Signosis' EL-046 EGFR del19 (746–750) & T790M + cMET cell line is a stable Ba/F3 cell line co-expressing EGFR with exon 19 deletion (AA 746–750), the T790M mutation, and cMET overexpression. The cell line was generated by electroporation with two vectors: one containing mutant EGFR with GFP and hygromycin resistance, and the other containing cMET with G418 resistance. Clones were selected based on dual drug resistance, GFP expression, and confirmed protein expression of both EGFR and cMET.