CCAAT displacement protein (CDP) is a transcription factor that plays a crucial role in cellular stress responses, particularly in the unfolded protein response and endoplasmic reticulum stress. The CDP luciferase reporter vector is designed to study the transcriptional activity of CDP. The vector contains a CDP DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report CDP activity while maintaining a low basal level of transcription. It also contains the Renilla Luciferase under the CMV promoter for data normalization.