The Human Eight‑ANA ELISA Screen Assay enables specific, differentiated detection of eight individual anti‑nuclear autoantibodies in human serum or plasma. Unlike traditional ANA ELISAs that measure total ANA in a single well, this kit uses eight antigens coated separately across a single strip, allowing direct comparison of individual autoantibody responses in one run. This design provides significantly enhanced clarity for autoimmune research and for studying antibody profiles associated with human connective‑tissue disorders.
Each strip includes wells coated with dsDNA, SmD1, U1‑RNP (68K), SS‑A/Ro, SS‑B/La, Scl‑70, Jo‑1, and CENP‑B, enabling detailed profiling associated with conditions such as SLE, Sjögren’s syndrome, scleroderma, mixed connective tissue disease, and related autoimmune conditions.
The assay format supports efficient and precise profiling of human autoimmune responses, particularly useful in research involving patient sera, biomarker studies, and human disease stratification. The antigen‑separated design delivers superior specificity and clarity compared to traditional total‑ANA tests, making it a powerful tool for researchers who need precise autoantibody differentiation critical for human autoimmune research.
