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Associated Reagents for Luciferase Reporter Cell Lines

Signosis offers everything you need for our TF Luciferase Reporter Cell Lines in one place. Our ready-to-use reagents make your experiments easier, faster, and more reliable.

Principle 

Reporter gene assays are a cornerstone of modern cell-based research, allowing direct and quantitative measurement of pathway activity in response to stimuli. While stable reporter cell lines provide the foundation for these assays, achieving consistently reproducible and biologically relevant results depends heavily on the surrounding experimental context, including media composition, inducer quality, detection reagents, and timing.

​​

Signosis' Luciferase Reporter Cell Line reagents are a curated collection of pathway-specific components designed to support optimal assay performance. These include pre-qualified inducers, inhibitors, detection substrates, and media formulations that have been validated with our own reporter cell lines and are fully compatible with standard luciferase-based systems. Specifically formulated to enhance the performance of our TF Luciferase Reporter Cell Lines, these reagents provide the necessary tools to maximize luciferase expression and induction for consistent, high-quality results.

​By providing researchers with ready-to-use, assay-matched reagents, this product line simplifies experimental setup, reduces variability, and ensures consistent signal output — whether you’re screening compounds, validating hits, or probing pathway dynamics. The reagents are modular and can be used individually or in combination, giving you the flexibility to design and optimize your own reporter assays with confidence.

Culture Media

Pre-formulated, ready-to-use culture, assay, and freezing media optimized for luciferase reporter cell lines. Can be used directly out of the box without further preparation.

Media Type
Name
SKU
Price (USD$)
DMEM
Complete Growth Maintenance Media (DMEM, G418) (50 mL)
CC-0003G
$71.00
DMEM
Complete Growth Maintenance Media (DMEM, G418) (500 mL)
CC-0509G
$240.00
DMEM
Complete Growth Maintenance Media (DMEM, hygromycin B) (50 mL)
CC-0003H
$70.00
DMEM
Complete Growth Maintenance Media (DMEM, hygromycin B) (500 mL)
CC-0509H
$230.00
EMEM
Complete Growth Maintenance Media (EMEM, G418) (50 mL)
CC-0004G
$71.00
EMEM
Complete Growth Maintenance Media (EMEM, G418) (500 mL)
CC-0510G
$240.00
EMEM
Complete Growth Maintenance Media (EMEM, hygromycin B) (50 mL)
CC-0004H
$70.00
EMEM
Complete Growth Maintenance Media (EMEM, hygromycin B) (500 mL)
CC-0510H
$230.00
RPMI
Complete Growth Maintenance Media (RPMI, G418) (50 mL)
CC-0005G
$71.00
RPMI
Complete Growth Maintenance Media (RPMI, G418) (500 mL)
CC-0511G
$240.00
RPMI
Complete Growth Maintenance Media (RPMI, hygromycin B) (50 mL)
CC-0005H
$70.00
RPMI
Complete Growth Maintenance Media (RPMI, hygromycin B) (500 mL)
CC-0511H
$230.00
DMEM
Complete Growth Media (DMEM) (50 mL)
CC-0003
$69.00
DMEM
Complete Growth Media (DMEM) (500 mL)
CC-0509
$210.00
EMEM
Complete Growth Media (EMEM) (50 mL)
CC-0004
$69.00
EMEM
Complete Growth Media (EMEM) (500 mL)
CC-0510
$210.00
RPMI
Complete Growth Media (RPMI) (50 mL)
CC-0005
$69.00
RPMI
Complete Growth Media (RPMI) (500 mL)
CC-0511
$210.00
DMEM
Freezing Media (DMEM) (100 mL)
CC-0506
$96.00
DMEM
Freezing Media (DMEM) (50 mL)
CC-0006
$73.00
EMEM
Freezing Media (EMEM) (100 mL)
CC-0507
$96.00
EMEM
Freezing Media (EMEM) (50 mL)
CC-0007
$73.00
RPMI
Freezing Media (RPMI) (100 mL)
CC-0508
$96.00
RPMI
Freezing Media (RPMI) (50 mL)
CC-0008
$73.00
RPMI
Hormone Assay Treatment Media (150 mL)
CC-0502
$75.00
RPMI
Hormone Assay Treatment Media (50 mL)
CC-0002
$59.00
RPMI
Hormone Depletion Conditioning Media (150 mL)
CC-0501
$135.00
RPMI
Hormone Depletion Conditioning Media (50 mL)
CC-0001
$80.00

Inducers 

A curated selection of small molecules and cytokines that have been fully validated for functional activation of specific pathways using our TF Luciferase Reporter Cell Lines, ensuring compatibility and reliable assay performance.

Target Pathway
Name
SKU
Formatted Price
Estrogen Receptor
Beta-Estradiol solution (1000x)
IA-0007
$98.00
SMAD/BMP
BMP10 solution (1000x)
IA-0027
$98.00
SMAD/BMP
BMP2 solution (1000x)
IA-0020
$98.00
SMAD/BMP
BMP7 solution (1000x)
IA-0025
$98.00
SMAD/BMP
BMP9 solution (1000x)
IA-0026
$98.00
HIF
Desferrioxamine (DFO) solution (1000x)
IA-0012
$98.00
GR
Dexamethasone (Dex) solution (1000x)
IA-0011
$98.00
AR
Dihydrotestosterone (DHT) solution (1000x)
IA-0003
$98.00
ELK
Epidermal Growth Factor (EGF) solution (1000x)
IA-0005
$98.00
GLP-1R/CREB
Exedin-4 solution (1000x)
IA-0010
$98.00
CREB
Forskolin solution (1000x)
IA-0004
$98.00
FXR
GW4064 solution (1000x)
IA-0008
$98.00
IFNa
Interferon alpha (IFNa) solution (100x)
IA-0013
$98.00
GAS/Stat1, IRF, STAT1
Interferon gamma (IFNg) solution (100x)
IA-0009
$98.00
STAT3
Interleukin-6 (IL6) solution (100x)
IA-0022
$98.00
ELK-TAD
MEKK solution (1000x)
IA-0006
$98.00
NFAT
Phorbol 12-myristate 13-acetate (PMA) + Ionomycin solution (1000x)
IA-0015
$98.00
AP1
Phorbol 12-myristate 13-acetate (PMA) solution (1000x)
IA-0002
$98.00
p53
Quinacrine solution (1000x)
IA-0018
$98.00
RAR
Retinoic Acid solution (1000x)
IA-0019
$98.00
XRE
TCDD solution (1000x)
IA-0024
$98.00
NRF2/ARE
Tert-Butylhydroquinone (TBHQ) solution (1000x)
IA-0017
$98.00
AARE, ATF4, ATF6, CHOP, ER Stress-ERSE
Thapsigargin (TG) solution (1000x)
IA-0001
$98.00
SMAD/TGFB
Transforming Growth Factor beta (TGFB) solution (100x)
IA-0021
$98.00
NFkB
Tumor Necrosis Factor-alpha (TNFa) solution (100x)
IA-0016
$98.00
TCF/LEF
Wnt+LiCl solution (1000x)
IA-0023
$98.00
MRF
ZnSO4 solution (1000x)
IA-0014
$98.00

Selection Antibiotics

Selection agents to maintain and validate stable reporter cell line expression.

Client Inquiries

407 747 0771

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