1186/s13058-024-01827-4
Dahal, S., Chaudhary, P., Jung, Y.-S., & Kim, J.-A. (2023). Megakaryocyte-derived IL-8 acts as a paracrine factor for prostate cancer aggressiveness through CXCR2 activation and antagonistic AR downregulation. Biomolecules & Therapeutics, 31(2), 210–218. https://doi.org/10.4062/biomolther.2023.005
Espinoza-Sánchez, N. A., Enciso, J., Pelayo, R., & Fuentes-Pananá, E. M. (2018). An NFΚB-dependent mechanism of tumor cell plasticity and lateral transmission of aggressive features. Oncotarget, 9(42), 26679–26700. https://doi.org/10.18632/oncotarget.25465
Nandy, S. B., Orozco, A., Lopez-Valdez, R., Roberts, R., Subramani, R., Arumugam, A., Dwivedi, A. K., Stewart, V., Prabhakar, G., Jones, S., & Lakshmanaswamy, R. (2017). Glucose insult elicits hyperactivation of cancer stem cells through Mir-424–cdc42–PRDM14 signalling axis. British Journal of Cancer, 117(11), 1665–1675. https://doi.org/10.1038/bjc.2017.335

Oxidative Stress (FA-1005)

Shrishrimal, Shashank, "Molecular Mechanisms of Manganese Porphyrin Compounds in the Prevention of Radiation-Induced Fibrosis" (2020). Theses & Dissertations. 434. https://digitalcommons.unmc.edu/etd/434
Zhao, Y., Carroll, D. W., You, Y., Chaiswing, L., Wen, R., Batinic-Haberle, I., Bondada, S., Liang, Y., & St. Clair, D. K. (2017). A novel redox regulator, mntnbuoe-2-pyp5+, enhances normal hematopoietic stem/progenitor cell function. Redox Biology, 12, 129–138. https://doi.org/10.1016/j.redox.2017.02.005
Elia Martínez-Baeza, Emilio Rojas, Mahara Valverde, Metal mixture (As–Cd–Pb)-induced cell transformation is modulated by OLA1, Mutagenesis, Volume 31, Issue 4, July 2016, Pages 463–473, https://doi.org/10.1093/mutage/gew010

ER Stress (FA-1006)

Park, JJ., Lee, S.J., Baek, M. et al. FRMD6 determines the cell fate towards senescence: involvement of the Hippo-YAP-CCN3 axis. Cell Death Differ (2024). https://doi.org/10.1038/s41418-024-01333-2
Hogarth, K., Vanama, R.B., Stratmann, G. et al. Singular and short-term anesthesia exposure in the developing brain induces persistent neuronal changes consistent with chronic neurodegenerative disease. Sci Rep 11, 5673 (2021). https://doi.org/10.1038/s41598-021-85125-5
Kay, Melissa. “Stress-Induced Transcription Factors and Their Role in RNA Disruption in Ovarian Cancer Cells.” LU, Laurentian University of Sudbury, 20 May 2021, zone.biblio.laurentian.ca/handle/10219/3774.
Sreenath, T. L., Macalindong, S. S., Mikhalkevich, N., Sharad, S., Mohamed, A., Young, D., Borbiev, T., Xavier, C., Gupta, R., Jamal, M., Babcock, K., Tan, S.-H., Nevalainen, M. T., Dobi, A., Petrovics, G., Sesterhenn, I. A., Rosner, I. L., Bieberich, C. J., Nelson, P., … Srivastava, S. (2017). ETS related gene mediated androgen receptor aggregation and endoplasmic reticulum stress in prostate cancer development. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-01187-4
Marwarha, Gurdeep, et al. “Palmitate increases β-site AβPP-cleavage enzyme 1 activity and amyloid-β genesis by evoking endoplasmic reticulum stress and subsequent C/EBP homologous protein activation.” Journal of Alzheimer’s Disease, vol. 57, no. 3, 10 Apr. 2017, pp. 907–925, https://doi.org/10.3233/jad-161130.

Wnt/Beta-Catenin (FA-1007)

Kudryashova, T. V., Goncharov, D. A., Pena, A., Kelly, N., Vanderpool, R., Baust, J., Kobir, A., Shufesky, W., Mora, A. L., Morelli, A. E., Zhao, J., Ihida-Stansbury, K., Chang, B., DeLisser, H., Tuder, R. M., Kawut, S. M., Silljé, H. H., Shapiro, S., Zhao, Y., & Goncharova, E. A. (2016). Hippo–integrin-linked kinase cross-talk controls self-sustaining proliferation and survival in pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 194(7), 866–877. https://doi.org/10.1164/rccm.201510-2003oc

Cholesterol Metabolism (FA-1008)

Banerjee, A., & Singla, D. K. (2024). MSC exosomes attenuate sterile inflammation and necroptosis associated with TAK1-PJNK-NFKB mediated cardiomyopathy in Diabetic Apoe Ko mice. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1348043
Zhang, Z., Ursin, R., Mahapatra, S., & Gallicano, G. I. (2018). CRISPR/Cas9 ablation of individual mirnas from a MIRNA family reveals their individual efficacies for regulating cardiac differentiation. Mechanisms of Development, 150, 10–20. https://doi.org/10.1016/j.mod.2018.02.002

Mitochondria UPR (FA-1010)

Kuzuoglu-Ozturk, D., Hu, Z., Rama, M., Devericks, E., Weiss, J., Chiang, G. G., Worland, S. T., Brenner, S. E., Goodarzi, H., Gilbert, L. A., & Ruggero, D. (2021). Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Reports, 35(13), 109321. https://doi.org/10.1016/j.celrep.2021.109321
Hogarth, K., Vanama, R.B., Stratmann, G. et al. Singular and short-term anesthesia exposure in the developing brain induces persistent neuronal changes consistent with chronic neurodegenerative disease. Sci Rep 11, 5673 (2021). https://doi.org/10.1038/s41598-021-85125-5
Kay, Melissa. “Stress-Induced Transcription Factors and Their Role in RNA Disruption in Ovarian Cancer Cells.” LU, Laurentian University of Sudbury, 20 May 2021, zone.biblio.laurentian.ca/handle/10219/3774.

Cited in Research, Specific Product Unspecified

Tobacman, J. K., Bhattacharyya, S., & Feferman, L. (2021).** Abstract 2442: Chondroitin sulfatases and transcription factors GLI, TCF/Lef, and c-myc in prostate stem cells. *Cancer Research, 81(13_Supplement)*, 2442–2442.

Madhu, L. N., Kodali, M., Attaluri, S., Shuai, B., Melissari, L., Rao, X., & Shetty, A. K. (2021).** Melatonin improves brain function in a model of chronic Gulf War illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-Erk-CREB pathway in the hippocampus. *Redox Biology, 43*, 101973. https://doi.org/10.1016/j.redox.2021.101973
Sadava, D., & Kane, S. E. (2017, August 25).** The effect of brassinolide, a plant steroid hormone, on drug resistant small-cell lung carcinoma cells. *Biochemical and Biophysical Research Communications.* https://doi.org/10.1016/j.bbrc.2017.08.094
Shrestha, B., Xiang, J., Ge, S., Paul, D., Chianchiano, P., & Pachter, J. S. (2017, August 24).** Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis. *Neurobiology of Disease.* https://doi.org/10.1016/j.nbd.2017.08.010
Peng, C., Li, Z., Niu, Z., Niu, W., Xu, Z., Gao, H., Niu, W., Wang, J., He, Z., Gao, C., Lin, P., Agrez, M., Zhang, Z., & Niu, J. (2016).** Norcantharidin suppresses colon cancer cell epithelial-mesenchymal transition by inhibiting the αvβ6-ERK-Ets1 signaling pathway. *Scientific Reports, 6*, Article 20500. https://doi.org/10.1038/srep20500
Ravindra, K. C., Ho, W. E., Cheng, C., Godoy, L. C., & Wishnok, J. S. (2015, September 4).** An untargeted proteomics and systems-based mechanistic investigation of Artesunate in human bronchial epithelial cells. *Chemical Research in Toxicology.* https://doi.org/10.1021/acs.chemrestox.5b00105
Wu, R., Li, H., Li, T., Zhang, Y., & Zhu, D. (2015, May 29).** Myostatin regulates miR-431 expression via the Ras-Mek-Erk signaling pathway. *Biochemical and Biophysical Research Communications, 461(2)*, 224-229. https://doi.org/10.1016/j.bbrc.2015.03.159
Sharma, A., Diecke, S., Zhang, W. Y., Lan, F., He, C., Mordwinkin, N. M., Chua, K. F., & Wu, J. C. (2013, June).** The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. *Journal of Biological Chemistry, 288(25)*, 18439-18447.
Rahman, K. M., Jackson, P. J., James, C. H., Basu, B. P., Hartley, J. A., de la Fuente, M., Schatzlein, A., Robson, M., Pedley, R. B., Pepper, C., Fox, K. R., Howard, P. W., & Thurston, D. E. (2013, April).** GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models. *Journal of Medicinal Chemistry, 56(7)*, 2911-2935.
Shimura, M., Yamamoto, M., Fujii, G., Takahashi, M., Komiya, M., Noma, N., Tanuma, S., Yanaka, A., & Mutoh, M. (2012).** Novel compound SK-1009 suppresses interleukin-6 expression through modulation of activation of nuclear factor-kappaB pathway. *Biological and Pharmaceutical Bulletin, 35(12)*, 2186-2191. https://doi.org/10.1248/bpb.b12-00629
Bodnarchuk, T. W., Napper, S., Rapin, N., & Misra, V. (2012, September).** Mechanism for the induction of cell death in ONS. 76 medulloblastoma cells by Zhangfei/CREB-ZF. *Journal of Neuro-Oncology, 109(3)*, 485-501.

Promoter Binding TF Assays

Promoter Binding 1 (FA-2001)

Raphael, H. E., Hassan, G. F., Osorio, O. A., Cohen, L. S., Payne, M. D., Katz-Kiriakos, E., Tata, I., Hicks, J., Byers, D. E., Zhang, B., & Alexander-Brett, J. (2024). Activator protein transcription factors coordinate human IL-33 expression from noncanonical promoters in chronic airway disease. JCI Insight, 9(5). https://doi.org/10.1172/jci.insight.174786
Liu, Y., Tian, X., Li, Y., Liu, D., Liu, M., Zhang, X., & Han, Y. (2016). Up-regulation of CREG expression by the transcription factor GATA1 inhibits high glucose- and high palmitate-induced apoptosis in human umbilical vein endothelial cells. PLOS ONE, 11(5). https://doi.org/10.1371/journal.pone.0154861
Guo, X. M., Liu, X. P., Chang, G. B., Xu, L., Bi, Y. L., & Wang, H. Z. (2016). Characterization of the NLRC5 promoter in chicken: SNPs, regulatory elements and CpG islands. Animal Genetics. https://doi.org/10.1111/age.12450
Jain, P., Lavorgna, A., Sehgal, M., Gao, L., & Ginwala, R. (2015). Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing the complex between Tax and CREB. Retrovirology, 12(1), 23. https://doi.org/10.1186/s12977-015-0140-1
Xu, H., Wang, Z., Sun, Z., Ni, Y., & Zheng, L. (2017). GATA4 protects against hyperglycemia-induced endothelial dysfunction by regulating NOX4 transcription. Molecular Medicine Reports. https://doi.org/10.3892/mmr.2017.8062

Promoter Binding 2 (FA-2002)

Rathod, M., Kelkar, M., Valvi, S., Salve, G., & De, A. (2020). FOXA1 regulation turns benzamide HDACI treatment effect-specific in BC, promoting NIS gene-mediated targeted radioiodine therapy. Molecular Therapy - Oncolytics, 19, 93–104. https://doi.org/10.1016/j.omto.2020.08.015
Dhadve, A. C., Hari, K., Rekhi, B., Jolly, M. K., De, A., & Ray, P. (2020). Decoding molecular interplay between Runx1 and FOXO3A underlying the pulsatile IGF1R expression during the acquirement of chemoresistance. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1866(6), 165754. https://doi.org/10.1016/j.bbadis.2020.165754
Ren, L., Deng, B., Saloura, V., Park, J., & Nakamura, Y. (2019). Melk inhibition targets cancer stem cells through downregulation of sox2 expression in head and neck cancer cells. Oncology Reports. https://doi.org/10.3892/or.2019.6988
Pan, C.-H., Chen, C.-J., Shih, C.-M., Wang, M.-F., Wang, J.-Y., & Wu, C.-H. (2019). Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta. Aging, 11(19), 8085–8102. https://doi.org/10.18632/aging.102270
Wang, L., Meng, Y., Xu, J.-J., & Zhang, Q.-Y. (2018). The transcription factor AP4 promotes oncogenic phenotypes and cisplatin resistance by regulating laptm4b expression. Molecular Cancer Research, 16(5), 857–868. https://doi.org/10.1158/1541-7786.mcr-17-0519
Chen, W., Xu, H., Chen, X., Liu, Z., Zhang, W., & Xia, D. (2016). Functional and activity analysis of cattle UCP3 promoter with MRFs-related factors. International Journal of Molecular Sciences, 17(5), 682. https://doi.org/10.3390/ijms17050682
Afshari, P., Myles-Worsley, M., Cohen, O. S., Tiobech, J., et al. (2015). Characterization of a novel mutation in SLC1A1 associated with schizophrenia. Molecular Neuropsychiatry, 1(3).

Cited in Research, Specific Product Unspecified

Ketkar, H. (2023). Abstract P222: Effect of western diet on pathophysiology and cardiac gene expression profile in human AT1 receptor over-expressing hypertensive transgenic mice. Hypertension, 80(Suppl_1), AP222. https://doi.org/10.1161/hyp.80.suppl_1.p222
Sun, Z., Zhou, D., Xie, X., Wang, S., Wang, Z., Zhao, W., Xu, H., & Zheng, L. (2016). Cross-talk between macrophages and atrial myocytes in atrial fibrillation. Basic Research in Cardiology, 111(6). https://doi.org/10.1007/s00395-016-0584-z

TF Interaction Plate Arrays

He, T. (2021). Identification and clinical significance of two divergent regulators in thoracic malignancy: miR-18a and RUNX1T1 [Doctoral dissertation, Case Western Reserve University].

EMSA

Yabaji, S. M., Zhernovkov, V., Araveti, P. B., Lata, S., Rukhlenko, O. S., Abdullatif, S. A., ... & Kramnik, I. (2024). Myc dysregulation in activated macrophages initiates iron-mediated lipid peroxidation that fuels type I interferon and compromises TB resistance. *Myc Dysregulation in Activated Macrophages Initiates Iron-Mediated Lipid Peroxidation That Fuels Type I Interferon and Compromises TB Resistance*. https://doi.org/10.1101/2024.03.05.583602
Tsai, Y.-T., Li, Y., Ryu, J., Su, P.-Y., Cheng, C.-H., Wu, W.-H., ... & Tsang, S. H. (2021). Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration. *The American Journal of Human Genetics, 108*(5), 903–918. https://doi.org/10.1016/j.ajhg.2021.04.006
STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimer's disease animal model. Wan HL, Hong XY, Zhao ZH, et al. (2021). *Theranostics, 11*(11), 5511-5524. https://doi.org/10.7150/thno.56541
Dutta, P., Paico, K., Gomez, G., Wu, Y., & Vadgama, J. (2020). Transcriptional regulation of CCL2 by PARP1 is a driver for invasiveness in breast cancer. *Cancers, 12*(5), 1317. https://doi.org/10.3390/cancers12051317
McCormack, R., Hunte, R., Podack, E. R., Plano, G. V., & Shembade, N. (2020). An essential role for perforin-2 in type I IFN signaling. *The Journal of Immunology*. https://doi.org/10.4049/jimmunol.1901013
Chung, S. S., Dutta, P., Chard, N., Wu, Y., Chen, Q.-H., Chen, G., & Vadgama, J. (2019). A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-κB inactivation in colorectal cancer cells. *Oncotarget, 10*(44), 4516–4531. https://doi.org/10.18632/oncotarget.27000
Henry, D., Arora, R., Mannel, J., Tripathi, S., Bhattacharya, D., & Velagapudi, R. (2019). Involvement of pRb-E2F pathway in green tea extract-induced growth inhibition of human myeloid leukemia cells. *Leukemia Research*. https://doi.org/10.1016/j.leukres.2018.12.014
Li, X., Cai, X., Zhang, X., Li, Q., Feng, X., Wei, J., ... & Zhen, J. (2018). Tau accumulation activates STAT1 triggering memory deficits via suppressing NMDA receptor expression. *doi:10.1101/437814*.
Marazioti, A., Lilis, I., Vreka, M., Apostolopoulou, H., Kalogeropoulou, A., Giopanou, I., ... & Stathopoulos, G. T. (2018). Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κB addiction in malignant pleural effusion. *Nature Communications, 9*(1). https://doi.org/10.1038/s41467-018-03051-z
Punganuru, S. R., Madala, H. R., Arutla, V., & Srivenugopal, K. S. (2018). Selective killing of human breast cancer cells by the styryl lactone (R)-goniothalamin is mediated by glutathione conjugation, induction of oxidative stress, and marked reactivation of the R175H mutant p53 protein. *Carcinogenesis*. https://doi.org/10.1093/carcin/bgy093
Wu, J., Jin, Z., Yang, X., & Yan, L. J. (2018). Post-ischemic administration of 5-methoxyindole-2-carboxylic acid at the onset of reperfusion affords neuroprotection against stroke injury by preserving mitochondrial function and attenuating oxidative stress. *Biochemical and Biophysical Research Communications*. https://doi.org/10.1016/j.bbrc.2018.02.106
Zhang, L., Zhao, J., Gurkar, A., Niedernhofer, L. J., & Robbins, P. D. (2018). Methods to quantify the NF-κB pathway during senescence. *Methods in Molecular Biology, Cellular Senescence*, 231–250. https://doi.org/10.1007/978-1-4939-8931-7_18
Hou, X., Snarski, P., Higashi, Y., Yoshida, T., Jurkevich, A., Delafontaine, P., & Sukhanov, S. (2017). Nuclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I protect smooth muscle cells against oxidant-induced cell death. *The FASEB Journal*. https://doi.org/10.1096/fj.201601082R
Jiang, X., Engel, B. J., Liu, H., Inouye, C., Nunez, S., Palomares, M., & Tong, Z. (2017). Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. *Nature Communications, 8*(1). https://doi.org/10.1038/s41467-017-02290-w
BASAK, D., PUNGANURU, S. R., & SRIVENUGOPAL, K. S. (2016). Piperlongumine exerts cytotoxic effects against cancer cells with mutant p53 proteins at least in part by restoring the biological functions of the tumor suppressor. *International Journal of Oncology, 48*(4), 1426–1436. https://doi.org/10.3892/ijo.2016.3372
Wang, S., Sun, Z., Zhao, W., Wang, Z., Wu, M., Pan, Y., Yan, H., & Zhu, J. (2016). CD97/ADGRE5 inhibits LPS induced NF

