Reporter Systems
Luciferase Tools for Gene Regulation and Pathway Studies
Signosis Reporter Systems provide functional, cell-based tools for measuring gene regulation, pathway activation, promoter activity, transcription factor signaling, and miRNA-mediated regulation. Our reporter products convert biological activity into sensitive luminescent readouts, making them ideal for drug screening, target validation, pathway analysis, and gene expression studies.
Different reporter formats are available depending on whether the goal is to measure pathway activation, promoter activity, miRNA regulation, stable expression, or luciferase assay detection.
Product Categories
TF Luciferase Reporter Vectors
For measuring pathway activity, transcription factor response, and gene regulation.
Includes: Firefly luciferase reporter vectors, Renilla luciferase reporter vectors, and dual luciferase reporter vectors containing both Firefly and Renilla reporters.
Select vectors are also available with hygromycin or neomycin selection, with optional GFP marker support.
Lentiviral Expression Systems
For standardized lentiviral production, gene delivery, and stable expression in mammalian cells.
Includes: A complete lentiviral production workflow with optimized producer cells, transfection reagent, packaging mix, concentration solution, infection reagent, compatible transfer vectors, and custom lentiviral services.
Luciferase Substrates
Detect Firefly, Renilla, Gaussia, and dual luciferase activity with ready-to-use, one-solution substrates.
Includes: Stable luciferase detection reagents for reporter vectors, stable cell lines, transcription factor assays, gene expression studies, pathway analysis, and high-throughput screening.
Promoter Reporter Vectors
For measuring native gene promoter activity and transcriptional regulation in response to pathway activation, drug treatment, or disease-relevant stimuli.
Includes: Gene-specific promoter luciferase reporter vectors for studying native promoter activity across inflammation, stress response, metabolism, and major signaling pathways.