The peroxisome-proliferator activated receptor gamma (PPARgamma) is a member of the nuclear receptor superfamily of transcription factors. PPARgamma is important to a variety of biological processes, such as adipocyte differentiation, glucose homeostasis, lipid trafficking as well as vascular function and hypertension. PPARgamma exerts its effects by regulating target gene transcription in a ligand-dependent manner. Upon activation, the PPARgamma-RXR heterodimer binds to specific DNA sequences on the target gene promoter and leads to transcriptional regulation. Signosis has developed a plate-based array for profiling 20+ PPARgamma-regulated genes. By using this assay, researchers are able to compare gene expression in up to three samples on a single microtiter plate.
Human P450 cDNA Plate Array
SKU: AP-0202
$681.00Price
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