SOCS3, or Supressor of Cytokine Signaling 3, is a protein involved in negatively regulating immune responses and cell signaling pathways. The SOCS3 Promoter luciferase reporter vector is designed for studying the regulation of SOCS3. The vector contains the SOCS3 promoter region upstream of a firefly luciferase reporter gene, which can specifically report activity for SOCS3 activity.