IL-1RA (Interleukin-1 Receptor Antagonist) is a member of the interleukin-1 family of cytokines.  It non-productively binds the IL-1 receptor thereby modulating the pro-inflammatory effects of IL-1α and IL-1β.  Mutations in IL-1RA have been linked to osteoporotic fractures, gastric cancer, schizophrenia, and the rare disease Deficiency of the Interleukin-1 Receptor Antagonist (DIRA).  Recombinant IL-1RA is currently used to treat autoimmune disorders and lymphomas.
 
Detection Range:
    16 - 1000 pg/mL
Sensitivity:
    8 pg/mL