Forkhead-related activator (FREAC) is a transcription factor that plays a critical role in regulating cell growth, differentiation, metabolism, and immune responses. The FREAC luciferase reporter vector is designed to study the transcriptional activity of FREAC. The vector contains a FREAC DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report FREAC activity while maintaining a low basal level of transcription.
 
The inclusion of a hygromycin resistance gene in the vector allows it to be used for stable cell line selection. Additionally, a GFP-tagged version of the vector is available for monitoring transfection efficiency. Maps of the vector, including hygromycin and GFP configurations, can be found in the product's image gallery.