TF Filter Plate Assays

Bogucka, K., Pompaiah, M., Marini, F., Binder, H., Harms, G., Kaulich, M., Klein, M., Michel, C., Radsak, M. P., Rosigkeit, S., Grimminger, P., Schild, H., & Rajalingam, K. (2020). Erk3/MAPK6 controls IL-8 production and chemotaxis. eLife, 9. https://doi.org/10.7554/elife.52511
Jia, Q.-P., Zhang, J., Liu, X., Zhang, X., Chen, M., Zhou, Z., Xu, H., Li, H., Wu, Y., & Zhao, Y. (2019). Upregulation of MTA1 expression by human papillomavirus infection promotes CDDP resistance in cervical cancer cells via modulation of NF-κB/APOBEC3B cascade. Cancer Chemotherapy and Pharmacology, 84(2), 267-278. https://doi.org/10.1007/s00280-018-03766-2
Almiron Bonnin, D. A., Havrda, M. C., Lee, M. C., Liu, H., Zhang, Z., Nguyen, L. N., Harrington, L. X., Hassanpour, S., Cheng, C., & Israel, M. A. (2017). Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia. Oncogene, 37(8), 1107–1118. https://doi.org/10.1038/onc.2017.404
Chen, J., Wang, W., Zang, L., Zhao, J., Li, W., & Jiang, T. (2016). Repression of a chromatin modifier aggravates lipopolysaccharide-induced acute lung injury in mouse. Biochemical and Biophysical Research Communications, 472(2), 362-368. https://doi.org/10.1016/j.bbrc.2016.02.043
Yin, T., Zhang, Z., Cao, B., Duan, Q., Shi, P., Zhao, H., Camara, S. N., Shen, Q., & Wang, C. (2016). Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine. Oncotarget, 7(19), 27338-27349. https://doi.org/10.18632/oncotarget.9293
Sun, Z., Zhou, D., Xie, X., Wang, S., Wang, Z., Zhao, W., Xu, H., & Zheng, L. (2016). Cross-talk between macrophages and atrial myocytes in atrial fibrillation. Basic Research in Cardiology, 111(6). https://doi.org/10.1007/s00395-016-0584-z
Yan, H., Wang, S., Li, Z., Zhao, W., Wang, Z., Sun, Z., & Pan, Y. (2016). Upregulation of miRNA-155 expression by OxLDL in dendritic cells involves JAK1/2 kinase and transcription factors YY1 and MYB. International Journal of Molecular Medicine, 37(4), 883-890. https://doi.org/10.3892/ijmm.2016.2427
Zhang, B., Shimada, Y., Kuroyanagi, J., & Ariyoshi, M. (2015). In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5 (3). Biomaterials, 52, 14-25. https://doi.org/10.1016/j.biomaterials.2015.02.043
Shiu, S. Y., Leung, W. Y., Tam, C. W., Liu, V. W., & Yao, K. M. (2012). Melatonin MT1 receptor-induced transcriptional up-regulation of p27Kip1 in prostate cancer antiproliferation is mediated via inhibition of constitutively active nuclear factor kappa B (NF-κB): potential implications on prostate cancer chemoprevention and therapy. Journal of Pineal Research, 53(2), 168-177. https://doi.org/10.1111/j.1600-079X.2012.01026.x
Ma, J., Wei, M., Wang, Q., Li, J., Wang, H., Liu, W., Lacefield, J. C., Greer, P. A., Karmazyn, M., Fan, G. C., & Peng, T. (2012). Deficiency of Capn4 gene inhibits nuclear factor-κB (NF-κB) protein signaling/inflammation and reduces remodeling after myocardial infarction. Journal of Biological Chemistry, 287(33), 27480-27489. https://doi.org/10.1074/jbc.M112.365691
Li, Y., Ma, J., Zhu, H., Singh, M., Hill, D., Greer, P. A., Arnold, J. M., Abel, E. D., & Peng, T. (2011). Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes. Diabetes, 60(11), 2985-2994. https://doi.org/10.2337/db11-0702

TF ELISA Kits

NRF2 ELISA

Shetty, A. K., Attaluri, S., Kodali, M., Shuai, B., Shetty, G. A., Upadhya, D., Hattiangady, B., Madhu, L. N., Upadhya, R., Bates, A., & Rao, X. (2020). Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness. Redox Biology, 28, 101389. https://doi.org/10.1016/j.redox.2019.101389
Shetty, G. A., Hattiangady, B., Upadhya, D., Bates, A., Attaluri, S., Shuai, B., Kodali, M., & Shetty, A. K. (2017). Chronic oxidative stress, mitochondrial dysfunction, NRF2 activation and inflammation in the hippocampus accompany heightened systemic inflammation and oxidative stress in an animal model of Gulf War Illness. Frontiers in Molecular Neuroscience, 10. https://doi.org/10.3389/fnmol.2017.00182
Song, D., Song, G., Niu, Y., Song, W., Wang, J., Yu, L., Yang, J., Lv, X., Steinberg, H., Liu, S. F., & Wang, B. (2014). Ulinastatin activates haem oxygenase 1 antioxidant pathway and attenuates allergic inflammation. British Journal of Pharmacology, 171(19), 4399–4412. https://doi.org/10.1111/bph.12780
Javkhedkar, A. A., & Banday, A. A. (2015). Antioxidant resveratrol restores renal sodium transport regulation in SHR. Physiological Reports, 3(11). https://doi.org/10.14814/phy2.12618

STAT3 ELISA

Salameh, J. W., Kumar, S., Rivera-Cruz, C. M., & Figueiredo, M. L. (2022). A second-generation Nanoluc-IL27 fusion cytokine for targeted-gene-therapy applications. Bioengineering, 9(2), 77. https://doi.org/10.3390/bioengineering9020077
Ding, C., Chen, X., Dascani, P., Hu, X., Bolli, R., Zhang, H., Mcleish, K. R., & Yan, J. (2016). STAT3 signaling in B cells is critical for germinal center maintenance and contributes to the pathogenesis of murine models of lupus. The Journal of Immunology, 196(11), 4477–4486. https://doi.org/10.4049/jimmunol.1502043

STAT1 ELISA

Salameh, J. W., Kumar, S., Rivera-Cruz, C. M., & Figueiredo, M. L. (2022). A second-generation Nanoluc-IL27 fusion cytokine for targeted-gene-therapy applications. Bioengineering, 9(2), 77. https://doi.org/10.3390/bioengineering9020077

STAT1/STAT3 ELISA

Salameh, J. W., Kumar, S., Rivera-Cruz, C. M., & Figueiredo, M. L. (2022). A second-generation Nanoluc-IL27 fusion cytokine for targeted-gene-therapy applications. Bioengineering, 9(2), 77. https://doi.org/10.3390/bioengineering9020077

TFEB ELISA

McNeill, A., Magalhaes, J., Shen, C., Chau, K.-Y., Hughes, D., Mehta, A., Foltynie, T., Cooper, J. M., Abramov, A. Y., Gegg, M., & Schapira, A. H. V. (2014). Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked parkinson disease cells. Brain, 137(5), 1481–1495. https://doi.org/10.1093/brain/awu020

PPARγ ELISA

Rahardjo, B., Widjajanto, E., Sujuti, H., & Keman, K. (2014). Curcumin decreased level of proinflammatory cytokines in monocyte cultures exposed to preeclamptic plasma by affecting the transcription factors NF-ΚB and PPAR-γ. Biomarkers and Genomic Medicine, 6(3), 105–115. https://doi.org/10.1016/j.bgm.2014.06.002

Smad1/5/8 ELISA

Julier, Z., Karami, R., Nayer, B., Lu, Y.-Z., Park, A. J., Maruyama, K., Kuhn, G. A., Müller, R., Akira, S., & Martino, M. M. (2020). Enhancing the regenerative effectiveness of growth factors by local inhibition of interleukin-1 receptor signaling. Science Advances, 6(24). https://doi.org/10.1126/sciadv.aba7602

Smad2/3 ELISA

Xia, M., Liu, J., Liu, S., Chen, K., Lin, H., Jiang, M., Xu, X., Xue, Y., Liu, W., Gu, Y., Zhang, X., Li, Z., Yi, L., Qian, Y., Zhou, C., Li, R., Zhang, X., Li, Z., & Cao, X. (2017). Ash1l and LNC-Smad3 coordinate smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity. Nature Communications, 8(1). https://doi.org/10.1038/ncomms15818

NFκB p65 ELISA

Dunn, S. L., Vera, D. L., Weaver, K. F., & Garcia, J. V. (2021). Relationships between inflammatory and metabolic markers, exercise, and body composition in young individuals. Journal of Clinical and Translational Research, 7(3), 289–296.
Yu, H., Shi, L., Qi, G., Zhao, S., Gao, Y., & Li, Y. (2016). Gypenoside protects cardiomyocytes against ischemia-reperfusion injury via the inhibition of mitogen-activated protein kinase mediated nuclear factor kappa B pathway in vitro and in vivo. Frontiers in Pharmacology, 7. https://doi.org/10.3389/fphar.2016.00148
Ma, J., Wei, M., Wang, Q., Li, J., Wang, H., Liu, W., Lacefield, J. C., Greer, P. A., Karmazyn, M., Fan, G.-C., & Peng, T. (2012). Deficiency of CAPN4 gene inhibits nuclear factor-κB (NF-κB) protein signaling/inflammation and reduces remodeling after myocardial infarction. Journal of Biological Chemistry, 287(33), 27480–27489. https://doi.org/10.1074/jbc.m112.358929

NFκB p50 ELISA

Dunn, S. L., Vera, D. L., Weaver, K. F., & Garcia, J. V. (2021). Relationships between inflammatory and metabolic markers, exercise, and body composition in young individuals. Journal of Clinical and Translational Research, 7(3), 289–296.
Haque, M., Song, J., Fino, K., Wang, Y., Sandhu, P., Song, X., Norbury, C., Ni, B., Fang, D., Salek-Ardakani, S., & Song, J. (2016). C-MYC regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection. Open Biology, 6(1), 150208. https://doi.org/10.1098/rsob.150208
Rahardjo, B., Widjajanto, E., Sujuti, H., & Keman, K. (2014). Curcumin decreased level of proinflammatory cytokines in monocyte cultures exposed to preeclamptic plasma by affecting the transcription factors NF-ΚB and PPAR-γ. Biomarkers and Genomic Medicine, 6(3), 105–115. https://doi.org/10.1016/j.bgm.2014.06.002

Cited in Research, Specific Product Unspecified

Madhu, L. N., Kodali, M., Attaluri, S., Shuai, B., Melissari, L., Rao, X., & Shetty, A. K. (2021). Melatonin improves brain function in a model of chronic Gulf War illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus. Redox Biology, 40, 101973. https://doi.org/10.1016/j.redox.2021.101973
Julier, Z., Karami, R., Nayer, B., Lu, Y.-Z., Park, A. J., Maruyama, K., Kuhn, G. A., Müller, R., Akira, S., & Martino, M. M. (2020). Enhancing the regenerative effectiveness of growth factors by local inhibition of interleukin-1 receptor signaling. Science Advances, 6(24). https://doi.org/10.1126/sciadv.abb3096
Javkhedkar, A. A., & Banday, A. A. (2015). Antioxidant resveratrol restores renal sodium transport regulation in SHR. Physiological Reports, 3(11), e12618. https://doi.org/10.14814/phy2.12618
Cao, H., Luo, S., Xu, M., Zhang, Y., Song, S., Wang, S., Kong, X., … & Zhang, X. (2014). The secondary bile acid, deoxycholate accelerates intestinal adenoma–adenocarcinoma sequence in Apc^min/+ mice through enhancing Wnt signaling. Familial Cancer.
Rahardjo, B., Widjajanto, E., Sujuti, H., & Keman, K. (2014). Curcumin decreased level of proinflammatory cytokines in monocyte cultures exposed to preeclamptic plasma by affecting the transcription factors NF-κB and PPAR-γ. Biomarkers and Genomic Medicine.
McNeill, A., Magalhaes, J., Shen, C., Chau, K. Y., Hughes, D., Mehta, A., Foltynie, T., Cooper, J. M., Abramov, A. Y., Gegg, M., & Schapira, A. H. (2014). Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells. Brain. Advance online publication. https://doi.org/10.1093/brain/awt367

TF Luciferase Reporter Vectors

Chiu, C.-W., Yang, C.-H., Tsai, J.-H., Hsieh, C.-Y., & Huang, S.-Y. (2021). Platonin, a cyanine photosensitizing dye, ameliorates inflammatory responses in vascular smooth muscle cells by modulating inflammatory transcription factors. Applied Sciences, 11(3), 1130. https://doi.org/10.3390/app11031130
Okamura, M., Shizu, R., Abe, T., Kodama, S., Hosaka, T., Sasaki, T., & Yoshinari, K. (2020). PXR functionally interacts with NF-κB and AP-1 to downregulate the inflammation-induced expression of chemokine CXCL2 in mice. Cells, 10(9), 2296. https://doi.org/10.3390/cells9102296
Ning, Z., Li, Z., Lee, P. L., Lee, S. T., ... (2018). EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-driven prostate cancer. Cell Reports.
Khan, N. M., Momin, A., Ahmed, S. H., & Haider, M. T. (2018). Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis. Free Radical Biology and Medicine. https://doi.org/10.1016/j.freeradbiomed.2018.01.013
Li, X., Mishra, P., Tang, W., Putluri, V., Dorsey, T. H., ... & Ambs, S. (2017). ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming. Journal of Clinical Investigation, 128(1), 323–340. https://doi.org/10.1172/jci93815
Noma, N., Fujii, G., Miyamoto, S., Komiya, M., Nakanishi, R., Shimura, M., Tanuma, S., & Mutoh, M. (2017). Impact of acetazolamide, a carbonic anhydrase inhibitor, on the development of intestinal polyps in Min mice. International Journal of Molecular Sciences, 18(4), 851. https://doi.org/10.3390/ijms18040851
Chuang, T. D., & Khorram, O. (2017). Glucocorticoids regulate MiR-29c levels in vascular smooth muscle cells through transcriptional and epigenetic mechanisms. Life Sciences, 186, 87-91. https://doi.org/10.1016/j.lfs.2017.08.007
Persad, A., Venkateswaran, G., Hao, L., Garcia, M. E., Yoon, J., Sidhu, J., & Persad, S. (2017). Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A. Genes & Cancer. https://doi.org/10.18632/genesandcancer.128
Inoue, S., et al. (2018). ATF2 promotes urothelial cancer outgrowth via cooperation with androgen receptor signaling. Endocrine Connections, 7, 1397–1408. https://doi.org/10.1530/ec-18-0364
Mishra, P., Tang, W., Putluri, V., Dorsey, T. H., Jin, F., Wang, F., ... & Ambs, S. (2017). ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming. Journal of Clinical Investigation, 128(1), 323–340. https://doi.org/10.1172/jci93815
Bhattacharyya, S., Feferman, L., Borthakur, S., & Tobacman, J. K. (2014). Common food additive carrageenan stimulates Wnt/β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction. Nutr Cancer, 66(1), 117-127.
Sun, X., Kumar, S., Sharma, S., Aggarwal, S., Lu, Q., Gross, C., Rafikova, O., Lee, S. G., Dasarathy, S., Hou, Y., Meadows, M. L., Han, W., Su, Y., Fineman, J. R., & Black, S. M. (2014). Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial NO synthase. American Journal of Respiratory Cell and Molecular Biology, 51(1), 31-40. https://doi.org/10.1165/rcmb.2013-0450OC
Dong, H., You, S. H., Williams, A., Wade, M. G., Yauk, C. L., & Thomas, R. Z. (2014). Transient maternal hypothyroxinemia potentiates the transcriptional response to exogenous thyroid hormone in the fetal cerebral cortex before the onset of fetal thyroid function: A messenger and microRNA profiling study. Cerebral Cortex, 24(2), 456-466. https://doi.org/10.1093/cercor/bhs322
Chuang, T. D., & Khorram, O. (2014). The regulatory function of miR-200c on inflammatory and cell-cycle associated genes in SK-LMS-1, a leiomyosarcoma cell line. Reproductive Sciences, 21(1), 24-35. https://doi.org/10.1177/1933719113493935
Gordillo, G. M., Biswas, A., Khanna, S., Pan, X., Sinha, M., Roy, S., & Sen, C. K. (2014). Dicer knockdown inhibits endothelial cell tumor growth via microRNA 21a-3p targeting of Nox-4. Journal of Biological Chemistry, 289(11), 7718-7730. https://doi.org/10.1074/jbc.M113.524920
Sebastián, C., Zwaans, B. M., Silberman, D. M., Gymrek, M., Goren, A., Zhong, L., Ram, O., Truelove, J., Guimaraes, A. R., Toiber, D., Cosentino, C., Greenson, J. K., MacDonald, A. I., McGlynn, L., Maxwell, F., Edwards, J., Giacosa, S., Guccione, E., Weissleder, R., Bernstein, B. E., Regev, A., Shiels, P. G., Lombard, D. B., & Mostoslavsky, R. (2012). The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell, 151(6), 1185-1199. https://doi.org/10.1016/j.cell.2012.10.024
Peluso, J. J., Decerbo, J., & Lodde, V. (2012). Evidence for a genomic mechanism of action for progesterone receptor membrane component-1. Steroids, 77(10), 1007-1012. https://doi.org/10.1016/j.steroids.2012.07.015
Bondeva, T., Heinzig, J., Ruhe, C., & Wolf, G. (2013). Advanced glycated end products affect HIF- transcriptional activity in renal cells. Molecular Endocrinology, 27(1), 93-106. https://doi.org/10.1210/me.2012-1327
Persad, A., Venkateswaran, G., Hao, L., Garcia, M. E., Yoon, J., Sidhu, J., & Persad, S. (2013). Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A. Genes & Cancer. https://doi.org/10.18632/genesandcancer.128
M Cormier, F Ghouili, P Roumaud, & W Bauer. (2017). Influences of flavones on cell viability and cAMP-dependent steroidogenic gene regulation in MA-10 Leydig cells. Cell Biology and Toxicology. https://doi.org/10.1007/s10565-017-9395-8
Li, X., Mishra, P., Tang, W., Putluri, V., Dorsey, T. H., Jin, F., Wang, F., & Ambs, S. (2017). ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming. Journal of Clinical Investigation, 128(1), 323-340. https://doi.org/10.1172/jci93815
Souza, P. S., Madigan, J. P., Gilleta, J. P., Kapoor, K., & others. (2015). Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL. Experimental Cell Research. https://doi.org/10.1016/j.yexcr.2015.06.018
Chuang, T. D., & Khorram, O. (2014). The regulatory function of miR-200c on inflammatory and cell-cycle associated genes in SK-LMS-1, a leiomyosarcoma cell line. Reproductive Sciences, 21(1), 24-35. https://doi.org/10.1177/1933719113493935
Lin, C., Koval, A., Tishchenko, S., Gabdulkhakov, A., Tin, U., Solis, G. P., & Katanaev, V. L. (2014). Double suppression of the Gα protein activity by RGS proteins. Molecular Cell, 53(4), 663-671. https://doi.org/10.1016/j.molcel.2014.01.027

