FOXH1 is a transcription factor in the Forkhead box family of proteins and plays a significant role in the regulation of mesodermal differentiation and embryonic development. The FOXH1 luciferase reporter vector is designed to study the transcriptional activity of FOXH1. The vector contains a FOXH1 DNA consensus binding site and TA minimal promoter upstream of a firefly luciferase reporter gene, which can specifically report FOXH1 activity while maintaining a low basal level of transcription.
 
The inclusion of a hygromycin resistance gene in the vector allows it to be used for stable cell line selection. Additionally, a GFP-tagged version of the vector is available for monitoring transfection efficiency. Maps of the vector, including hygromycin and GFP configurations, can be found in the product's image gallery.