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Luciferase Substrate


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High signal and responsive

Produces strong and stable light signal.

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Simple, easy to use

One-step solutions

Ready to use without any prior preparation or mixing needed

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Works with all Signosis luciferase products and third-party firefly luciferase systems

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Cost Effective


Less $ spent per reaction compared to our competitors

EGFR Vectors


Mutations in the epidermal growth factor receptor (EGFR) gene are commonly observed in many type of cancers including lung, colorectal, head and neck and breast cancer. These mutations play an important role in particular in non-small-cell lung cancer as they can be not only therapeutic target but also a predictive tool for response to EGFR tyrosine kinase inhibitors such as gefitinib and erlotinib. Cell lines have played crucial roles in the identification and characterization of these driver mutations.

Signosis has developed expression vectors for the most common EGFR mutations harboring FLAG marker with high expression suitable for your cancer research. We also accept any other customized EGFR mutation for your research need, contact us for more information. 



Cell Vialbility Assay (CVC)


Cell Viability/Cytotoxicity (CVC) Reagent is a colorimetric WST-8 based assay that provides a simple and accurate method to measure cell proliferation. This is a tetrazolium reduction assays based on the cleavage of the tetrazolium salt WST-8 to water-soluble, orange formazan dye by cellular mitochondrial dehydrogenases (Fig.1). Intensity of dye is a direct proportion of increased activity of the mitochondrial dehydrogenases and therefore number of viable cells which can be quantified by measuring the absorbance at 450 nm.

Ready to use CVC Reagent allow for rapid, sensitive and reliable method for measuring cell viability/cytotoxicity directly from a 96-well plate without any additional processing.

WST-8 Assay Mechanism

Client Inquiries

407 747 0771

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