Signosis' EL-011 is a stable Ba/F3 cell line expressing EGFR with the exon 19 deletion del747-753InsS. This in-frame deletion occurs near the ATP-binding site and is frequently observed in NSCLC patients. The cell line was generated using an MSCV-IRES-EGFP retroviral construct, with GFP fluorescence enabling selection by FACS. Clones were validated for EGFR authenticity and protein expression by PCR sequencing and Western blot.
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SKU: EL-011
$3,870.00Price
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