Cytokines ELISA

Cytokine ELISA Plate Arrays

Mouse Cytokine ELISA Plate Array I (Chemiluminescence) (EA-4003)

McMahon, C. L., Castro, J., Silvas, J., Muniz Perez, A., Estrada, M., Carrion, R. Jr., & Hsieh, J. (2023). Fetal brain vulnerability to SARS-CoV-2 infection. Brain, Behavior, and Immunity, 112, 188-205. https://doi.org/10.1016/j.bbi.2023.06.015
Varga-Medveczky, Z., Kovács, N., Tóth, M. E., Sántha, M., Horváth, I., Bors, L. A., Fónagy, K., Imre, T., Szabó, P., Máthé, D., & Erdő, F. (2021). Age-related inflammatory balance shift, nasal barrier function, and cerebro-morphological status in healthy and diseased rodents. Frontiers in Neuroscience, 15. https://doi.org/10.3389/fnins.2021.700729
Kosar, K., Cornuet, P., Singh, S., Lee, E., Liu, S., Gayden, J., Sato, T., Freyberg, Z., Arteel, G., & Nejak‐Bowen, K. (2021). WNT7B regulates cholangiocyte proliferation and function during murine cholestasis. Hepatology Communications, 5(12), 2019–2034. https://doi.org/10.1002/hep4.1784
Kennedy, L., Meadows, V., Demieville, J., Hargrove, L., Virani, S., Glaser, S., Zhou, T., Rinehart, E., Jaeger, V., Kyritsi, K., Pham, L., Alpini, G., & Francis, H. (2020). Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking L-histidine decarboxylase/histamine signaling. Laboratory Investigation, 100(6), 837–848. https://doi.org/10.1038/s41374-020-0405-8
Lu, J.-S., Song, Q., Zhang, M.-M., & Zhuo, M. (2018). No requirement of interleukin-1 for long-term potentiation in the anterior cingulate cortex of adult mice. Molecular Pain, 14. https://doi.org/10.1177/1744806918765799
García-Mendoza, M. G., Inman, D. R., Ponik, S. M., Jeffery, J. J., Sheerar, D. S., Van Doorn, R. R., & Keely, P. J. (2016). Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment. Breast Cancer Research, 18(1). https://doi.org/10.1186/s13058-016-0703-7
An, S. S., Chi, K.-W., Kang, S. C., Dubey, A., Park, D. W., Kwon, J. E., Jeong, Y. J., Kim, T., & Kim, I. (2015). Investigation of the biological and anti-cancer properties of ellagic acid-encapsulated nano-sized Metalla-cages. International Journal of Nanomedicine, 10, 227-237. https://doi.org/10.2147/ijn.s88289

Mouse Cytokine ELISA Plate Array I (Colorimetric) (EA-4005)

Kosar, K., Cornuet, P., Singh, S., Lee, E., Liu, S., Gayden, J., Sato, T., Freyberg, Z., Arteel, G., & Nejak‐Bowen, K. (2021). WNT7B regulates cholangiocyte proliferation and function during murine cholestasis. Hepatology Communications, 5(12), 2019–2034. https://doi.org/10.1002/hep4.1784
Kennedy, L., Meadows, V., Demieville, J., Hargrove, L., Virani, S., Glaser, S., Zhou, T., Rinehart, E., Jaeger, V., Kyritsi, K., Pham, L., Alpini, G., & Francis, H. (2020). Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking L-histidine decarboxylase/histamine signaling. Laboratory Investigation, 100(6), 837–848. https://doi.org/10.1038/s41374-020-0405-8
Kyritsi, K., Francis, H., Zhou, T., Ceci, L., Wu, N., Yang, Z., Meng, F., Chen, L., Baiocchi, L., Kundu, D., Kennedy, L., Liangpunsakul, S., Wu, C., Glaser, S., & Alpini, G. (2020). Downregulation of p16 decreases biliary damage and liver fibrosis in the MDR2/ mouse model of primary sclerosing cholangitis. Gene Expression, 20(2), 89–103. https://doi.org/10.3727/105221620x15889714507961
Gurien, S. D., Aziz, M., Jin, H., Wang, H., He, M., Al‐Abed, Y., Nicastro, J. M., Coppa, G. F., & Wang, P. (2019). Extracellular Microrna 130b‐3p inhibits ecirp‐induced inflammation. EMBO Reports, 21(1). https://doi.org/10.15252/embr.201948075
Harun-Or-Rashid, M., & Inman, D. M. (2018). Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. Journal of Neuroinflammation, 15(1). https://doi.org/10.1186/s12974-018-1346-7
An, S. S., Chi, K.-W., Kang, S. C., Dubey, A., Park, D. W., Kwon, J. E., Jeong, Y. J., Kim, T., & Kim, I. (2015). Investigation of the biological and anti-cancer properties of ellagic acid-encapsulated nano-sized Metalla-cages. International Journal of Nanomedicine, 10, 227–237. https://doi.org/10.2147/ijn.s88289

Human Cytokine ELISA Plate Array I (Chemiluminescence) (EA-4001)

Ciccone, V., Terzuoli, E., Ristori, E., Filippelli, A., Ziche, M., Morbidelli, L., & Donnini, S. (2022). ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade. International Journal of Molecular Medicine, 50, 99. https://doi.org/10.3892/ijmm.2022.5155
Kim, K., Kim, H., & Sung, G. Y. (2022). An Interleukin-4 and Interleukin-13 induced atopic dermatitis human skin equivalent model by a skin-on-a-chip. International Journal of Molecular Sciences, 23(4), 2116. https://doi.org/10.3390/ijms23042116
Terzuoli, E., Bellan, C., Aversa, S., Ciccone, V., Morbidelli, L., Giachetti, A., Donnini, S., & Ziche, M. (2019). Overexpression in melanoma and lung tumors drives cancer stem cell expansion, impairing immune surveillance through enhanced PD-L1 output. Cancers, 11(12), 1963. https://doi.org/10.3390/cancers11121963
Ciccone, V., Terzuoli, E., Donnini, S., Giachetti, A., Morbidelli, L., & Ziche, M. (2018). ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signaling in MCF-7 breast cancer cells. Journal of Experimental & Clinical Cancer Research, 37(1). https://doi.org/10.1186/s13046-018-0975-0
Luo, Z., Ge, M., Chen, J., Geng, Q., Tian, M., Qiao, Z., Bai, L., Zhang, Q., Zhu, C., Xiong, Y., Wu, K., Liu, F., Liu, Y., & Wu, J. (2017). Hrs plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection. PLOS Pathogens, 13(8). https://doi.org/10.1371/journal.ppat.1006585
Liu, Z., Thomas, V., Wright, J. L., Takita, C., Poitevien, M., Abreu-Molnar, D., Zhao, W., Reis, I., & Hu, J. (2012). Abstract 4352: Radiotherapy-induced plasma cytokine changes and skin toxicity in breast cancer patients. Cancer Research, 72(8 Supplement), 4352–4352. https://doi.org/10.1158/1538-7445.am2012-4352

Human Cytokine ELISA Plate Array I (Colorimetric) (EA-4002)

Kim, K., Kim, H., & Sung, G. Y. (2022). An interleukin-4 and interleukin-13 induced atopic dermatitis human skin equivalent model by a skin-on-a-chip. International Journal of Molecular Sciences, 23(4), 2116. https://doi.org/10.3390/ijms23042116
Luo, Z., Ge, M., Chen, J., Geng, Q., Tian, M., Qiao, Z., Bai, L., Zhang, Q., Zhu, C., Xiong, Y., Wu, K., Liu, F., Liu, Y., & Wu, J. (2017). Hrs plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection. PLOS Pathogens, 13(8). https://doi.org/10.1371/journal.ppat.1006585
Joshi, A. R., Holtmann, L., Bobylev, I., Schneider, C., Ritter, C., Weis, J., & Lehmann, H. C. (2016). Loss of Schwann cell plasticity in chronic inflammatory demyelinating polyneuropathy (CIDP). Journal of Neuroinflammation, 13(1). https://doi.org/10.1186/s12974-016-0711-7
Liu, Z., Thomas, V., Wright, J. L., Takita, C., Poitevien, M., Abreu-Molnar, D., Zhao, W., Reis, I., & Hu, J. (2012). Abstract 4352: Radiotherapy-induced plasma cytokine changes and skin toxicity in breast cancer patients. Cancer Research, 72(8 Supplement), 4352–4352. https://doi.org/10.1158/1538-7445.am2012-4352

Human Cytokine ELISA Plate Array IV (Colorimetric) (EA-4015)

Thomas, G., Frederick, E., Thompson, L., Bar-Or, R., Mulugeta, Y., Hausburg, M., Roshon, M., Mains, C., & Bar-Or, D. (2020). LMWF5A suppresses cytokine release by modulating select inflammatory transcription factor activity in stimulated PBMC. Journal of Translational Medicine, 18(1). https://doi.org/10.1186/s12967-020-02626-z

Human Angiogenesis ELISA Plate Array (Colorimetric) (EA-4012)

Lei, L., & Mou, Q. (2020). Exosomal taurine up-regulated 1 promotes angiogenesis and endothelial cell proliferation in cervical cancer. Cancer Biology & Therapy, 21(8), 717–725. https://doi.org/10.1080/15384047.2020.1764318
Alcendor, D. J., Charest, A. M., Zhu, W. Q., Vigil, H. E., & Knobel, S. M. (2012). Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus. Journal of Neuroinflammation, 9(1), 95. https://doi.org/10.1186/1742-2094-9-95

Rat Cytokine ELISA Plate Array (Colorimetric) (EA-4006)

Torres-Rodríguez, O., Rivera-Escobales, Y., Castillo-Ocampo, Y., Velazquez, B., Colón, M., & Porter, J. T. (2023). Purinergic P2X7 receptor-mediated inflammation precedes PTSD-related behaviors in rats. Brain, Behavior, and Immunity, 110, 107–118. https://doi.org/10.1016/j.bbi.2023.02.015

Cited in Research, Specific Product Unspecified

Messier, T., Scotland, M., Naumov, G., Dulloo, S., Fennell, D., & Cunniff, B. (2023). Effects of RSO-021 on cytokine profiles of malignant pleural effusions from patients enrolled in the MITOPE phase 1/2 clinical trial. Molecular Cancer Therapeutics, 22(12_Supplement), B022.
Trizzino, M., Zucco, A., Deliard, S., Wang, F., Barbieri, E., Veglia, F., Gabrilovich, D., & Gardini, A. (2021). EGR1 is a gatekeeper of inflammatory enhancers in human macrophages. Science Advances, 7(3), eaaz8836. https://doi.org/10.1126/sciadv.aaz8836
Merkhan, M. M., Shephard, M. T., & Forsyth, N. R. (2021). Physoxia alters human mesenchymal stem cell secretome. Journal of Tissue Engineering. https://doi.org/10.1177/20417314211056132
Lu, K.-Y., Lin, S.-Z., Dass, K. T. P., Lin, W.-J., Liu, S.-P., & Harn, H.-J. (2021). 3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells. Biomedicine & Pharmacotherapy, 139, 111687. https://doi.org/10.1016/j.biopha.2021.111687
Wilson, A., Velasco, C. A., Herbert, G. W., Lucas, S. N., Sanchez, B. N., Cerrato, J. M., Spilde, M., Li, Q.-Z., Campen, M. J., & Zychowski, K. E. (2021). Mine-site derived particulate matter exposure exacerbates neurological and pulmonary inflammatory outcomes in an autoimmune mouse model. Journal of Toxicology and Environmental Health, Part A. https://doi.org/10.1080/15287394.2021.1891488
Pruett, N., Singh, A., Shankar, A., Schrump, D. S., & Hoang, C. D. (2020). Normal mesothelial cell lines newly derived from human pleural biopsy explants. American Journal of Physiology-Lung Cellular and Molecular Physiology. https://doi.org/10.1152/ajplung.00141.2020
Hartley, A., Wang, B., Mundade, R., et al. (2020). PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer. Scientific Reports, 10, 15934. https://doi.org/10.1038/s41598-020-72942-3
Bors, L. A., & Franciska, V. D. E. (2020). Effects of intravenous and intranasal P-glycoprotein modulation on the blood-brain barrier in young and aging rats. [PhD Dissertation]. Pázmány Péter Catholic University.
Cassetta, L., et al. (2019). Human tumor-associated macrophage and monocyte transcriptional landscapes reveal cancer-specific reprogramming, biomarkers, and therapeutic targets. Cancer Cell. https://doi.org/10.1016/j.ccell.2019.02.009
López, J. F., Sarkanen, J.-R., Huttala, O., Kaartinen, I. S., Kuokkanen, H. O., & Ylikomi, T. (2018). Adipose tissue extract shows potential for wound healing: In vitro proliferation and migration of cell types contributing to wound healing in the presence of adipose tissue preparation and platelet rich plasma. Cytotechnology. https://doi.org/10.1007/s10616-018-0211-y
Yun, S. P., et al. (2018). Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease. Nature Medicine. https://doi.org/10.1038/s41591-018-0051-5
Lange, J., et al. (2018). Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis. Acta Neuropathologica Communications, 6(1). https://doi.org/10.1186/s40478-018-0575-4
Kruse, C. R., Sakthivel, D., Sinha, I., Helm, D., Sørensen, J. A., Eriksson, E., & Nuutila, K. (2018). Evaluation of the efficacy of cell and micrograft transplantation for full-thickness wound healing. Journal of Surgical Research, 227, 35–43. https://doi.org/10.1016/j.jss.2018.02.004
Yamamoto, K., Yamamoto, T., Honjo, K., & Ichioka, H. (2015). Electrical stimulation with periodic alternating intervals stimulates neuronal cells to produce neurotrophins and cytokines through activation of mitogen-activated protein kinase pathways. European Journal of Oral Sciences. https://doi.org/10.1111/eos.12224
Iskender, B., Izgi, K., Sakalar, C., & Canatan, H. (2015). Priming hMSCs with a putative anti-cancer compound, myrtucommulone-a: A way to harness hMSC cytokine expression via modulating PI3K/Akt pathway? Tumor Biology. https://doi.org/10.1007/s13277-015-3443-8
Radoshevich, L., Impens, F., Ribet, D., & Quereda, J. J. (2015). SG15 counteracts Listeria monocytogenes infection. eLife, 4, e06848. https://doi.org/10.7554/eLife.06848
Miyake, K., Adachi, K., Watanabe, M., Sasatomi, Y., et al. (2014). Parasites alter the pathological phenotype of lupus nephritis. Autoimmunity, 47(8), 538-547. https://doi.org/10.3109/08916934.2014.929669
Hanzel, C. E., Pichet-Binette, A., Pimentel, L. S. B., & Iulita, M. F. (2014). Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer's disease. Neurobiology of Aging, 35(10), 2249-2262. https://doi.org/10.1016/j.neurobiolaging.2014.03.026
Nakayama, R., Kuroda, J., Taniyama, N., Yamamoto-Sugitani, M., Wada, S., Kiyota, M., Mizutani, S., Chinen, Y., Matsumoto, Y., Nagoshi, H., Shimura, Y., Kobayashi, T., Horiike, S., Sato, K., & Taniwaki, M. (2014). Suppression of SERPINA1-albumin complex formation by Galectin-3 overexpression leads to paracrine growth promotion of chronic myelogenous leukemia cells. Leukemia Research, 38(1), 103-108. https://doi.org/10.1016/j.leukres.2013.09.018
Ouyang, B., Sun, X., Han, D., Chen, S., Yao, B., Gao, Y., Bian, J., et al. (2014). Human urine-derived stem cells alone or genetically-modified with FGF2 improve type 2 diabetic erectile dysfunction in a rat model. PLOS ONE. https://doi.org/10.1371/journal.pone.0092825
Marks, L. R., Davidson, B. A., Knight, P. R., & Hakansson, A. P. (2013). Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease. mBio, 4(4), e00438-13. https://doi.org/10.1128/mBio.00438-13
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Forrest, C. M., Khalil, O. S., Pisar, M., Darlington, L. G., & Stone, T. W. (2013). Prenatal inhibition of the tryptophan-kynurenine pathway alters synaptic plasticity and protein expression in the rat hippocampus. Brain Research, 1504,

Human Cytokine ELISA Strips

Human Inflammation ELISA Strip (Chemiluminescence) (EA-1621)

Worku, M., Abdalla, A., Adjei-Fremah, S., & Ismail, H. (2016). The impact of diet on expression of genes involved in innate immunity in goat blood. Journal of Agricultural Science, 8(3), 1. https://doi.org/10.5539/jas.v8n3p1
Mayer, J. P., Kasniunas, A., McCarty, R. D., Schwartz, S. N., Yue, B. Y. J. T., & Knepper, P. A. (2011). Toll-like receptor 4, low molecular weight hyaluronic acid and cytokine response in trabecular meshwork cells. Investigative Ophthalmology & Visual Science, 52(14), 4652.

