The GU-Rich Element, GRE RNA EMSA Kit is designed to study RNA-protein interactions involving GU-rich regulatory RNA sequences associated with mRNA decay and transcript stability. GU-rich elements are recognized by RNA-binding proteins such as CELF1/CUGBP1, which participate in post-transcriptional regulation of gene expression.
This kit is useful for researchers studying mRNA turnover, RNA stability, muscle biology, neurological disease models, cancer biology, and RNA decay pathways. It provides a practical RNA EMSA assay for detecting GU-rich element binding activity in biological samples.