The Mouse Eight‑ANA ELISA Screen Kit enables specific, differentiated detection of eight individual anti‑nuclear autoantibodies in mouse serum or plasma. Unlike conventional ANA ELISAs that measure total ANA in a single well, this kit uses eight antigens coated separately across a single strip, allowing direct comparison of individual autoantibody responses in one run. This provides much higher interpretive power for autoimmune research in murine models.
Each strip includes wells coated with dsDNA, SmD1, U1‑RNA (68K), SS‑A/Ro, SS‑B/La, Scl‑70, Jo‑1, and CENP‑B, enabling detailed profiling associated with conditions such as SLE, Sjögren’s syndrome, scleroderma, and mixed connective tissue disease.
Designed specifically for mouse studies, the kit supports efficient use of limited serum volumes, offering a streamlined workflow for longitudinal studies, therapeutic response assessments, and autoimmune model characterization. The antigen‑separated design delivers superior specificity and clarity compared to traditional total‑ANA tests, making it a powerful tool for researchers who need precise autoantibody differentiation in murine systems.