Human Angiogenesis ELISA Strip II (Chemiluminescence) (EA-1631)

Chanakira, A., Dutta, R., Charboneau, R., Barke, R., Santilli, S. M., & Roy, S. (2012). Hypoxia differentially regulates arterial and venous smooth muscle cell proliferation via PDGFR-β and VEGFR-2 expression. American Journal of Physiology-Heart and Circulatory Physiology, 302(5). https://doi.org/10.1152/ajpheart.00411.2011

Human Inflammation ELISA Strip (Colorimetric) (EA-1031)

Worku, M., Abdalla, A., Adjei-Fremah, S., & Ismail, H. (2016). The impact of diet on expression of genes involved in innate immunity in goat blood. Journal of Agricultural Science, 8(3), 1. https://doi.org/10.5539/jas.v8n3p1
Mayer, J. P., Kasniunas, A., McCarty, R. D., Schwartz, S. N., Yue, B. Y. J. T., & Knepper, P. A. (2011). Toll-like receptor 4, low molecular weight hyaluronic acid, and cytokine response in trabecular meshwork cells. Investigative Ophthalmology & Visual Science, 52(14), 4652. https://doi.org/10.1167/iovs.11-8138

Cited in Research, Specific Product Unspecified

Kim, H. Y., Kim, T. J., Kang, L., Kim, Y.-J., Kang, M. K., Kim, J., Ryu, J. H., Hyeon, T., Yoon, B.-W., Ko, S.-B., & Kim, B.-S. (2020). Mesenchymal stem cell-derived magnetic extracellular nanovesicles for targeting and treatment of ischemic stroke. Biomaterials, 119942. https://doi.org/10.1016/j.biomaterials.2020.119942
Sawant, A. S., Jain, R., Patil, S. S., Khedkar, V. M., & Kadam, S. K. (2019). Synthesis and evaluation of a novel series of 6-bromo-1-cyclopentyl-1H-indazole-4-carboxylic acid-substituted amide derivatives as anticancer, antiangiogenic, and antioxidant agents. Medicinal Chemistry Research, 28(8), 1135–1147. https://doi.org/10.1007/s00044-019-02454-x
Xu, L., Yu, Y., Li, J., Zhao, Y., Jiang, X., Jiang, S., Sun, Y., Li, X., Liu, Y., & Li, X. (2019). Reseeding endothelial cells with fibroblasts to improve the re-endothelialization of pancreatic acellular scaffolds. Journal of Materials Science: Materials in Medicine, 30(7), 92. https://doi.org/10.1007/s10856-019-6287-x
López, J. F., Sarkanen, J.-R., Huttala, O., Kaartinen, I. S., Kuokkanen, H. O., & Ylikomi, T. (2018). Adipose tissue extract shows potential for wound healing: In vitro proliferation and migration of cell types contributing to wound healing in the presence of adipose tissue preparation and platelet rich plasma. Cytotechnology, 70(6), 1611–1623. https://doi.org/10.1007/s10616-018-0211-y
Fortunato, O., Basso, M., Garcia-Bates, S., Soria, M., & García-Arranz, M. (2018). Circulating miR-320a promotes immunosuppressive macrophages M2 phenotype associated with lung cancer risk. International Journal of Cancer, 143(5), 1131–1140. https://doi.org/10.1002/ijc.31988
Wise, L. M., Latham, J. A., Khoury, N. M., Mies, R. M., & Lopez, M. P. (2018). Perinatal high-fat diet and bisphenol A: Effects on behavior and gene expression in the medial prefrontal cortex. Developmental Neuroscience, 40(1–2), 1–16. https://doi.org/10.1159/000494879
Fortunato, T. M., Beltrami, C., Emanueli, C., Paul, A., & Pula, G. (2016). Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: Tissue engineering implications. Scientific Reports, 6, 25326. https://doi.org/10.1038/srep25326
Wang, P., Henning, S. M., Magyar, C. E., Elshimali, Y., Heber, D., & Vadgama, J. V. (2016). Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy. Journal of Experimental & Clinical Cancer Research, 35(1), 73. https://doi.org/10.1186/s13046-016-0351-x
Kamble, V. T., Sawant, A. S., Sawant, S. S., & Pisal, P. M. (2015). Synthesis and evaluation of new 4-chloro-2-(3-chloro-4-fluorophenyl)-5-(aliphatic/cyclic saturated amino)pyridazin-3(2H)-one derivatives as anticancer, antiangiogenic, and antioxidant agents. Archiv der Pharmazie, 348(5), 338–346. https://doi.org/10.1002/ardp.201400306
Lecce, L., Lam, Y. T., Lindsay, L. A., Yuen, S. C., Simpson, P. J. L., Handelsman, D. J., & Ng, M. K. C. (2014). Aging impairs VEGF-mediated, androgen-dependent regulation of angiogenesis. Molecular Endocrinology, 28(8), 1230–1244. https://doi.org/10.1210/me.2013-1405
Chen, J., Zhao, Y., Chen, S., Wang, J., Xiao, X., Ma, X., Penchikala, M., Xia, H., Lazartigues, E., Zhao, B., & Chen, Y. (2014). Neuronal over-expression of ACE2 protects brain from ischemia-induced damage. Neuropharmacology, 79, 550–558. https://doi.org/10.1016/j.neuropharm.2014.01.016
Durand, L. A. H., Góngora, A., López, J. M. P., & Boccaccini, A. R. (2014). In vitro endothelial cell response to ionic dissolution products from boron-doped bioactive glass in the SiO2-CaO-P2O5-Na2O system. Journal of Materials Chemistry B, 2(37), 7620–7630. https://doi.org/10.1039/C4TB01043D
Hadi, N., Al-Amran, F., Yousif, M., & Alrekabi, M. (2014). Amelioration of myocardial ischemia/reperfusion injury by L-carnitine via downregulation of the inflammatory response and apoptosis. Experimental & Clinical Cardiology, 19(3), 1213–1223.
Ishitsuka, Y., Kawachi, Y., Maruyama, H., Taguchi, S., Fujisawa, Y., Furuta, J., Nakamura, Y., Ishii, Y., & Otsuka, F. (2013). Pituitary tumor transforming gene 1 induces tumor necrosis factor-α production from keratinocytes: Implication for involvement in the pathophysiology of psoriasis. Journal of Investigative Dermatology, 133(11), 2566–2575. https://doi.org/10.1038/jid.2013.273
Poehlmann, A., Reissig, K., Just, A., Walluscheck, D., Hartig, R., Schinlauer, A., Lessel, W., Guenther, T., Silver, A., Steinberg, P., & Roessner, A. (2013). Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis. Journal of Cellular and Molecular Medicine, 17(2), 239–252. https://doi.org/10.1111/jcmm.12079
Kawachi, Y., Maruyama, H., Ishitsuka, Y., Fujisawa, Y., Furuta, J., Nakamura, Y., Ichikawa, E., Furumura, M., & Otsuka, F. (2013). NF1 gene silencing induces upregulation of VEGF expression in both Schwann and non-Schwann cells. Experimental Dermatology, 22(4), 262–265. https://doi.org/10.1111/exd.12115
Shukla, A., Miller, J. M., Cason, C., Sayan, A. E., Macpherson, M., Beuschel, S. L., Hillegass, J. M., Vacek, P. M., Pass, H. I., & Mossman, B. T. (2013). Extracellular signal regulated kinase 5: A potential therapeutic target for malignant mesotheliomas. Clinical Cancer Research, 19(8), 2071–2083. https://doi.org/10.1158/1078-0432.CCR-12-3446
Pattullo, V., Duarte-Rojo, A., Soliman, W., Vargas-Vorackova, F., Sockalingam, S., Fantus, I. G., Allard, J., & Heathcote, J. (2013). A 24-week dietary and physical activity lifestyle intervention reduces hepatic insulin resistance in the obese with chronic hepatitis C. Liver International, 33(3), 410–419. https://doi.org/10.1111/liv.12051
Spano, D., Marshall, J. C., Marino, N., De Martino, D., Romano, A., Scoppettuolo, M. N., Bello, A. M., Di Dato, V., Navas, L., De Vita, G., Medaglia, C., Steeg, P. S., & Zollo, M. (2013). Dipyridamole prevents triple-negative breast-cancer progression. Clinical & Experimental Metastasis, 30(1), 47–68. https://doi.org/10.1007/s10585-012-9443-1
García-Gareta, E., Ravindran, S., Sharma, V., Samizadeh, S., & Dye, J. F. (2013). A novel multiparameter in vitro model of three-dimensional cell ingress into scaffolds for dermal reconstruction to predict in vivo outcome. Biores Open Access, 2(6), 412–420. https://doi.org/10.1089/biores.2013.0048
Bhattacharyya, S., Xue, L., Devkota, S., Chang, E., Morris, S., & Tobacman, J. K. (2013). Carrageenan-induced colonic inflammation is reduced in Bcl10-null mice and increased in IL-10 deficient mice. Mediators of Inflammation, 2013, 397642. https://doi.org/10.1155/2013/397642
Forrest, C. M., Khalil, O. S., Pisar, M., Smith, R. A., Darlington, L. G., & Stone, T. W. (2012). Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I
) changes synaptic proteins, N-methyl-D-aspartate receptors, and neurogenesis markers in offspring. Molecular Brain, 5(1), 22. https://doi.org/10.1186/1756-6606-5-22
Shin, K. K., Lee, A. L., Kim, J. Y., Lee, S. Y., Bae, Y. C., & Jung, J. S. (2012). miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo. Biochemical and Biophysical Research Communications, 422(4), 633–638. https://doi.org/10.1016/j.bbrc.2012.05.144
Alcendor, D. J., Charest, A., Zhu, W. Q., Vigil, H. E., & Knobel, S. M. (2012). Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus. Neuroinflammation, 9, 95. https://doi.org/10.1186/1742-2094-9-95
Alcendor, D. J., Charest, A., Zhu, W. Q., Vigil, H. E., & Knobel, S. M. (2012). Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus. Neuroinflammation, 9, 95. https://doi.org/10.1186/1742-2094-9-95
Yoshizuka, N., Chen, R. M., Xu, Z., Liao, R., Hong, L., Hu, W. Y., Yu, G., Han, J., Chen, L., & Sun, P. (2012). A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis. Molecular and Cellular Biology, 32(6), 606–618. https://doi.org/10.1128/MCB.06032-11
Banga, A., Witzmann, F. A., Petrache, H. I., & Blazer-Yost, B. L. (2012). Functional effects of nanoparticle exposure on Calu-3 airway epithelial cells. Cell Physiology and Biochemistry, 29(1-2), 197–212. https://doi.org/10.1159/000339435
Yang, Z., Chevolot, Y., Ataman-Önalb, Y., Choquet-Kastylevsky, G., Souteyrand, E., & Laurenceau, E. (2011). Cancer biomarkers detection using 3D microstructured protein chip: Implementation of customized multiplex immunoassay. Sensors and Actuators B: Chemical, 162(1), 238–243. https://doi.org/10.1016/j.snb.2011.10.053
Hiesinger, W., Perez-Aguilar, J. M., Atluri, P., Marotta, N. A., Frederick, J. R., Fitzpatrick, J. R., McCormick, R. C., Muenzer, J. R., Yang, E. C., Levit, R. D., Yuan, L. J., Macarthur, J. W., Saven, J. G., & Woo, Y. J. (2011). Computational protein design to reengineer stromal cell–derived factor-1α generates an effective and translatable angiogenic polypeptide analog. Circulation, 124(12 Suppl), S18–S26. https://doi.org/10.1161/CIRCULATIONAHA.111.045275
Kluve-Beckerman, B., Hardwick, J., Du, L., Benson, M. D., Monia, B. P., Watt, A., Crooke, R. M., & Mullick, A. (2011). Antisense oligonucleotide suppression of serum amyloid A reduces amyloid deposition in mice with AA amyloidosis. Amyloid, 18(3), 136–146. https://doi.org/10.3109/13506129.2011.616241
Cheung, W. Y., Liu, C., Tonelli-Zasarsky, R. M., Simmons, C. A., & You, L. (2011). Osteocyte apoptosis is mechanically regulated and induces angiogenesis in vitro. Journal of Orthopaedic Research, 29(4), 523–530. https://doi.org/10.1002/jor.21366
Dickey, J. S., Baird, B. J., Redon, C. E., Sokolov, M. V., Sedelnikova, O. A., & Bonner, W. M. (2009). Intercellular communication of cellular stress monitored by γ-H2AX induction. Carcinogenesis, 30(10), 1686–1695. https://doi.org/10.1093/carcin/bgp200

Mouse Cytokine ELISA Strips

Mouse Obesity ELISA Strip (Chemiluminescence) (EA-1721)

Tanis, R. M., Piroli, G. G., Day, S. D., & Frizzell, N. (2015). The effect of glucose concentration and sodium phenylbutyrate treatment on mitochondrial bioenergetics and ER stress in 3T3-L1 adipocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1853(1), 213–221. https://doi.org/10.1016/j.bbamcr.2014.10.012

Mouse Cytokine ELISA Strip (Chemiluminescence) (EA-1731)

Esbona, K., Inman, D., Saha, S., Jeffery, J., Schedin, P., Wilke, L., & Keely, P. (2016). COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Research, 18(1). https://doi.org/10.1186/s13058-016-0695-3
Ban, K., Peng, Z., & Kozar, R. A. (2013). Inhibition of ERK1/2 worsens intestinal ischemia/reperfusion injury. PLoS ONE, 8(9). https://doi.org/10.1371/journal.pone.0076790
Ban, K., & Kozar, R. A. (2012). Protective role of p70s6K in intestinal ischemia/reperfusion injury in mice. PLoS ONE, 7(7). https://doi.org/10.1371/journal.pone.0041584

Mouse Angiogenesis ELISA Strip (Chemiluminescence) (EA-1701)

Cheung, W., Liu, C., Tonelli‐Zasarsky, R. M. L., Simmons, C. A., & You, L. (2010). Osteocyte apoptosis is mechanically regulated and induces angiogenesis in vitro. Journal of Orthopaedic Research, 29(4), 523–530. https://doi.org/10.1002/jor.21283

Mouse Oxidative Stress ELISA Strip (Chemiluminescence) (EA-1741)

Lange, J., Haslett, L. J., Lloyd-Evans, E., Pocock, J. M., Sands, M. S., Williams, B. P., & Cooper, J. D. (2018). Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis. Acta Neuropathologica Communications, 6(1). https://doi.org/10.1186/s40478-018-0575-4

Mouse Cytokine ELISA Strip (Colorimetric) (EA-1091)

Esbona, K., Inman, D., Saha, S., Jeffery, J., Schedin, P., Wilke, L., & Keely, P. (2016). COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Research, 18(1). https://doi.org/10.1186/s13058-016-0695-3
Salazar, N. C., Vallejos, X., Siryk, A., Rengo, G., Cannavo, A., Liccardo, D., De Lucia, C., Gao, E., Leosco, D., Koch, W. J., & Lymperopoulos, A. (2013). GRK2 blockade with βarkct is essential for cardiac β2-adrenergic receptor signaling towards increased contractility. Cell Communication and Signaling, 11(1). https://doi.org/10.1186/1478-811X-11-64
Ban, K., Peng, Z., & Kozar, R. A. (2013). Inhibition of ERK1/2 worsens intestinal ischemia/reperfusion injury. PLoS ONE, 8(9). https://doi.org/10.1371/journal.pone.0076790
Ban, K., & Kozar, R. A. (2012). Protective role of p70s6K in intestinal ischemia/reperfusion injury in mice. PLoS ONE, 7(7). https://doi.org/10.1371/journal.pone.0041584

Mouse Obesity ELISA Strip I (Colorimetric) (EA-1071)

Szőke, K., Bódi, B., Hendrik, Z., Czompa, A., Gyöngyösi, A., Haines, D. D., Papp, Z., Tósaki, Á., & Lekli, I. (2023). Rapamycin treatment increases survival, autophagy biomarkers, and expression of the anti-aging klotho protein in elderly mice. Pharmacology Research & Perspectives, 11(3), e01091. https://doi.org/10.1002/prp2.1091

Mouse Angiogenesis ELISA Strip (Colorimetric) (EA-1021)

Cheung, W., Liu, C., Tonelli‐Zasarsky, R. M. L., Simmons, C. A., & You, L. (2010). Osteocyte apoptosis is mechanically regulated and induces angiogenesis in vitro. Journal of Orthopaedic Research, 29(4), 523–530. https://doi.org/10.1002/jor.21283

Mouse Oxidative Stress ELISA Strip (Colorimetric) (EA-1401)

Lange, J., Haslett, L. J., Lloyd-Evans, E., Pocock, J. M., Sands, M. S., Williams, B. P., & Cooper, J. D. (2018). Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis. Acta Neuropathological Communications, 6(1). https://doi.org/10.1186/s40478-018-0575-4

