T-Cells are a subset of lymphocytes that play a key role in the immune response. T-Cell Receptor (TCR) is a complex of integral membrane proteins that participates in the activation of T-Cells in response to antigen. This activation involves subunits of the receptor complex as well as other membrane-associated molecules that couple the extracellular liganding event to downstream signaling pathways such as the increase of inositol phosphates, the elevation of intracellular calcium levels and protein phosphorylation. TCR activation promotes a number of signaling cascades that ultimately determine cell fate through regulating cytokine production, cell survival, proliferation, and differentiation. Signosis has developed a plate-based array for profiling 20+ Human T Cell-regulated genes. By using this assay, researchers are able to compare gene expression in up to three samples on a single microtiter plate.
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SKU: AP-0191
$681.00Price
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