Fibroblast growth factor (FGF)-2, also known as basic FGF (FGFb), is a powerful stimulator of angiogenesis in vivo, in addition to being a pleiotropic regulator of the proliferation, migration, differentiation, and survival of many cell types in vitro, including endothelial cells, smooth muscle cells, and pericytes.  It is capable of inducing an angiogenic response both in vivo and in vitro. Both basic and acidic FGFs, a heparin-binding family of structurally related cytokines, are widely expressed during embryonic development and normal wound healing, as well as in such angioproliferative diseases as cancer and diabetes.
 
Detection Range:
    16 - 1000 pg/mL
Sensitivity:
    12 pg/mL