Cited in Research, Specific Product Unspecified

Azimzadeh, O., Sievert, W., Sarioglu, H., & Merl-Pham, J. (2015). Integrative proteomics and targeted transcriptomics analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular dysfunction. Journal of Proteome Research, 14(2), 1203–1219. https://doi.org/10.1021/pr501141b
Mohsin, S., Avitabile, D., & Khan, M. (2015). Stem cells and cardiac repair. Stem Cells International, 2015, Article ID 153627. https://doi.org/10.1155/2015/153627
Yeap, S. K., Abu, N., Mohamad, N. E., Beh, B. K., & Ho, W. Y. (2015). Chemopreventive and immunomodulatory effects of Murraya koenigii aqueous extract on 4T1 breast cancer cell-challenged mice. BMC Complementary and Alternative Medicine, 15, 306. https://doi.org/10.1186/s12906-015-0832-z
An, T. W., Kim, S. J., Lee, Y. D., Park, J. H., & Chang, H. (2014). The immune-enhancing effect of the Cronobacter sakazakii ES2 phage results in the activation of nuclear factor-κB and dendritic cell maturation via the activation of IL-12 p40 in the mouse bone marrow. Immunology Letters, 157(1-2), 1–8. https://doi.org/10.1016/j.imlet.2014.01.004
Wan, J., Lata, C., Santilli, A., Green, D., Roy, S., & Santilli, S. (2013). Supplemental oxygen reverses hypoxia-induced smooth muscle cell proliferation by modulating HIF-alpha and VEGF levels in a rabbit arteriovenous fistula model. Annals of Vascular Surgery. Advance online publication. https://doi.org/10.1016/j.avsg.2013.12.015
Kawachi, Y., Maruyama, H., Ishitsuka, Y., Fujisawa, Y., Furuta, J., Nakamura, Y., Ichikawa, E., Furumura, M., & Otsuka, F. (2013). NF1 gene silencing induces upregulation of VEGF expression in both Schwann and non-Schwann cells. Experimental Dermatology, 22(4), 262–265. https://doi.org/10.1111/exd.12115
Spano, D., Marshall, J.-C., Marino, N., De Martino, D., Romano, A., Scoppettuolo, M. N., Bello, A. M., Di Dato, V., Navas, L., De Vita, G., Medaglia, C., Steeg, P. S., & Zollo, M. (2013). Dipyridamole prevents triple-negative breast-cancer progression. Clinical & Experimental Metastasis, 30(1), 47–68. https://doi.org/10.1007/s10585-012-9506-0
Hiesinger, W., Perez-Aguilar, J. M., Atluri, P., Marotta, N. A., Frederick, J. R., Fitzpatrick, J. R., McCormick, R. C., Muenzer, J. R., Yang, E. C., Levit, R. D., Yuan, L. J., MacArthur, J. W., Saven, J. G., & Woo, Y. J. (2012). Computational protein design to reengineer stromal cell–derived factor-1α generates an effective and translatable angiogenic polypeptide analog. Circulation, 124(12 Suppl), S18–S26. https://doi.org/10.1161/CIRCULATIONAHA.111.045275
Shin, K. K., Lee, A. L., Kim, J. Y., Lee, S. Y., Bae, Y. C., & Jung, J. S. (2012). miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo. Biochemical and Biophysical Research Communications, 422(4), 633–638. https://doi.org/10.1016/j.bbrc.2012.05.130
Koeppen, M., Harter, P. N., Bonney, S., Bonney, M., Reithel, S., Zachskorn, C., Mittelbronn, M., & Eckle, T. (2012). Adora2b signaling on bone marrow derived cells dampens myocardial ischemia-reperfusion injury. Anesthesiology, 116(6), 1245–1257. https://doi.org/10.1097/ALN.0b013e318258b3f7
Yoshizuka, N., Chen, R. M., Xu, Z., Liao, R., Hong, L., Hu, W. Y., Yu, G., Han, J., Chen, L., & Sun, P. (2012). A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis. Molecular and Cellular Biology, 32(6), 606–618. https://doi.org/10.1128/MCB.06032-11
Blazer-Yost, B. L., Banga, A., Amos, A., Chernoff, E., Lai, X., Li, C., Mitra, S., & Witzmann, F. A. (2011). Effect of carbon nanoparticles on renal epithelial cell structure, barrier function, and protein expression. Nanotoxicology, 5(3), 354–371. https://doi.org/10.3109/17435390.2010.514076
Glaeser, J., Geissler, S., Ode, A., Schipp, C. J., Matziolis, G., Taylor, W. R., Knaus, P., Perka, C., Duda, G. N., & Kasper, G. (2010). Modulation of matrix metalloprotease-2 levels by mechanical loading of three-dimensional mesenchymal stem cell constructs: Impact on in vitro tube formation. Tissue Engineering Part A, 16(10), 3139–3148. https://doi.org/10.1089/ten.tea.2009.0695
Crouzier, D., Follot, S., Gentilhomme, E., Flahaut, E., Arnaud, R., Dabouis, V., Castellarin, C., & Debouzy, J. C. (2010). Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung. Toxicology, 272(1-3), 39–45. https://doi.org/10.1016/j.tox.2010.03.002

Rat Cytokine ELISA Strips

Rat Inflammation ELISA Strip (Chemiluminescence) (EA-1801)

Rathinavel, T., Ammashi, S., & Shanmugam, G. (2021). Analgesic and anti-inflammatory potential of lupeol isolated from Indian traditional medicinal plant Crateva adansonii screened through in vivo and in silico approaches. Journal of Genetic Engineering and Biotechnology, 19(1), 62. https://doi.org/10.1186/s43141-021-00167-6

Rat Angiogenesis ELISA Strip (Chemiluminescence) (EA-1811)

Majumder, K., Chakrabarti, S., Morton, J. S., Panahi, S., Kaufman, S., Davidge, S. T., & Wu, J. (2013). Egg-derived tri-peptide IRW exerts antihypertensive effects in spontaneously hypertensive rats. PLoS ONE, 8(11), e82829. https://doi.org/10.1371/journal.pone.0082829

Rat Inflammation ELISA Strip (Colorimetric) (EA-1201)

Reddy, S. K., Ballal, A. R., Shailaja, S., Seetharam, R. N., Raghu, C. H., Sankhe, R., Pai, K., Tender, T., Mathew, M., Aroor, A., Shetty, A. K., Adiga, S., Devi, V., Muttigi, M. S., & Upadhya, D. (2023). Small extracellular vesicle-loaded bevacizumab reduces the frequency of intravitreal injection required for diabetic retinopathy. Theranostics, 13(7), 2241–2255. https://doi.org/10.7150/thno.78426
Hogarth, K., Vanama, R. B., Stratmann, G., & others. (2021). Singular and short-term anesthesia exposure in the developing brain induces persistent neuronal changes consistent with chronic neurodegenerative disease. Scientific Reports, 11, 5673. https://doi.org/10.1038/s41598-021-85125-5
Rathinavel, T., Ammashi, S., & Shanmugam, G. (2021). Analgesic and anti-inflammatory potential of lupeol isolated from Indian traditional medicinal plant Crateva adansonii screened through in vivo and in silico approaches. Journal of Genetic Engineering and Biotechnology, 19(1), 62. https://doi.org/10.1186/s43141-021-00167-6
Tun, S. B. B., Barathi, V. A., Luu, C. D., & others. (2019). Effects of exogenous neuroglobin (Ngb) on retinal inflammatory chemokines and microglia in a rat model of transient hypoxia. Scientific Reports, 9, 18799. https://doi.org/10.1038/s41598-019-55315-3

Rat Angiogenesis ELISA Strip (Colorimetric) (EA-1211)

Majumder, K., Chakrabarti, S., Morton, J. S., Panahi, S., Kaufman, S., Davidge, S. T., & Wu, J. (2013). Egg-derived tri-peptide IRW exerts antihypertensive effects in spontaneously hypertensive rats. PLoS ONE, 8(11), e82829. https://doi.org/10.1371/journal.pone.0082829

Cited in Research, Specific Product Unspecified

Hong, W., Tang, L., Ge, R., et al. (2021). Persistent abnormal immunocytes induced systemic bone loss in locally irradiated rats. Calcified Tissue International. https://doi.org/10.1007/s00223-021-00883-8
Fan, X., Elkin, K., Shi, Y., Zhang, Z., Cheng, Y., Gu, J., Liang, J., Wang, C., & Ji, X. (2020). Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition. Neurological Research. https://doi.org/10.1080/01616412.2020.1782079
Boarescu, P.-M., et al. (2019). Effects of curcumin nanoparticles in isoproterenol-induced myocardial infarction. Oxidative Medicine and Cellular Longevity, 2019, 1–13. https://doi.org/10.1155/2019/7847142
Chen, Y.-C., Ho, C.-C., Yi, C.-H., Liu, X.-Z., Cheng, T.-T., & Lam, C.-F. (2017). Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. PLoS ONE, 12(11), Article e0187434. https://doi.org/10.1371/journal.pone.0187434
Armstead, A. L., Minarchick, V. C., Porter, D. W., et al. (2015). Acute inflammatory responses of nanoparticles in an intra-tracheal instillation rat model. PLoS ONE, 10(3), Article e0118778. https://doi.org/10.1371/journal.pone.0118778
Sakata, S., Hanaoka, T., Ishizawa, R., Iwami, K., & Takada, Y. (2015). Poor wheel-running exercise can decrease blood pressure through hormonal control and increase endurance exercise capacity in middle-aged normal rats. Journal of Biosciences and Medicines, 3, 10–24. https://doi.org/10.4236/jbm.2015.33002
Merino-Aguilar, H., Arrieta-Baez, D., Jiménez-Estrada, M., Magos-Guerrero, G., Hernández-Bautista, R. J., Susunaga-Notario, A. C., Almanza-Pérez, J. C., Blancas-Flores, G., Román-Ramos, R., & Alarcón-Aguilar, F. J. (2014). Effect of fructooligosaccharides fraction from Psacalium decompositum on inflammation and dyslipidemia in rats with fructose-induced obesity. Nutrients, 6(2), 591–604. https://doi.org/10.3390/nu6020591
Yadav, V. R., Sahoo, K., Roberts, P. R., & Awasthi, V. (2013). Pharmacologic suppression of inflammation by a diphenyldifluoroketone, EF24, in a rat model of fixed-volume hemorrhage improves survival. Journal of Pharmacology and Experimental Therapeutics. Advance online publication. https://doi.org/10.1124/jpet.113.206378
Valladares, R., Bojilova, L., Potts, A. H., Cameron, E., Gardner, C., Lorca, G., & Gonzalez, C. F. (2013). Lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in BioBreeding rats. FASEB Journal, 27(4), 1711–1720. https://doi.org/10.1096/fj.12-223973
Sun, Y. W., Guttenplan, J. B., Cooper, T., Krzeminski, J., Aliaga, C., Boyiri, T., Kosinska, W., Zhao, Z. L., Chen, K. M., Berg, A., Amin, S. G., & El-Bayoumy, K. (2013). Mechanisms underlying the varied mammary carcinogenicity of the environmental pollutant 6-nitrochrysene and its metabolites (-)-[R,R]- and (+)-[S,S]-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene in the rat. Chemical Research in Toxicology. Advance online publication. https://doi.org/10.1021/tx400020n
Nasrin, S., Masuda, E., Kugaya, H., Ito, Y., & Yamada, S. (2013). Effects of saw palmetto extract on urodynamic parameters, bladder muscarinic and purinergic receptors, and urinary cytokines in rats with cyclophosphamide. Journal of Urology, 189(3), 1123–1129. https://doi.org/10.1016/j.juro.2012.09.054
Nasrin, S., Masuda, E., Kugaya, H., Ito, Y., & Yamada, S. (2013). Improvement by the phytotherapeutic agent Eviprostat of detrusor overactivity, downregulation of pharmacological receptors, and urinary cytokines in rats with cyclophosphamide-induced cystitis. Journal of Urology, 189(3), 1123–1129. https://doi.org/10.1016/j.juro.2012.09.054
Moyer-Mileur, L. J., Haley, S., Slater, H., Beachy, J., & Smith, S. L. (2012). Massage improves growth quality by decreasing body fat deposition in male preterm infants. Journal of Pediatrics, 161(4), 540–545. https://doi.org/10.1016/j.jpeds.2012.03.047
(2012). Chemopreventive efficacy of hesperetin (citrus flavonone) against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Toxicology Mechanisms and Methods, 22(5), 397–408. https://doi.org/10.3109/15376516.2012.674245
Forrest, C. M., Khalil, O. S., Pisar, M., Smith, R. A., Darlington, L. G., & Stone, T. W. (2012). Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I
) changes synaptic proteins, N-methyl-D-aspartate receptors, and neurogenesis markers in offspring. Molecular Brain, 5(1), 22. https://doi.org/10.1186/1756-6606-5-22
Burgess, A. P., Vanella, L., Bellner, L., Gotlinger, K., Falck, J. R., Abraham, N. G., Schwartzman, M. L., & Kappas, A. (2012). Heme oxygenase (HO-1) rescue of adipocyte dysfunction in HO-2 deficient mice via recruitment of epoxyeicosatrienoic acids (EETs) and adiponectin. Cell Physiology and Biochemistry, 29(1-2), 99–110. https://doi.org/10.1159/000336120
Luo, N., Liu, J., Chung, B. H., Yang, Q., Klein, R. L., Garvey, W. T., & Fu, Y. (2010). Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis. Diabetes, 59(4), 791–799. https://doi.org/10.2337/db09-0515

Human Cytokine ELISA Kits

Human TNFα ELISA (EA-0203)

Rahardjo, B., Widjajanto, E., Sujuti, H., & Keman, K. (2014). Curcumin decreased level of proinflammatory cytokines in monocyte cultures exposed to preeclamptic plasma by affecting the transcription factors NF-κB and PPAR-γ. Biomarkers and Genomic Medicine, 6(3), 105–115. https://doi.org/10.1016/j.bgm.2014.06.002
Alcendor, D. J., Charest, A. M., Zhu, W. Q., Vigil, H. E., & Knobel, S. M. (2012). Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus. Journal of Neuroinflammation, 9(1), 95. https://doi.org/10.1186/1742-2094-9-95

Human Resistin ELISA (EA-0205)

Deshmukh, S. K., Srivastava, S. K., Bhardwaj, A., Singh, A. P., Tyagi, N., Marimuthu, S., Dyess, D. L., Zotto, V. D., Carter, J. E., & Singh, S. (2015). Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation. Oncotarget, 6(13), 11231–11241. https://doi.org/10.18632/oncotarget.3591

Human IL-6 ELISA (EA-0206)

Deshmukh, S. K., Srivastava, S. K., Bhardwaj, A., Singh, A. P., Tyagi, N., Marimuthu, S., Dyess, D. L., Zotto, V. D., Carter, J. E., & Singh, S. (2015). Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation. Oncotarget, 6(13), 11231–11241. https://doi.org/10.18632/oncotarget.3591
Rahardjo, B., Widjajanto, E., Sujuti, H., & Keman, K. (2014). Curcumin decreased level of proinflammatory cytokines in monocyte cultures exposed to preeclamptic plasma by affecting the transcription factors NF-κB and PPAR-γ. Biomarkers and Genomic Medicine, 6(3), 105–115. https://doi.org/10.1016/j.bgm.2014.06.002
Alcendor, D. J., Charest, A. M., Zhu, W. Q., Vigil, H. E., & Knobel, S. M. (2012). Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus. Journal of Neuroinflammation, 9(1). https://doi.org/10.1186/1742-2094-9-95

Human PDGF-BB ELISA (EA-0404)

Xiao, F., Liu, X., & Guo, S.-W. (2022). Interleukin-33 derived from endometriotic lesions promotes fibrogenesis through inducing the production of profibrotic cytokines by regulatory T cells. Biomedicines, 10(11), 2893. https://doi.org/10.3390/biomedicines10112893

Human IL-1α ELISA (EA-0503)

Rahardjo, B., Widjajanto, E., Sujuti, H., & Keman, K. (2014). Curcumin decreased level of proinflammatory cytokines in monocyte cultures exposed to preeclamptic plasma by affecting the transcription factors NF-κB and PPAR-γ. Biomarkers and Genomic Medicine, 6(3), 105–115. https://doi.org/10.1016/j.bgm.2014.06.002

