Prospero homeobox 1 (Prox1) is a transcription factor that plays a crucial role in various biological processes, including embryonic development, lymphangiogenesis, neurogenesis, and cardiogenesis. The Prox1 luciferase reporter vector is designed to study the transcriptional activity of Prox1. The vector contains a Prox1 DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report Prox1 activity while maintaining a low basal level of transcription.
The inclusion of a hygromycin resistance gene in the vector allows it to be used for stable cell line selection. Additionally, a GFP-tagged version of the vector is available for monitoring transfection efficiency. Maps of the vector, including hygromycin and GFP configurations, can be found in the product's image gallery.
pProx1-Luc-hyg
Literature
Data
Citations