miRNAs have been shown to regulate many developmental and physiological processes, and the deregulation of miRNAs has been linked to a number of diseases, including cancer. miRNAs play important roles in fine-tuning gene expression regulators, referred to as “dimmer switches”, because of their ability to repress gene expression without completely silencing it. The precise measurement of miRNA expression, particularly in a cell-based assay, can help scientists better understand the impact of miRNA on cancer etiology, differential stages, and therapy development.  

Signosis offers over 100 different miRNA luciferase reporter vectors to study miRNA expression in cells. In addition, custom services are available for any miRNAs that are not listed on our catalog.