Cited in Research, Specific Product Unspecified

Kamath, M. G., Pai, C. G., Kamath, A., & Kurien, A. (2016). Monocyte chemoattractant protein-1, transforming growth factor-beta1, nerve growth factor, resistin and hyaluronic acid as serum markers: Comparison between recurrent acute and chronic pancreatitis. Hepatobiliary & Pancreatic Diseases International, 15(2), 209–215. https://doi.org/10.1016/s1499-3872(15)60029-7
Camaré, C., Trayssac, M., Garmy-Susini, B., & Mucher, E. (2014). Oxidized LDL-induced angiogenesis involves sphingosine-1-phosphate: Prevention by anti-S1P antibody. British Journal of Pharmacology, 172(1), 106–118. https://doi.org/10.1111/bph.12306
Wang, Y. W., & Kuo, C. F. (2014). 2,4,5-Trimethoxybenzaldehyde, a bitter principle in plants, suppresses adipogenesis through the regulation of ERK1. Journal of Agricultural and Food Chemistry, 62(40), 9860–9867. https://doi.org/10.1021/jf503344v
Rosser, C. J., Ross, S., Chang, M., Dai, Y., Mengual, L., Zhang, G., Kim, J., Urquidi, V., Alcaraz, A., & Goodison, S. (2013). Multiplex protein signature for the detection of bladder cancer in voided urine samples. Journal of Urology. Advance online publication. https://doi.org/10.1016/j.juro.2013.03.067
Morcos, N. Y., Zakhary, N. I., Said, M. M., & Tadros, M. M. (2013). Postoperative simple biochemical markers for prediction of bone metastases in Egyptian breast cancer patients. ecancermedicalscience, 7, 305. https://doi.org/10.3332/ecancer.2013.305
Tymen, S. D., Rojas, I. G., Zhou, X., Fang, Z. J., Zhao, Y., & Marucha, P. T. (2013). Restraint stress alters neutrophil and macrophage phenotypes during wound healing. Brain, Behavior, and Immunity, 28, 207–217. https://doi.org/10.1016/j.bbi.2012.07.013
Yang, Z., Chevolot, Y., Ataman-Önal, Y., Choquet-Kastylevsky, G., Souteyrand, E., & Laurenceau, E. (2012). Cancer biomarkers detection using 3D microstructured protein chip: Implementation of customized multiplex immunoassay. Sensors and Actuators B: Chemical, 175, 22–28. https://doi.org/10.1016/j.snb.2012.07.014
Goodison, S., Chang, M., Dai, Y., Urquidi, V., & Rosser, C. J. (2012). A multi-analyte assay for the non-invasive detection of bladder cancer. PLoS ONE, 7(10), Article e47469. https://doi.org/10.1371/journal.pone.0047469
Uzhachenko, R., Issaeva, N., Boyd, K., Ivanov, S. V., Carbone, D. P., & Ivanova, A. V. (2012). Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis. Journal of Pathology, 227(4), 456–469. https://doi.org/10.1002/path.4072
Feng, X., Scheinberg, P., Samsel, L., Rios, O., Chen, J., McCoy, J. P. Jr., Ghanima, W., Bussel, J. B., & Young, N. S. (2012). Decreased plasma cytokines associate with low platelet counts in aplastic anemia and immune thrombocytopenic purpura. Journal of Thrombosis and Haemostasis, 10(8), 1616–1623. https://doi.org/10.1111/j.1538-7836.2012.04829.x
Yao, H. W., Chen, S. H., Li, C., Tung, Y. Y., & Chen, S. H. (2012). Suppression of transcription factor early growth response 1 reduces herpes simplex virus type I-induced corneal disease in mice. Journal of Virology, 86(16), 8559–8567. https://doi.org/10.1128/JVI.00505-12
Weltrowski, A., da Silva Almeida, M. L., Peschel, D., Zhang, K., Fischer, S., & Groth, T. (2012). Mitogenic activity of sulfated chitosan and cellulose derivatives is related to protection of FGF-2 from proteolytic cleavage. Macromolecular Bioscience, 12(6), 740–750. https://doi.org/10.1002/mabi.201200033
Herranz-López, M., Fernández-Arroyo, S., Pérez-Sanchez, A., Barrajón-Catalán, E., Beltrán-Debón, R., Menéndez, J. A., Alonso-Villaverde, C., Segura-Carretero, A., Joven, J., & Micol, V. (2012). Synergism of plant-derived polyphenols in adipogenesis: Perspectives and implications. Phytomedicine, 19(3-4), 253–261. https://doi.org/10.1016/j.phymed.2011.12.001
Garg, M. K., Dutta, M. K., & Mahalle, N. (2012). Adipokines (adiponectin and plasminogen activator inhibitor-1) in metabolic syndrome. Indian Journal of Endocrinology and Metabolism, 16(1), 116–123. https://doi.org/10.4103/2230-8210.94050
Urquidi, V., Kim, J., Chang, M., Dai, Y., Rosser, C. J., & Goodison, S. (2012). CCL18 in a multiplex urine-based assay for the detection of bladder cancer. PLoS ONE, 7(5), Article e37797. https://doi.org/10.1371/journal.pone.0037797
Chen, C. P., Tai, D. W., Chen, W. J., & Lai, H. M. (2012). The effect of e-learning on the promotion of optoelectronics technology and daily living literacy among students in universities of technology. World Academy of Science, Engineering and Technology, 65, 439–443.
Wang, J., & Yau, S. T. (2011). Field-effect amperometric immuno-detection of protein biomarker. Biosensors and Bioelectronics, 29(1), 210–214. https://doi.org/10.1016/j.bios.2011.07.012
Kook, S. H., Jang, Y. S., & Lee, J. C. (2011). Human periodontal ligament fibroblasts stimulate osteoclastogenesis in response to compression force through TNF-α-mediated activation of CD4+ T cells. Journal of Cellular Biochemistry, 112(10), 2891–2901. https://doi.org/10.1002/jcb.23221
Dai, Y., Chen, S., Shah, R., Pei, X. Y., Wang, L., Almenara, J. A., Kramer, L. B., Dent, P., & Grant, S. (2011). Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo. Blood, 117(6), 1947–1957. https://doi.org/10.1182/blood-2010-06-291146
Basati, G., Pourfarzam, M., Movahedian, A., Samsamshariat, S. Z., & Sarrafzadegan, N. (2011). Reduced plasma adiponectin levels relative to oxidized low density lipoprotein and nitric oxide in coronary artery disease patients. Clinics (São Paulo), 66(7), 1129–1135. https://doi.org/10.6061/clinics/2011(07)07
Perreault, L., Bergman, B. C., Hunerdosse, D. M., & Eckel, R. H. (2010). Altered intramuscular lipid metabolism relates to diminished insulin action in men, but not women, in progression to diabetes. Obesity (Silver Spring), 18(11), 2093–2100. https://doi.org/10.1038/oby.2010.196
Lan, W. J., Hao, G. K., Wang, J., Zhang, R. H., Lan, W., Wang, R. M., Sun, R., & Wang, T. F. (2010). Duplexed on-microbead binding assay for competitive inhibitor of epidermal growth factor receptor by quantitative flow cytometry. Basic & Clinical Pharmacology & Toxicology, 107(1), 560–564. https://doi.org/10.1111/j.1742-7843.2010.00570.x
Washburn, A. L., Gunn, L. C., & Bailey, R. C. (2009). Label-free quantitation of a cancer biomarker in complex media using silicon photonic microring resonators. Analytical Chemistry, 81(22), 9499–9506. https://doi.org/10.1021/ac902050u

Mouse Cytokine ELISA Kits

Mouse IL-6 ELISA (EA-2206)

Joshi, J. C., Joshi, B., Rochford, I., Rayees, S., Akhter, M. Z., Baweja, S., Chava, K. R., Tauseef, M., Abdelkarim, H., Natarajan, V., Gaponenko, V., & Mehta, D. (2020). SPHK2-generated S1P in CD11B+ macrophages blocks STING to suppress the inflammatory function of alveolar macrophages. Cell Reports, 30(12), 3907–3921. https://doi.org/10.1016/j.celrep.2020.02.112
Carret-Rebillat, A.-S., Pace, C., Gourmaud, S., Ravasi, L., Montagne-Stora, S., Longueville, S., Tible, M., Sudol, E., Chang, R. C.-C., Paquet, C., Mouton-Liger, F., & Hugon, J. (2015). Neuroinflammation and Aβ accumulation linked to systemic inflammation are decreased by genetic PKR down-regulation. Scientific Reports, 5(1), 8489. https://doi.org/10.1038/srep08489
Sasi, S. P., Song, J., Park, D., Enderling, H., McDonald, J. T., Gee, H., Garrity, B., Shtifman, A., Yan, X., Walsh, K., Natarajan, M., Kishore, R., & Goukassian, D. A. (2014). TNF-TNFR2/P75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. Journal of Biological Chemistry, 289(20), 14178–14193. https://doi.org/10.1074/jbc.m114.567743

Mouse MCP-1 ELISA (EA-2408)

Sasi, S. P., Song, J., Park, D., Enderling, H., McDonald, J. T., Gee, H., Garrity, B., Shtifman, A., Yan, X., Walsh, K., Natarajan, M., Kishore, R., & Goukassian, D. A. (2014). TNF-TNFR2/P75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. Journal of Biological Chemistry, 289(20), 14178–14193. https://doi.org/10.1074/jbc.m114.567743

Mouse MIP-1α ELISA (EA-2409)

Sasi, S. P., Song, J., Park, D., Enderling, H., McDonald, J. T., Gee, H., Garrity, B., Shtifman, A., Yan, X., Walsh, K., Natarajan, M., Kishore, R., & Goukassian, D. A. (2014). TNF-TNFR2/P75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. Journal of Biological Chemistry, 289(20), 14178–14193. https://doi.org/10.1074/jbc.m114.567743

Mouse IL-1α ELISA (EA-2503)

Sasi, S. P., Song, J., Park, D., Enderling, H., McDonald, J. T., Gee, H., Garrity, B., Shtifman, A., Yan, X., Walsh, K., Natarajan, M., Kishore, R., & Goukassian, D. A. (2014). TNF-TNFR2/P75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. Journal of Biological Chemistry, 289(20), 14178–14193. https://doi.org/10.1074/jbc.m114.567743

Mouse Rantes ELISA (EA-2506)

Sasi, S. P., Song, J., Park, D., Enderling, H., McDonald, J. T., Gee, H., Garrity, B., Shtifman, A., Yan, X., Walsh, K., Natarajan, M., Kishore, R., & Goukassian, D. A. (2014). TNF-TNFR2/P75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. Journal of Biological Chemistry, 289(20), 14178–14193. https://doi.org/10.1074/jbc.m114.567743

Mouse IL-1β ELISA (EA-2508)

Joshi, J. C., Joshi, B., Rochford, I., Rayees, S., Akhter, M. Z., Baweja, S., Chava, K. R., Tauseef, M., Abdelkarim, H., Natarajan, V., Gaponenko, V., & Mehta, D. (2020). SPHK2-generated S1P in CD11B+ macrophages blocks STING to suppress the inflammatory function of alveolar macrophages. Cell Reports, 30(12), 3851–3864. https://doi.org/10.1016/j.celrep.2020.02.112
Sasi, S. P., Song, J., Park, D., Enderling, H., McDonald, J. T., Gee, H., Garrity, B., Shtifman, A., Yan, X., Walsh, K., Natarajan, M., Kishore, R., & Goukassian, D. A. (2014). TNF-TNFR2/P75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. Journal of Biological Chemistry, 289(20), 14178–14193. https://doi.org/10.1074/jbc.m114.567743

Cited in Research, Specific Product Unspecified

Feng, X., Scheinberg, P., Samsel, L., Rios, O., Chen, J., McCoy, J. P. Jr., Ghanima, W., Bussel, J. B., & Young, N. S. (2012). Decreased plasma cytokines associate with low platelet counts in aplastic anemia and immune thrombocytopenic purpura. Journal of Thrombosis and Haemostasis, 10(8), 1616–1623. https://doi.org/10.1111/j.1538-7836.2012.04706.x
Matthews, J. A., Sala, F. G., Speer, A. L., Li, Y., Warburton, D., & Grikscheit, T. C. (2012). Mesenchymal-specific inhibition of vascular endothelial growth factor (VEGF) attenuates growth in neonatal mice. Journal of Surgical Research, 172(1), 40–47. https://doi.org/10.1016/j.jss.2011.04.043
Matthews, J. A., Sala, F. G., Speer, A. L., Warburton, D., & Grikscheit, T. C. (2011). VEGF optimizes the formation of tissue-engineered small intestine. Regenerative Medicine, 6(5), 559–567. https://doi.org/10.2217/rme.11.38

Rat Cytokine ELISA Kits

Rat TNFα ELISA (EA-3001)

Reddy, S. K., Ballal, A. R., Shailaja, S., Seetharam, R. N., Raghu, C. H., Sankhe, R., Pai, K., Tender, T., Mathew, M., Aroor, A., Shetty, A. K., Adiga, S., Devi, V., Muttigi, M. S., & Upadhya, D. (2023). Small extracellular vesicle-loaded bevacizumab reduces the frequency of intravitreal injection required for diabetic retinopathy. Theranostics, 13(7), 2241–2255. https://doi.org/10.7150/thno.78426

Rat IL-6 ELISA (EA-3002)

Chen, Y.-C., Ho, C.-C., Yi, C.-H., Liu, X.-Z., Cheng, T.-T., & Lam, C.-F. (2017). Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. PLOS ONE, 12(11), Article e0187434. https://doi.org/10.1371/journal.pone.0187434

Rat IL-1β ELISA (EA-3005)

Reddy, S. K., Ballal, A. R., Shailaja, S., Seetharam, R. N., Raghu, C. H., Sankhe, R., Pai, K., Tender, T., Mathew, M., Aroor, A., Shetty, A. K., Adiga, S., Devi, V., Muttigi, M. S., & Upadhya, D. (2023). Small extracellular vesicle-loaded bevacizumab reduces the frequency of intravitreal injection required for diabetic retinopathy. Theranostics, 13(7), 2241–2255. https://doi.org/10.7150/thno.78426
Chen, Y.-C., Ho, C.-C., Yi, C.-H., Liu, X.-Z., Cheng, T.-T., & Lam, C.-F. (2017). Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. PLOS ONE, 12(11), Article e0187434. https://doi.org/10.1371/journal.pone.0187434

Rat MCP-1 ELISA (EA-3006)

Chen, Y.-C., Ho, C.-C., Yi, C.-H., Liu, X.-Z., Cheng, T.-T., & Lam, C.-F. (2017). Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. PLOS ONE, 12(11), Article e0187434. https://doi.org/10.1371/journal.pone.0187434

Rat IP-10 ELISA (EA-3012)

Chen, Y.-C., Ho, C.-C., Yi, C.-H., Liu, X.-Z., Cheng, T.-T., & Lam, C.-F. (2017). Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. PLOS ONE, 12(11), Article e0187434. https://doi.org/10.1371/journal.pone.0187434

Cited in Research, Specific Product Unspecified

Dogaru, G., Tache, D., Pitea, D., & Dima, M. (2020). Effect of liposomal curcumin on acetaminophen hepatotoxicity by down-regulation of oxidative stress and matrix metalloproteinases. In Vivo, 34(2), 569–582. https://doi.org/10.21873/invivo.11809
Schuchman, E. H., Ge, Y., Lai, A., Borisov, Y., Faillace, M., Eliyahu, E., He, X., Iatridis, J., Vlassara, H., Striker, G., & Simonaro, C. M. (2013). Pentosan polysulfate: A novel therapy for the mucopolysaccharidoses. PLoS ONE, 8(1), Article e54459. https://doi.org/10.1371/journal.pone.0054459
Mukherjee, S., Katki, K., Arisi, G. M., Foresti, M. L., & Shapiro, L. A. (2011). Early TBI-induced cytokine alterations are similarly detected by two distinct methods of multiplex assay. Frontiers in Molecular Neuroscience, 4, 21. https://doi.org/10.3389/fnmol.2011.00021

miRNA Research

miRNA Northern Blot Assays

miRNA Northern Blot Assay without gels

Ye, J., Zhang, X., Tan, J., Xu, F., Cheng, S., Chen, Z., Zhang, W., & Liao, Y. (2020). Global identification of Ginkgo Biloba microRNAs and insight into their role in the metabolism regulatory network of terpene trilactones by high-throughput sequencing and degradome analysis. Industrial Crops and Products, 148, 112289. https://doi.org/10.1016/j.indcrop.2020.112289
Xu, Y., Zalzala, M., Xu, J., Li, Y., Yin, L., & Zhang, Y. (2015). A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism. Nature Communications, 6, 7466. https://doi.org/10.1038/ncomms8466
Yang, Q., Li, W., She, H., Dou, J., Duong, D. M., Du, Y., ... & Wang, S. (2015). Stress induces p38 MAPK-mediated phosphorylation and inhibition of Drosha-dependent cell survival. Molecular Cell, 57(1), 184-196. https://doi.org/10.1016/j.molcel.2015.01.007
McClure, C., Ali, E., Youssef, D., Yao, Z. Q., & McCall, C. E. (2015). NFI-A disrupts myeloid cell differentiation and maturation in septic mice. Journal of Leukocyte Biology, Published online before print. https://doi.org/10.1189/jlb.4A0415-171RR
Ma, X., Xin, Z., Wang, Z., Yang, Q., Guo, S., Guo, X., ... & Cao, L. (2015). Identification and comparative analysis of differentially expressed miRNAs in leaves of two wheat (Triticum aestivum L.) genotypes during dehydration stress. BMC Plant Biology, 15(1), 134. https://doi.org/10.1186/s12870-015-0528-9
Salvi, A., Sabelli, C., Moncini, S., Venturin, M., Arici, B., Riva, P., ... & Barlati, S. (2009). MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells. The FEBS Journal, 276(11), 2950-2964. https://doi.org/10.1111/j.1742-4658.2009.07014.x
Rajendiran, S., Parwani, A. V., Hare, R. J., & Dasgupta, S. (2014). MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1. Molecular Cancer, 13, 166. https://doi.org/10.1186/1476-4598-13-166
Chen, J., Zhang, X., Lentz, C., Abi-Daoud, M., Paré, G. C., Yang, X., Feilotter, H. E., & Tron, V. A. (2011). MiR-193b regulates MCL-1 in melanoma. The American Journal of Pathology, 179(5), 2162-2168. https://doi.org/10.1016/j.ajpath.2011.07.010
Chen, K. C., Hsieh, I. C., Hsi, E., Wang, Y. S., Dai, C. Y., Chou, W. W., & Juo, S. H. (2011). Negative feedback regulation between microRNA let-7g and the oxLDL receptor LOX-1. Journal of Cell Science, 124(Pt 23), 4115-4124. https://doi.org/10.1242/jcs.086348
Ruebel, K., Leontovich, A. A., Stilling, G. A., Zhang, S., Righi, A., Jin, L., & Lloyd, R. V. (2010). MicroRNA expression in ileal carcinoid tumors: Downregulation of microRNA-133a with tumor progression. Modern Pathology, 23(3), 367-375. https://doi.org/10.1038/modpathol.2009.161
Zhao, J., Cao, Y., Lei, Z., Yang, Z., Zhang, B., & Huang, B. (2010). Selective depletion of CD4+CD25+Foxp3+ regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels. Cancer Research, 70(12), 4850-4858. https://doi.org/10.1158/0008-5472.CAN-09-4068
Liu, Z., Xiao, B., Tang, B., Li, B., Li, N., Zhu, E., Guo, G., Gu, J., Zhuang, Y., Liu, X., Ding, H., Zhao, X., Guo, H., Mao, X., & Zou, Q. (2010). Up-regulated microRNA-146a negatively modulates Helicobacter pylori-induced inflammatory response in human gastric epithelial cells. Microbes and Infection, 12(11), 854-863. https://doi.org/10.1016/j.micinf.2010.06.002
Sugatani, T., & Hruska, K. A. (2009). Impaired micro-RNA pathways diminish osteoclast differentiation and function. Journal of Biological Chemistry, 284(7), 4667-4678. https://doi.org/10.1074/jbc.m805777200
Wang, Q., Ji, X., Gao, Y., Qi, X., Wang, X., Wang, Y., Qin, L., Gao, H., & Wang, X. (2013). Overexpression of microRNA gga-mir-1650 decreases the replication of avian leukosis virus subgroup J in infected cells. Journal of General Virology, 94(10), 2287-2296. https://doi.org/10.1099/vir.0.054007-0
Viñas, J. L., Ventayol, M., Brüne, B., Jung, M., Sola, A., Pi, F., Mastora, C., & Hotter, G. (2013). miRNA let-7e modulates the Wnt pathway and early nephrogenic markers in mouse embryonic stem cell differentiation. PLoS ONE, 8(4), e60937. https://doi.org/10.1371/journal.pone.0060937
Meng, F., Glaser, S. S., Francis, H., DeMorrow, S., Han, Y., Passarini, J. D., ... & Alpini, G. (2012). Functional analysis of microRNAs in human hepatocellular cancer stem cells. Journal of Cellular and Molecular Medicine, 16(1), 160-173. https://doi.org/10.1111/j.1582-4934.2011.01321.x
Chen, K. C., Liao, Y. C., Hsieh, I. C., Wang, Y. S., Hu, C. Y., & Juo, S. H. (2012). OxLDL causes both epigenetic modification and signaling regulation on the microRNA-29b gene: Novel mechanisms for cardiovascular diseases. Journal of Molecular and Cellular Cardiology, 52(3), 587-595. https://doi.org/10.1016/j.yjmcc.2011.10.015
Shi, M., Du, L., Liu, D., Qian, L., Hu, M., Yu, M., Yang, Z., Zhao, M., Chen, C., Guo, L., Wang, L., Song, L., Ma, Y., & Guo, N. (2012). Glucocorticoid regulation of a novel HPV–E6–p53–miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. The Journal of Pathology, 228(2), 148-157. https://doi.org/10.1002/path.3997
Zhang, T., Cheng, T., Wei, L., Cai, Y., Yeo, A. E., Han, J., Yuan, Y. A., & Zhang, J. (2012). Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct. Virology Journal, 9, 118. https://doi.org/10.1186/1743-422X-9-118
La Rocca, G., Shi, B., Sepp-Lorenzino, L., & Baserga, R. (2011). Expression of micro-RNA-145 is regulated by a highly conserved genomic sequence 3′ to the pre-miR. Journal of Cellular Physiology, 226(3), 602-607. https://doi.org/10.1002/jcp.22359
Rastogi, N., Gara, R. K., Trivedi, R., Singh, A., Dixit, P., Maurya, R., Duggal, S., Bhatt, M. L., & Mishra, D. P. (2014). Gingerol-induced myeloid leukemia cell death is initiated by reactive oxygen species and activation of miR-27b expression. Free Radical Biology and Medicine, 68, 288-301. https://doi.org/10.1016/j.freeradbiomed.2013.12.027
Chen, Y., Meng, L., Yu, Q., Dong, D., Tan, G., Huang, X., & Tan, Y. (2014). The miR-134 attenuates the expression of transcription factor FOXM1 during pluripotent NT2/D1 embryonal carcinoma cell differentiation. Experimental Cell Research, 326(2), 282-291. https://doi.org/10.1016/j.yexcr.2014.05.002
Yang, X., Liao, B., Liu, Z., Xie, W., Wang, Z., Huang, X., ... & Li, J. (2010). MicroRNA-23a targets PUMA and promotes cell survival in human osteosarcoma cells. Cancer Research, 70(1), 170-177. https://doi.org/10.1158/0008-5472.CAN-09-3485

