The Signosis Anti-CD19 CAR/NFAT Luciferase Reporter Jurkat Stable Cell Line is a genetically engineered T-cell reporter model designed for sensitive and quantitative evaluation of CD19-directed chimeric antigen receptor (CAR) signaling. This stable Jurkat cell line combines anti-CD19 CAR expression with an NFAT-responsive luciferase reporter system, enabling researchers to monitor antigen-dependent CAR activation through a convenient bioluminescent readout.
 
Developed using lentiviral transduction and single-cell clone selection, this reporter cell line has undergone functional characterization to identify a clone with strong reporter responsiveness and CAR expression.