Paired box gene 3 (Pax3) is a transcription factor that plays a critical role in embryonic development, particularly in the formation of somites, neural crest cells, and muscle cells. The Pax3 luciferase reporter vector is designed to study the transcriptional activity of Pax3. The vector contains a Pax3 DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report Pax3 activity while maintaining a low basal level of transcription.
 
The inclusion of a neomycin resistance gene in the vector allows it to be used for stable cell line selection. In addition, the vector also has a GFP-tag which can be used to monitor transfection efficiency. A map of the vector can be found in the product's image gallery.