Highly Sensitive miRNA Northern Blot Assay without gels

El Fatimy, R., Zhang, Y., Deforzh, E., et al. (2022). A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing. Molecular Cancer, 21(17). https://doi.org/10.1186/s12943-022-01494-z
Blumental-Perry, A., Jobava, R., Bederman, I., et al. (2020). Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics. Communications Biology, 3(626). https://doi.org/10.1038/s42003-020-01322-4
Qi, Y., et al. (2019). Latency-associated nuclear antigen inhibits lytic replication of Kaposi's sarcoma-associated herpesvirus by regulating let-7a/RBPJ signaling. Virology. https://doi.org/10.1016/j.virol.2019.02.019
Yang, Q., Li, W., She, H., Dou, J., Duong, D. M., Du, Y., Yang, S.-H., Seyfried, N. T., Fu, H., Gao, G., & Mao, Z. (2015). Stress induces p38 MAPK-mediated phosphorylation and inhibition of drosha-dependent cell survival. Molecular Cell, 57(4), 721–734. https://doi.org/10.1016/j.molcel.2015.01.004
Li, H., Dong, Y., Yin, H., et al. (2011). Characterization of the stress-associated microRNAs in Glycine max by deep sequencing. BMC Plant Biology, 11(170). https://doi.org/10.1186/1471-2229-11-170
Thai, T. H., Patterson, H. C., Pham, D. H., Kis-Toth, K., Kaminski, D. A., & Tsokos, G. C. (2013). Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse. Proceedings of the National Academy of Sciences, 110(50), 20194-20199. https://doi.org/10.1073/pnas.1316796110
Nageshbabu, R., Jyothi, M. N., Sharadamma, N., Sahu, S., Rai, D. V., & Devaraj, V. R. (2013). Expression of miRNAs regulates Growth and Development of French bean (Phaseolus vulgaris) under Salt and Drought Stress conditions. International Research Journal of Biological Sciences, 2(1), 52-56.

miRNA Luciferase Reporter Vectors

Landry, D. A., Sormany, F., Haché, J., Roumaud, P., & Martin, L. J. (2017). Steroidogenic genes expressions are repressed by high levels of leptin and the JAK/STAT signaling pathway in MA-10 Leydig cells. Molecular and Cellular Biochemistry. https://doi.org/10.1007/s11010-017-3017-x
Yang, Z., et al. (2017). Dicer reprograms stromal fibroblasts to a pro-inflammatory and tumor-promoting phenotype in ovarian cancer. Cancer Letters. https://doi.org/10.1016/j.canlet.2017.11.026
D'Ippolito, E., Plantamura, I., Bongiovanni, L., Casalini, P., Baroni, S., Piovan, C., ... & Tripodo, C. (2016). miR-9 and miR-200 regulate PDGFRβ-mediated endothelial differentiation of tumor cells in triple-negative breast cancer. Cancer Research, 76(18), 5562-5572. https://doi.org/10.1158/0008-5472.CAN-16-0140
Bretschneider, M., Busch, B., Mueller, D., & Nolze, A. (2016). Activated mineralocorticoid receptor regulates micro-RNA-29b in vascular smooth muscle cells. The FASEB Journal. https://doi.org/10.1096/fj.15-271254
Zhang, Y., Buhrman, J. S., Liu, Y., Rayahin, J. E., & Gemeinhart, R. A. (2016). Reducible micelleplexes are stable systems for anti-miRNA delivery in cerebrospinal fluid. Molecular Pharmaceutics. https://doi.org/10.1021/acs.molpharmaceut.5b00933
Srivastava, S. K., Bhardwaj, A., Arora, S., Tyagi, N., Singh, S., Andrews, J., McClellan, S., Wang, B., & Singh, A. P. (2015). MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways. British Journal of Cancer, 113(11), 660-668. https://doi.org/10.1038/bjc.2015.252
Hennemeier, I., Humpf, H. U., Gekle, M., & Schwerdt, G. (2014). Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells. Toxicology, 324, 116-122. https://doi.org/10.1016/j.tox.2014.07.012
Tsai, P. C., Bake, S., Balaraman, S., & Rawlings, J. (2014). MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells. Biology Open. https://doi.org/10.1242/bio.20147765
Gordillo, G. M., Biswas, A., Khanna, S., Pan, X., Sinha, M., Roy, S., & Sen, C. K. (2014). Dicer knockdown inhibits endothelial cell tumor growth via microRNA 21a-3p targeting of Nox-4. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.M113.524920
Kim, J. H., Park, S. G., Song, S. Y., Kim, J. K., & Sung, J. H. (2013). Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2. Cell Death & Disease, 4(4), e588. https://doi.org/10.1038/cddis.2013.105
Bao, B., Ahmad, A., Kong, D., Ali, S., Azmi, A. S., Li, Y., Banerjee, S., Padhye, S., & Sarkar, F. H. (2012). Hypoxia-induced aggressiveness of prostate cancer cells is linked with deregulated expression of VEGF, IL-6 and miRNAs that are attenuated by CDF. PLoS ONE, 7(8), e43726. https://doi.org/10.1371/journal.pone.0043726
Pan, Q., Ramakrishnaiah, V., Henry, S., Fouraschen, S., de Ruiter, P. E., Kwekkeboom, J., ... & van der Laan, L. J. W. (2012). Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi). Gut, 61(9), 1330-1339. https://doi.org/10.1136/gutjnl-2011-301705
Chan, Y. C., Roy, S., Huang, Y., Khanna, S., & Sen, C. K. (2012). The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by de-repressing the v-ets erythroblastosis virus E26 oncogene homolog 1 -matrix metalloproteinase-1 pathway. Journal of Biological Chemistry, 287(49), 41032-41043. https://doi.org/10.1074/jbc.M112.413294
Chan, Y. C., Khanna, S., Roy, S., & Sen, C. K. (2011). miR-200b targets Ets-1 and is down-regulated by hypoxia to induce angiogenic response of endothelial cells. Journal of Biological Chemistry, 286(3), 2047-2056. https://doi.org/10.1074/jbc.M110.169342
Chang, J. R., Mukerjee, R., Bagashev, A., Del Valle, L., Chabrashvili, T., Hawkins, B. J., He, J. J., & Sawaya, B. E. (2011). HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs. Journal of Biological Chemistry, 286(47), 41125-41134. https://doi.org/10.1074/jbc.M111.279315
Wang, X. H., Hu, Z., Klein, J. D., Zhang, L., Fang, F., & Mitch, W. E. (2011). Decreased miR-29 suppresses myogenesis in CKD. Journal of the American Society of Nephrology, 22(11), 2068-2076. https://doi.org/10.1681/ASN.2010121302
Ng, C. T., Dheen, S. T., Yip, W. C., Ong, C. N., Bay, B. H., & Yung, L. Y. L. (2011). The induction of epigenetic regulation of PROS1 gene in lung fibroblasts by gold nanoparticles and implications for potential lung injury. Biomaterials, 32(30), 7609-7615. https://doi.org/10.1016/j.biomaterials.2011.06.060
Clément, S., Peyrou, M., Sanchez-Pareja, A., Bourgoin, L., Ramadori, P., Suter, D., ... & Foti, M. (2011). Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. Hepatology, 54(1), 38-49. https://doi.org/10.1002/hep.24362
Sureban, S. M., May, R., Mondalek, F. G., Qu, D., Ponnurangam, S., Pantazis, P., ... & Houchen, C. W. (2011). Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. Journal of Nanobiotechnology, 9(1), 40. https://doi.org/10.1186/1477-3155-9-40
Sureban, S. M., May, R., Ramalingam, S., Subramaniam, D., Natarajan, G., Anant, S., & Houchen, C. W. (2009). Selective blockade of DCAMKL-1 results in tumor growth arrest by a let-7a microRNA-dependent mechanism. Gastroenterology, 137(2), 649-659.e2. https://doi.org/10.1053/j.gastro.2009.04.001
Budde, H., Schmitt, S., Fitzner, D., Opitz, L., Salinas-Riester, G., & Simons, M. (2010). Control of oligodendroglial cell number by the miR-17-92 cluster. Development, 137(13), 2127-2132. https://doi.org/10.1242/dev.048199
Zhang, Y., Diao, Z., Su, L., Sun, H., Li, R., Cui, H., & Hu, Y. (2010). MicroRNA-155 contributes to preeclampsia by down-regulating CYR61. American Journal of Obstetrics and Gynecology, 202(5), 466.e1-466.e7. https://doi.org/10.1016/j.ajog.2010.01.065
Katakowski, M., Buller, B., Wang, X., Rogers, T., & Chopp, M. (2010). Functional microRNA is transferred between glioma cells. Cancer Research, 70(21), 8259-8263. https://doi.org/10.1158/0008-5472.CAN-10-0606
Xin, H., Li, Y., Buller, B., Katakowski, M., Zhang, Y., Wang, X., Shang, X., Zhang, Z. G., & Chopp, M. (2012). Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth. Stem Cells, 30(7), 1556-1564. https://doi.org/10.1002/stem.1129

miRNA Arrays

Kim, M., Jo, H., Kwon, Y., Kim, Y., Jung, H. S., & Jeoung, D. (2020). Homoharringtonine inhibits allergic inflammations by regulating NF-κB-miR-183-5p-BTG1 axis. Frontiers in Pharmacology, 11, 1032. https://doi.org/10.3389/fphar.2020.01032
Yu, D., An, F., He, X., & Cao, X. (2015). Curcumin inhibits the proliferation and invasion of human osteosarcoma cell line MG-63 by regulating miR-138. International Journal of Clinical and Experimental Pathology, 8(11), 14946–14952.
Trindade, A. J., Medvetz, D. A., Neuman, N. A., Myachina, F., Yu, J., & Henske, E. P. (2013). MicroRNA-21 is induced by rapamycin in a model of tuberous sclerosis (TSC) and lymphangioleiomyomatosis (LAM). PLoS One, 8(3), e60014.
Igietseme, J. U., Omosun, Y., Partin, J., Goldstein, J., He, Q., Joseph, K., Ellerson, D., Ansari, U., Eko, F. O., Bandea, C., Zhong, G., & Black, C. M. (2013). Prevention of Chlamydia-induced infertility by inhibition of local caspase activity. Journal of Infectious Diseases, 207(7), 1095-1104. https://doi.org/10.1093/infdis/jit009
Yeh, C. H., Chen, T. P., Wang, Y. C., Lin, Y. M., & Fang, S. W. (2012). MicroRNA27a regulates cardiomyocytic apoptosis during cardioplegia-induced cardiac arrest by targeting interleukin 10-related pathways. Shock, 38(6), 607-614.
Ghosh, A. K., Nagpal, V., Covington, J. W., Michaels, M. A., & Vaughan, D. E. (2012). Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT. Cell Signalling, 24(5), 1031-1036.
Chang, C. C., Zhang, Q. Y., Liu, Z., Clynes, R. A., Suciu-Foca, N., & Vlad, G. (2012). Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8+ T suppressor cells. Journal of Immunology, 188(7), 3042-3052.
Trindade, A. J., Myachina, F., Medvetz, D., Neuman, N., & Henske, E. P. (2011). Microrna expression is dysregulated in lymphangioleiomyomatosis (LAM). American Journal of Respiratory and Critical Care Medicine, 183, A3660.
Jiang, X., & Li, N. (2011). Induction of MiR-17-3p and MiR-160a by TNFα and LPS. Cell Biochemistry and Function, 29(2), 164-170.
Farraj, A. K., Hazari, M. S., Haykal-Coates, N., Lamb, C., Winsett, D. W., Ge, Y., Ledbetter, A. D., Carll, A. P., Bruno, M., Ghio, A., & Costa, D. L. (2011). ST depression, arrhythmia, vagal dominance, and reduced cardiac micro-RNA in particulate-exposed rats. American Journal of Respiratory Cell and Molecular Biology, 44(2), 185-196.
Meganathan, K., & Atreya, C. (2010). Differential profiling of human red blood cells during storage for 52 selected microRNAs. Transfusion, 50(7), 1581-1588.
Le, W., Wang, W., Ghani, M., & Upadhyay, D. (2010). Circulating blood microRNAs in the diagnosis of lung cancer. American Journal of Respiratory and Critical Care Medicine, 181, A3482.
Kannan, M., Mohan, K. V., Kulkarni, S., & Atreya, C. (2009). Membrane array–based differential profiling of platelets during storage for 52 miRNAs associated with apoptosis. Transfusion, 49(7), 1443-1450.

Direct Hybridization Plate Assays

Fragiadaki, M., & Zeidler, M. P. (2018). Ankyrin repeat and Single KH domain 1 (ANKHD1) drives renal cancer cell proliferation via binding to and altering a subset of miRNAs. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.ra117.000975
Nakashima, S., Jinnin, M., Kanemaru, H., Kajihara, I., Igata, T., Okamoto, S., Tazaki, Y., Masuguchi, S., Fukushima, S., Masuzawa, M., Amoh, Y., Masuzawa, M., & Ihn, H. (2017). The role of miR-210, E2F3, and ephrin A3 in angiosarcoma cell proliferation. European Journal of Dermatology. https://doi.org/10.1684/ejd.2017.3084
Mishra, P. K., Raghuram, G. V., Jain, D., Jain, S. K., Khare, N. K., & Pathak, N. (2014). Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells. International Journal of Toxicology, 33(1), 22-33. https://doi.org/10.1177/1091581814523734

