Paired box gene 6 (Pax6) is a transcription factor that plays a key role in the development of various tissues, particularly in the eye, central nervous system, and pancreas. The Pax6 luciferase reporter vector is designed to study the transcriptional activity of Pax6. The vector contains a Pax6 DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report Pax6 activity while maintaining a low basal level of transcription.
 
The inclusion of a neomycin resistance gene in the vector allows it to be used for stable cell line selection. In addition, the vector also has a GFP-tag which can be used to monitor transfection efficiency. A map of the vector can be found in the product's image gallery.