Signosis' EL-040 is a stable Ba/F3 cell line expressing EGFR with the L718Q, L858R, and T790M point mutations. The cell line was generated by electroporation with a vector containing the mutant EGFR gene, along with GFP and hygromycin resistance. Clones were selected based on hygromycin resistance, GFP expression, and confirmed mutant EGFR protein expression.
EL-040 EGFR (L718Q, T790M, L858R) BaF3 Stable Cell Line
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