Gene Expression Analysis

Single Cell Gene Expression Analysis

Pan, Z., Du, S., Wang, K., Guo, X., Mao, Q., Feng, X., Huang, L., Wu, S., Hou, B., Chang, Y.-J., Liu, T., Chen, T., Li, H., Bachmann, T., Bekker, A., Hu, H., & Tao, Y.-X. (2021). Downregulation of a dorsal root ganglion-specifically enriched long noncoding RNA is required for neuropathic pain by negatively regulating RALY-triggered Ehmt2 expression. Advanced Science, 8(5), 2004515. https://doi.org/10.1002/advs.202004515
Li, Y., Guo, X., Sun, L., Xiao, J., Su, S., Du, S., Li, Z., Wu, S., Liu, W., Mo, K., Xia, S., Chang, Y.-J., Denis, D., & Tao, Y.-X. (2020). N6-methyladenosine demethylase FTO contributes to neuropathic pain by stabilizing G9a expression in primary sensory neurons. Advanced Science. https://doi.org/10.1002/advs.201902402
Meyer, A., Herkt, S., Kunze-Schumacher, H., & others. (2020). The transcription factor TAL1 and miR-17-92 create a regulatory loop in hematopoiesis. Scientific Reports, 10, 21438. https://doi.org/10.1038/s41598-020-78629-z
Luo, H., & others. (2019). Chronological in vivo imaging reveals endothelial inflammation prior to neutrophil accumulation and lipid deposition in HCD-fed zebrafish. Atherosclerosis. https://doi.org/10.1016/j.atherosclerosis.2019.09.017
Shrestha, B., Paul, D., & Pachter, J. S. (2014). Alterations in tight junction protein and IgG permeability accompany leukocyte extravasation across the choroid plexus during neuroinflammation. Journal of Neuropathology and Experimental Neurology.
Zhao, X., Tang, Z., Zhang, H., Atianjoh, F. E., Zhao, J. Y., Liang, L., Wang, W., Guan, X., Kao, S. C., Tiwari, V., Gao, Y. J., Hoffman, P. N., Cui, H., Li, M., Dong, X., & Tao, Y.-X. (2013). A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. Nature Neuroscience, 16(8), 1024-1031.
Manni, S., Brancalion, A., Mandato, E., Tubi, L. Q., Colpo, A., Pizzi, M., Cappellesso, R., Zaffino, F., Di Maggio, S. A., Cabrelle, A., Marino, F., Zambello, R., Trentin, L., Adami, F., Gurrieri, C., Semenzato, G., & Piazza, F. (2013). Protein kinase CK2 inhibition down modulates the NF-κB and STAT3 survival pathways, enhances the cellular proteotoxic stress and synergistically boosts the cytotoxic effect of bortezomib on multiple myeloma and mantle cell lymphoma cells. PLoS One, 8(9), e75280. https://doi.org/10.1371/journal.pone.0075280
Steagall, W. K., Pacheco-Rodriguez, G., Glasgow, C. G., Ikeda, Y., Lin, J. P., Zheng, G., & Moss, J. (2013). Osteoprotegerin contributes to the metastatic potential of cells with a dysfunctional TSC2 tumor-suppressor gene. American Journal of Pathology, 183(3), 938-950.
Ho, Y. K., Xu, W. T., & Too, H. P. (2013). Direct quantification of mRNA and miRNA from cell lysates using reverse transcription real-time PCR: A multidimensional analysis of the performance of reagents and workflows. PLoS One, 8(9), e72463. https://doi.org/10.1371/journal.pone.0072463
Abou-Saleh, H., Pathan, A. R., Daalis, A., Hubrack, S., Abou-Jassoum, H., Al-Naeimi, H., Rusch, N. J., & Machaca, K. (2013). Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility. Journal of Biological Chemistry, 288(46), 32941-32951. https://doi.org/10.1074/jbc.M113.41958
Demarest, T. G., Murugesan, N., Shrestha, B., & Pachter, J. S. (2012). Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan® Low Density Array. Journal of Neuroscience Methods, 206(2), 200-204. https://doi.org/10.1016/j.jneumeth.2012.03.008
Clowney, E. J., Legros, M. A., Mosley, C. P., Clowney, F. G., Markenskoff-Papadimitriou, E. C., Myllys, M., Barnea, G., Larabell, C. A., & Lomvardas, S. (2012). Nuclear aggregation of olfactory receptor genes governs their monogenic expression. Cell, 151(4), 724-737. https://doi.org/10.1016/j.cell.2012.09.043
Murugesan, N., Paul, D., Lemire, Y., Shrestha, B., Ge, S., & Pachter, J. S. (2012). Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus. Fluids and Barriers of the CNS, 9(1), 15. https://doi.org/10.1186/2045-8118-9-15

cDNA Plate Arrays

Wu, Y., Tran, T., Dwabe, S., Sarkissyan, M., Kim, J., Nava, M., Clayton, S., Pietras, R., Farias-Eisner, R., & Vadgama, J. V. (2017). A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells. Breast Cancer Research and Treatment. https://doi.org/10.1007/s10549-017-4211-y
Azevedo, M. M., Tsigkou, O., Nair, R., Jell, G., Jones, J., & others. (2014). HIF-stabilizing bioactive glasses for directing MSC behaviour. Tissue Engineering.
Bodine, B. G., Bennion, B. G., Leatham, E., Jimenez, F. R., Wright, A. J., Jergensen, Z. R., Erickson, C. J., Jones, C. M., Johnson, J. P., Knapp, S. M., & Reynolds, P. R. (2014). Conditionally induced RAGE expression by proximal airway epithelial cells in transgenic mice causes lung inflammation. Respiratory Research.
Qu, D., Weygant, N., May, R., & Chandrakesan, P. (2015). Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis. PLOS ONE. https://doi.org/10.1371/journal.pone.0134212
Costanza, G., Doldo, E., Ferlosio, A., Tarquini, C., Passeri, D., Cascella, R., Bavetta, M., Di Stefani, A., Bonifati, C., Agostinelli, S., Centofanti, F., Giardina, E., Campione, E., Bianchi, L., Donati, P., Morrone, A., & Orlandi, A. (2018). Expression and potential role of cellular retinol binding protein I in psoriasis. Oncotarget, 9(95).
Vadgama, J. V., Wu, Y., Ginther, C., Kim, J., Mosher, N., Chung, S., & Slamon, D. (2012). Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells. Molecular Cancer Research. https://doi.org/10.1158/1541-7786.MCR-12-0260
Isaacs, J. T., Antony, L., Dalrymple, S., Brennen, W. N., Gerber, S., Hammers, H., Wissing, M. D., Kachhap, S. K., Luo, J., Xing, L., Bjork, P., Olsson, A., Björk, A., & Leanderson, T. (2012). Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Research. https://doi.org/10.1158/0008-5472.CAN-12-0480
Qin, X. Y., Wei, F., Yoshinaga, J., Yonemoto, J., Tanokura, M., & Sone, H. (2011). siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells. FEBS Letters, 585(20), 3310-3315. https://doi.org/10.1016/j.febslet.2011.08.040
Sun, D., Jiang, H., Wu, H., Yang, Y., Kaley, G., & Huang, A. (2011). A novel vascular EET synthase: role of CYP2C7. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 301(6), R1723-R1730. https://doi.org/10.1152/ajpregu.00405.2011
Patel, J., Pancholi, N., Gudehithlu, K. P., Sethupathi, P., Hart, P. D., Dunea, G., Arruda, J. A., & Singh, A. K. (2012). Stem cells from foreign body granulation tissue accelerate recovery from acute kidney injury. Nephrology Dialysis Transplantation, 27(5), 1780-1786. https://doi.org/10.1093/ndt/gfr258
Stogsdill, J. A., Stogsdill, M. P., Porter, J. L., Hancock, J. M., Robinson, A. B., & Reynolds, P. R. (2012). Embryonic overexpression of receptors for advanced glycation end-products by alveolar epithelium induces an imbalance between proliferation and apoptosis. American Journal of Respiratory Cell and Molecular Biology, 47(1), 60-66. https://doi.org/10.1165/rcmb.2011-0313OC
Δ-9,11 modifications of glucocorticoids dissociate NF-κB inhibitory efficacy from GRE-associated side effects. Baudy, A. R., Reeves, E., Damsker, J., Heier, C., Garvin, L., Dillingham, B. C., McCall, J., Rayavarapu, S., Wang, Z., Vander Meulen, J., Sali, A., Jahnke, V., Duguez, S., Dubois, D., Rose, M., Nagaraju, K., & Hoffman, E. (2012). Journal of Pharmacology and Experimental Therapeutics. https://doi.org/10.1124/jpet.112.198046
Yakovlev, V. A., Bayden, A. S., Graves, P. R., Kellogg, G. E., & Mikkelsen, R. B. (2010). Nitration of the tumor suppressor protein p53 at tyrosine 327 promotes p53 oligomerization and activation. Biochemistry, 49(25), 5331-5339. https://doi.org/10.1021/bi100564w
Ma, S., Yang, Y., Wang, C., Hui, N., Gu, L., Zhong, H., Cai, Z., Wang, Q., Zhang, Q., Li, N., & Cao, X. (2009). Endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest and apoptosis through down-regulation of the phosphatidylinositide 3-kinase/Akt/HDM2 pathway. Journal of Biological Chemistry, 284(37), 24773-24782. https://doi.org/10.1074/jbc.M109.029185

Biomarkers and Key Proteins

Autoimmune ELISA Kits

Mouse Anti-SSB (La) ELISA Kit (EA-5204)

Ogata, K., Moriyama, M., Kawado, T., Yoshioka, H., Yano, A., Matsumura-Kawashima, M., Nakamura, S., & Kawano, S. (2024). Extracellular vesicles of iPS cells highly capable of producing HGF and TGF-β1 can attenuate Sjögren's syndrome via innate immunity regulation. Cell Signaling, 113, 110980. https://doi.org/10.1016/j.cellsig.2023.110980

Human Eight-ANA ELISA Screen Assay (EA-5101)

Nasser, M., Wadie, M., Farid, A., et al. (2023). Nailfold capillaroscopy in Egyptian systemic lupus erythematosus (SLE) patients: Correlation with demographic features and serum levels of IL-17A and IFNs I. Egyptian Rheumatology & Rehabilitation, 50, 47. https://doi.org/10.1186/s43166-023-00215-8

Cited in Research, Specific Product Unspecified

Frasca, D., et al. (2019). Metabolic requirements of human pro-inflammatory B cells in aging and obesity. PLoS ONE, 14(7), e0219545. https://doi.org/10.1371/journal.pone.0219545
Azzam, K. M., et al. (2017). Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces. JCI Insight, 2(16), e91914. https://doi.org/10.1172/jci.insight.91914
Ding, C., Chen, X., Dascani, P., Hu, X., Bolli, R., & Zhang, H. (2016). STAT3 signaling in B cells is critical for germinal center maintenance and contributes to the pathogenesis of murine models of lupus. The Journal of Immunology. Advance online publication. https://doi.org/10.4049/jimmunol.1502043
Shen, L., Zhang, H., Caimol, M., & Benike, C. J. (2014). Invariant natural killer T cells in lupus patients promote IgG and IgG autoantibody production. European Journal of Immunology. Advance online publication.

Others

Signosis Luciferase Substrate

Huang, L. N., Zou, Y., Wu, S. G., Zhang, H. H., Mao, Q. X., Li, J. B., & Tao, Y. X. (2019). Fn14 participates in neuropathic pain through the NF-κB pathway in primary sensory neurons. Molecular Neurobiology, 56(10), 7085-7096. https://doi.org/10.1007/s12035-019-1545-y
Wu, Q., Zhang, L., Wang, H., Zhang, Y., Chen, X., Li, G., & Wei, H. (2018). TET1 overexpression mitigates neuropathic pain through rescuing the expression of μ-opioid receptor and Kv1.2 in the primary sensory neurons. Neurotherapeutics. https://doi.org/10.1007/s13311-018-00689-x
Zimmerman, M. C., Clemens, D. L., Duryee, M. J., Sarmiento, C., Chiou, A., Hunter, C. D., Tian, J., Klassen, L. W., O’Dell, J. R., & Thiele, G. M. (2017). Direct antioxidant properties of methotrexate: Inhibition of malondialdehyde-acetaldehyde-protein adduct formation and superoxide scavenging. Redox Biology. https://doi.org/10.1016/j.redox.2017.07.018

Quick Lead Time | Global Overnight Delivery Available

Purchase Order: info@signosisinc.com

Stable Cell Line

Luciferase Reporter Stable Cell Lines

NFAT Jurkat Stable Cell Lines

Transcription Factor Assays

TF Activation Profiling Plate Arrays

Combo TF Activation (FA-1106)

TF Activation Profiling Plate I (FA-1001)

TF Activation Profiling Plate II (FA-1002)

TF Activation Profiling Plate III (FA-1101)

Stem Cell (FA-1003)

Cancer Stem Cell (FA-1004)

Oxidative Stress (FA-1005)

ER Stress (FA-1006)

Wnt/Beta-Catenin (FA-1007)

Cholesterol Metabolism (FA-1008)

Mitochondria UPR (FA-1010)

Cited in Research, Specific Product Unspecified

Promoter Binding TF Assays

Promoter Binding 1 (FA-2001)

Promoter Binding 2 (FA-2002)

Cited in Research, Specific Product Unspecified

TF Interaction Plate Arrays

He, T. (2021). Identification and clinical significance of two divergent regulators in thoracic malignancy: miR-18a and RUNX1T1 [Doctoral dissertation, Case Western Reserve University].

EMSA

STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimer's disease animal model. Wan HL, Hong XY, Zhao ZH, et al. (2021). *Theranostics, 11*(11), 5511-5524. https://doi.org/10.7150/thno.56541

Dutta, P., Paico, K., Gomez, G., Wu, Y., & Vadgama, J. (2020). Transcriptional regulation of CCL2 by PARP1 is a driver for invasiveness in breast cancer. *Cancers, 12*(5), 1317. https://doi.org/10.3390/cancers12051317

McCormack, R., Hunte, R., Podack, E. R., Plano, G. V., & Shembade, N. (2020). An essential role for perforin-2 in type I IFN signaling. *The Journal of Immunology*. https://doi.org/10.4049/jimmunol.1901013

Henry, D., Arora, R., Mannel, J., Tripathi, S., Bhattacharya, D., & Velagapudi, R. (2019). Involvement of pRb-E2F pathway in green tea extract-induced growth inhibition of human myeloid leukemia cells. *Leukemia Research*. https://doi.org/10.1016/j.leukres.2018.12.014

Li, X., Cai, X., Zhang, X., Li, Q., Feng, X., Wei, J., ... & Zhen, J. (2018). Tau accumulation activates STAT1 triggering memory deficits via suppressing NMDA receptor expression. *doi:10.1101/437814*.

Zhang, L., Zhao, J., Gurkar, A., Niedernhofer, L. J., & Robbins, P. D. (2018). Methods to quantify the NF-κB pathway during senescence. *Methods in Molecular Biology, Cellular Senescence*, 231–250. https://doi.org/10.1007/978-1-4939-8931-7_18

Jiang, X., Engel, B. J., Liu, H., Inouye, C., Nunez, S., Palomares, M., & Tong, Z. (2017). Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. *Nature Communications, 8*(1). https://doi.org/10.1038/s41467-017-02290-w

Wang, S., Sun, Z., Zhao, W., Wang, Z., Wu, M., Pan, Y., Yan, H., & Zhu, J. (2016). CD97/ADGRE5 inhibits LPS induced NF

TF Filter Plate Assays

TF ELISA Kits

NRF2 ELISA

STAT3 ELISA

TF Luciferase Reporter Vectors

Cytokines ELISA

Cytokine ELISA Plate Arrays

Mouse Cytokine ELISA Plate Array I (Chemiluminescence) (EA-4003)

Mouse Cytokine ELISA Plate Array I (Colorimetric) (EA-4005)

Human Cytokine ELISA Plate Array I (Chemiluminescence) (EA-4001)

Human Cytokine ELISA Plate Array I (Colorimetric) (EA-4002)

Human Cytokine ELISA Plate Array IV (Colorimetric) (EA-4015)

Human Angiogenesis ELISA Plate Array (Colorimetric) (EA-4012)

Rat Cytokine ELISA Plate Array (Colorimetric) (EA-4006)

Cited in Research, Specific Product Unspecified

Human Cytokine ELISA Strips

Human Inflammation ELISA Strip (Chemiluminescence) (EA-1621)

Human Angiogenesis ELISA Strip II (Chemiluminescence) (EA-1631)

Human Inflammation ELISA Strip (Colorimetric) (EA-1031)

Cited in Research, Specific Product Unspecified

Mouse Cytokine ELISA Strips

Mouse Obesity ELISA Strip (Chemiluminescence) (EA-1721)

Mouse Cytokine ELISA Strip (Chemiluminescence) (EA-1731)

Mouse Angiogenesis ELISA Strip (Chemiluminescence) (EA-1701)

Mouse Oxidative Stress ELISA Strip (Chemiluminescence) (EA-1741)

Mouse Cytokine ELISA Strip (Colorimetric) (EA-1091)

Mouse Obesity ELISA Strip I (Colorimetric) (EA-1071)

Mouse Angiogenesis ELISA Strip (Colorimetric) (EA-1021)

Mouse Oxidative Stress ELISA Strip (Colorimetric) (EA-1401)

Cited in Research, Specific Product Unspecified

Rat Cytokine ELISA Strips

Rat Inflammation ELISA Strip (Chemiluminescence) (EA-1801)

Rat Angiogenesis ELISA Strip (Chemiluminescence) (EA-1811)

Rat Inflammation ELISA Strip (Colorimetric) (EA-1201)

Rat Angiogenesis ELISA Strip (Colorimetric) (EA-1211)

​

Cited in Research, Specific Product Unspecified

Human Cytokine ELISA Kits

Human TNFα ELISA (EA-0203)

Human Resistin ELISA (EA-0205)

Human IL-6 ELISA (EA-0206)

Human PDGF-BB ELISA (EA-0404)

Human IL-1α ELISA (EA-0503)

​Cited in Research, Specific Product Unspecified

​

Mouse Cytokine ELISA Kits

STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimer's disease animal model. Wan HL, Hong XY, Zhao ZH, et al. (2021). Theranostics, 11(11), 5511-5524. https://doi.org/10.7150/thno.56541

Dutta, P., Paico, K., Gomez, G., Wu, Y., & Vadgama, J. (2020). Transcriptional regulation of CCL2 by PARP1 is a driver for invasiveness in breast cancer. Cancers, 12(5), 1317. https://doi.org/10.3390/cancers12051317

McCormack, R., Hunte, R., Podack, E. R., Plano, G. V., & Shembade, N. (2020). An essential role for perforin-2 in type I IFN signaling. The Journal of Immunology. https://doi.org/10.4049/jimmunol.1901013

Henry, D., Arora, R., Mannel, J., Tripathi, S., Bhattacharya, D., & Velagapudi, R. (2019). Involvement of pRb-E2F pathway in green tea extract-induced growth inhibition of human myeloid leukemia cells. Leukemia Research. https://doi.org/10.1016/j.leukres.2018.12.014

Li, X., Cai, X., Zhang, X., Li, Q., Feng, X., Wei, J., ... & Zhen, J. (2018). Tau accumulation activates STAT1 triggering memory deficits via suppressing NMDA receptor expression. doi:10.1101/437814.

Zhang, L., Zhao, J., Gurkar, A., Niedernhofer, L. J., & Robbins, P. D. (2018). Methods to quantify the NF-κB pathway during senescence. Methods in Molecular Biology, Cellular Senescence, 231–250. https://doi.org/10.1007/978-1-4939-8931-7_18

Jiang, X., Engel, B. J., Liu, H., Inouye, C., Nunez, S., Palomares, M., & Tong, Z. (2017). Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Nature Communications, 8(1). https://doi.org/10.1038/s41467-017-02290-w

Cited in Research, Specific Product Unspecified

Cited in Research, Specific Product Unspecified