Mouse Autoimmune ELISA Kits
Signosis offers a comprehensive suite of Mouse Autoimmune ELISA Kits designed for the sensitive detection and absolute quantification of autoantibodies in mouse models. Covering a wide range of research applications—including Sjögren's syndrome, scleroderma, rheumatoid arthritis, antiphospholipid syndrome, primary biliary cholangitis, Type 1 diabetes, and multiple sclerosis—our portfolio spans systemic ANA markers (dsDNA, Sm, Ro-52), organ-specific panels (AMA-M2, GADA, IA-2A), and myelin protein targets (MBP, MOG). Each kit includes a validated antibody standard and features a flexible 12×8-well strip plate format, providing the reliability and ease of use necessary to monitor immune dysfunction and disease progression with confidence.
Principle
Signosis’ Autoimmune ELISA Kits detect autoimmune antibodies in mouse serum using a standard ELISA format. A specific antigen is pre-coated onto microtiter wells to capture the target antibodies. During the assay, the sample is added, and autoimmune antibodies, if present, bind to the immobilized antigen. An HRP-conjugated anti-mouse IgG antibody is then added, forming a complex. After washing away unbound proteins, TMB substrate is added, which reacts with HRP to form a blue color. Then, Stop solution is added to terminate the reaction and change the blue color to yellow. The intensity of the yellow color, measured at an absorbance of 450 nm, is directly proportional to the concentration of autoimmune antibodies in the sample.
All Mouse Autoimmune ELISA Kits
Antigen | Product | SKU | Price (USD$) |
|---|---|---|---|
β2-GP1 IgM | EA-5222 | 570 | |
CL IgM | EA-5225 | 570 | |
CL IgA | EA-5226 | 570 | |
β2-GP1 IgA | EA-5223 | 570 | |
GAD65 | EA-5211 | 570 | |
RF IgA | EA-5219 | 570 | |
IA-2A | EA-5214 | 570 | |
gp210 | EA-5228 | 570 | |
RF IgM | EA-5217 | 570 | |
MBP | EA-5230 | 570 | |
TPO | EA-5212 | 570 | |
SSA (Ro-60) | EA-5202 | 570 | |
IF | EA-5213 | 570 | |
8 Antigen Panel | EA-5102 | 713 | |
SSB (La) | EA-5204 | 570 | |
CL IgG | EA-5224 | 570 | |
β2-GP1 IgG | EA-5221 | 570 | |
RF IgG | EA-5220 | 570 | |
CCP | EA-5218 | 570 | |
IAA | EA-5216 | 570 | |
SmD1 | EA-5209 | 570 | |
Histone | EA-5208 | 570 | |
AMA-M2 | EA-5227 | 570 | |
CENP-B | EA-5206 | 570 | |
ICA | EA-5215 | 570 | |
sp100 | EA-5229 | 570 | |
MOG | EA-5231 | 570 | |
SSA (Ro-52) | EA-5203 | 570 | |
Jo-1 | EA-5207 | 570 | |
dsDNA | EA-5201 | 570 | |
Scl-70 | EA-5205 | 570 |
Benefits
Complete Disease Coverage
Whether you are studying Lupus (ANA), MS (MBP/MOG), or Diabetes (GADA), our expanded portfolio offers a unified platform for your entire lab.
High Sensitivity
Optimized for mouse-specific samples (serum, plasma, lysates).
Comprehensive Selection of Markers
Analyze a wide range of autoimmune antibodies, including antibodies which target dsDNA, SSA/Ro, SSB/La, histone, and more.
User-Friendly Design
Pre-coated plates with 12x8 detachable strips provides flexibility in experiments.
Absolute Quantitation
Every kit includes an antibody standard.
Compatible with Multiple Sample Types
Suitable for serum, plasma, and other sample types from mouse models.